3 results about "Hydroxizinum" patented technology

This invention discloses a 2-phenylimidazo[1,2-] α This paper describes pyridine compounds, their preparation methods, and applications, belonging to the field of pharmaceutical technology. These compounds use imidazo[1,2-α]pyridine as the core skeleton and are prepared via a three-step method: first, cyclization of 2-aminopyridine with hydroxyacetophenone yields intermediate LT1-6; then, etherification with a brominated carboxylic acid ester yields LT7-48; finally, hydroxylamine hydrolysis converts them into the target product HDDI1-42, which contains an isohydroxamic acid group. Activity tests show that these compounds possess significant HDAC1 inhibitory activity and anti-tumor cell proliferation activity.

The application provides a kind of hydroxamic acid and its synthesis method and application, the hydroxamic acid has the structure shown in formula M, the distance of two hydroxylamine groups in the structure of the hydroxamic acid is more appropriate, more easily adjust and match the distance between mineral surface metal ions, can show excellent flotation effect in mineral flotation.