Chinese medicine preparation for relieving cough, removing phlegm, relieving asthma and anti-inflammation

A traditional Chinese medicine preparation and expectorant technology, applied in the fields of anti-asthma, anti-inflammatory preparations, expectorants, and antitussives, can solve the problems of bitter taste, unfavorable patients, fishy taste, etc., and achieve the effect of increasing solubility

Active Publication Date: 2005-10-19
吉林省东北亚药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the preparation mouthfeel of these prior art productions is bitter and fishy, ​​is unfavorable for patient, especially the taking of children.

Method used

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  • Chinese medicine preparation for relieving cough, removing phlegm, relieving asthma and anti-inflammation

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0014] Take fresh chicken gall, peel the skin and extract the juice, concentrate the bile to 1 / 4 of the original volume, then add 3 times the amount of 90% ethanol for alcohol treatment, centrifuge, take the supernatant and recover the ethanol to relative density (20°C) 1.02-1.06 to get chicken gallbladder extract with chenodeoxycholic acid content of 10.5%; take 1 times the amount of cyclodextrin from chicken gall extract, add 8 times the amount of cyclodextrin to make it into a solution, add chicken The bile extract was stirred at 50°C for 5 hours, honey, sucrose, preservative sorbic acid, talcum powder and an appropriate amount of purified water were added, heated and boiled for 15 minutes, cooled and filtered to obtain an oral solution.

example 2

[0016] Get fresh chicken guts, peel the skin and get the juice, concentrate the bile to 1 / 3 of the original volume, then add 4 times the amount of 90% ethanol to carry out alcohol treatment, leave it for 24 hours, get the supernatant and reclaim the ethanol to a relative density ( 20 ℃) ​​1.10-1.20, namely get the chicken gall extract with 6.5% chenodeoxycholic acid content; get the cyclodextrin of 8 times the amount of the chicken gall extract, add 4 times the amount of cyclodextrin amount of water to make it into a solution , add chicken bile extract, grind at 30°C for 8 hours, dry to dryness under normal pressure at 90±5°C, and add appropriate amount of starch to obtain capsules.

example 3

[0018] Get fresh chicken guts, peel the skin and get the juice, concentrate the bile to 1 / 4 of the original volume, then add 5 times the amount of 90% ethanol to carry out alcohol treatment, leave it for 48 hours, get the supernatant and reclaim the ethanol to a relative density ( 20 ℃) ​​1.10-1.20, promptly get the chenodeoxycholic acid content and be the chicken gall extract of 8.5%; Get the cyclodextrin of 3 times amount of chicken gall extract, add 4 times of cyclodextrin amount water to make it become Add chicken gall extract to the solution, grind at 30°C for 8 hours, dry to dryness at 90±5°C under normal pressure, add sucrose and starch to granulate, then add appropriate amount of talcum powder, compress into tablets, and coat to obtain tablets.

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Abstract

The Chinese medicine preparation for relieving cough, removing phlegm, relieving asthma and anti-inflammation is prepared with chicken bile as material and through preparing chicken bile extractum containing chenodeoxycholic acid, including with medicinal cyclodextrin, and further making oral liquid, capsule or other preparation. Inclusion with cyclodextrin can mask the bitter and fishy smell for easing taking of patient, especially children patient, and can increase the water solubility of effective chicken bile components.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a preparation for relieving cough, eliminating phlegm, relieving asthma and reducing inflammation, which is prepared from chicken bile. Background technique [0002] Taking chicken gallbladder as a raw material to extract active ingredients to prepare a medicament for the treatment of upper respiratory tract infection is a known technology such as the chicken gallbladder oral liquid for the treatment of cough published by the patent application CN1149460A. However, the preparations produced by these prior art taste bitter and fishy, ​​which is unfavorable for patients, especially children, to take. Contents of the invention [0003] The purpose of the present invention is to overcome the shortcoming of prior art, provide a kind of Chinese medicine preparation with good mouthfeel and take chicken gallbladder as raw material. [0004] Antitussive, expectorant, antias...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K35/57A61P11/06A61P11/10A61P11/14
Inventor 冯祥苑敏廖晓燕张则刚石永伟权文杰
Owner 吉林省东北亚药业股份有限公司
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