Anti adhesion protective preparation

A protective agent and anti-adhesion technology, applied in the direction of organic active ingredients, surgical drugs, medical preparations containing active ingredients, etc., to achieve the effect of reducing blood extravasation, considerable economic benefits, and easy to accept

Inactive Publication Date: 2005-06-08
TIANJIN CITY AGRI BIO TECH RES CENT +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The relatively advanced conventional technology, animal recipients receive 2 times of embryo transfer, which will also be eliminated due to adhesion problems

Method used

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  • Anti adhesion protective preparation

Examples

Experimental program
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Effect test

preparation example Construction

[0026] The preparation method of aforementioned anti-blocking protective agent is:

[0027] First, measure the dihydrate C of oxytetracycline of proportioning amount 45% 22 h 26 N 2 o 11 , 3% of the new anticoagulant C 19 h 16 o 6 N, 2% epinephrine C 9 h 14 o 3 N, 38% erucic acid C 22 h 42 o 2 , 12% sodium carboxymethylcellulose NaCMC for subsequent use;

[0028] erucic acid C 22 h 42 o 2 Heating, heating erucic acid to 60 degrees in a beaker filled with physiological saline, and keeping it for 30 minutes;

[0029] The heated erucic acid C 22 h 42 o 2 Stand to cool, stand and cool to 20 degrees at room temperature;

[0030] The ratio of erucic acid to normal saline is 1:2;

[0031] Mix the spare sodium carboxymethylcellulose NaCMC and new anticoagulant C in sequence 19 h 16 o 6 N. Epinephrine C. 9 h 14 o 3 N, dihydrate C of oxytetracycline 22 h 26 N 2 o 11 Components, take a sufficient amount of the aforementioned erucic acid at a temperature of 2...

experiment example

[0040] The experimental recipients are Boer goats, and the experimental sheep are in good health;

[0041] During the operation, intramuscular injection of Jingsongling 0.1ml / 10kg body weight was used for anesthesia and Baoding, the abdomen was shaved, disinfected with iodine wine and alcohol and covered with a surgical towel;

[0042] Experimental injury: a series of incisions in the serosa and muscularis of the uterine horn extending into the endometrial cavity and multiple tears of the mucosa;

[0043] In practice, laparotomy is used to obtain embryos and transfer them, resulting in damage, from the uterine horn to the uterine body, and bleeding and adhesions occur during the operation;

[0044] After the operation, the abdominal cavity was closed in two layers, the peritoneum was sutured continuously, and the skin was sutured intermittently;

[0045] Recipients received penicillin and streptomycin injections after surgery.

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PUM

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Abstract

An anti-adhesion protector for accelerating coagulation of blood, decreasing the permeability of capillary blood vessels, and preventing bacterial attack is prepared from dihydrated terramycin (C22H26N2O11), acenocoumarol (C19H16O6N), erucic acid (C22H42O2), adrenine (C9H14O3N) and carb oxymethyl cellulose sodium (NaCMC).

Description

technical field [0001] The invention belongs to the field of veterinary surgical supplies, in particular to a pharmaceutical composition for resisting postoperative adhesion. Background technique [0002] Generally speaking, minor bleeding is unavoidable during or after surgery, and cell adhesion in the tissue will appear in the surgical area and the bleeding area, especially after abdominal surgery, the incidence of adhesion is 70-90%. Now in the animal husbandry and veterinary industry, it is an advanced method to use embryo transfer for more and better breeding of breeding sheep and cattle. If a sheep or cattle can accept several times of embryo transfer, it can improve the quality of breeding sheep and cattle. The reproductive rate of cattle, so rapid breeding is desired by the industry. However, the adhesions between the organs of the animal caused by the operation, such as the adhesion between the abdominal wall and the intestine, the omentum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/717A61P41/00
Inventor 冯建忠杨升张金龙
Owner TIANJIN CITY AGRI BIO TECH RES CENT
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