6results about How to "Reduce extravasation" patented technology

The invention discloses a transsclera continuous drug delivery device for eye disease treatment and a preparation method thereof. The device comprises an arc body, a wing-shaped fixing plate and a fixing band. A groove is formed in the bottom surface of the arc body; the two wing-shaped fixing plates are symmetrically arranged on the two sides of the arc body. The two wing-shaped fixing plates are respectively accommodated under the abdomen of the external rectus and under the abdomen of the lower rectus; the fixing belts are fixedly connected to the bottom face of the arc body, and gaps are formed between the fixing belts and the inner wall of the groove and used for storing medicine films; the ends, away from the arc body, of the two-wing-shaped fixing plates are spaced, and the arc body and the two-wing-shaped fixing plates are integrally in a C shape. The eye drops can be well attached to eyeballs, compression on the eyeballs is reduced, free rotation of the eyeballs is not affected, wearing comfort and medicine bioavailability are improved, medicine components are prevented from leaking to the keratoconjunctival surface and fascia tissue, medicine is prevented from going into blood pressure circulation through conjunctival blood vessels and lymphatic vessels, and the risk of side effects of the whole body is reduced; and toxicity and adverse reactions are reduced.

The invention relates to the field of biological medicine, in particular to application of demethyleneberberine in preparation of medicine for preventing or treating gout. In-vitro experiments show that the demethyleneberberine hydrochloride can inhibit RAW264.7 cell inflammation caused by monosodium urate crystals; in-vitro experiments show that the traditional Chinese medicine composition can relieve rat gout-like symptoms induced by MSU and relieve hyperuricemia induced by oteracil potassium combined with hypoxanthine. The result shows that the demethyleneberberine hydrochloride (DMB) can inhibit gout induced by monosodium urate crystals in the aspects of resisting inflammation and regulating uric acid metabolism, and the application range of the demethyleneberberine hydrochloride is widened.

The application discloses a kind of battery separators of chitosan aerogel microspheres and CNF composite and preparation method thereof, belong to lithium ion battery technical field.The battery separator includes polyolefin porous base film and the coating layer of at least one side surface of the base film;The coating layer is formed by coating and drying by coating slurry including chitosan aerogel microspheres and CNF;The chitosan aerogel microspheres are porous particles formed after chitosan is crosslinked, freeze-dried and crushed.The application constructs light, multistage pore structure coating layer by chitosan aerogel microspheres and CNF composite, significantly improves the wettability of electrolyte, liquid absorption rate and liquid retention rate of separator under the premise of extremely low weight gain, and has good thermal stability, effectively solves the contradiction that traditional ceramic coating weight and wettability cannot be compatible.

The utility model relates to the technical field of facial skin care, and discloses local mask cloth capable of loading wine paste fermentation liquor and a local mask. The local mask cloth is designed to only comprise a nose tip film cloth and a nasolabial fold film cloth which cover the nose tip and nasolabial folds, the local mask cloth comprises an outer covering layer, an upper liquid supplementing layer, a liquid storage layer, a lower liquid supplementing layer and a skin-friendly layer which are sequentially arranged from top to bottom, and anti-overflow pastes are arranged on the periphery of the local mask cloth; wherein mesh holes are distributed in the upper liquid supplementing layer, the lower liquid supplementing layer and the liquid storage layer, and the hole diameters of the mesh holes in the upper liquid supplementing layer and the lower liquid supplementing layer are smaller than the hole diameters of the mesh holes in the liquid storage layer. The mask cloth can better lock the essence, can reduce or avoid waste when the essence is taken out or applied, can better maintain the skin from the two sides of the nose wing to the two sides of the most mouth corner, and obtains a better use effect.

The application provides a red mud-based supercapacitor energy storage structure for road engineering application, and belongs to the technical field of road engineering and advanced building materials. The red mud-based supercapacitor comprises, from bottom to top, a first red mud-based composite electrode, a diaphragm and a second red mud-based composite electrode. The components of the first red mud-based composite electrode and the second red mud-based composite electrode comprise, by mass fraction, 40-60 parts of red mud, 10-15 parts of fly ash, 25-35 parts of cement, 5-15 parts of fine aggregate, 0.5-2 parts of Na2SO4 activator, 0.5-2 parts of conductive reinforcing material and 0.2-1 parts of reinforcing fiber. The first and second red mud-based composite electrodes are soaked in an electrolyte after initial setting, and the surface free liquid is removed after soaking and draining. The application adopts an electrode pore liquid absorption ion guiding mechanism, cancels the independent liquid electrolyte filling cavity in the existing road surface energy storage structure, and realizes the engineering configuration without free liquid electrolyte.

This invention discloses a flavoring process for spicy bean product strips, belonging to the field of food processing and bean product seasoning technology. The method first prepares a gated seasoning liquid containing an aqueous phase and a phase-change flavor-locking oil phase, ensuring the pH of the gated seasoning liquid is 6.0–6.6 under degassing and 4.4–4.9 under carbon dioxide pressure equilibrium. Then, the spicy bean product strip blanks and the gated seasoning liquid are placed in a pressure-vacuum circulating impregnation vessel, and a breathing-style flavoring cycle is sequentially performed, involving vacuuming, carbon dioxide pressure holding, rapid depressurization, and re-vacuuming. This causes the bean protein gel network to undergo a contraction-rebound gated change between the near-isoelectric point and degassing recovery stages, thereby forming an active pump to absorb flavor. After the cycle is completed, the mixture is cooled to below 25°C, causing the phase-change flavor-locking oil phase to gel in situ, locking in the fat-soluble spicy flavor.