Application of beta-Asarone in pharmacy

Abstract

The invention relates to the use of beta-asaricin in pharmaceutical industry, especially the use in preparing medicament for treating or preventing bronchial asthma, cough, phlegm, brain infarction, cerebral hemorrhage, apoplexy and epilepsy.

Description

technical field

[0001] The present invention relates to the use of β-asarone, in particular to the use in the field of pharmacy, especially to the use in the fields of medicines such as treating or preventing bronchial asthma, relieving cough and reducing phlegm, and treating encephalopathy. technical background

[0002] Shichangpu, a traditional Chinese medicine that eliminates phlegm and resuscitates, has certain pharmacological effects on the central nervous system, cardiovascular system, respiratory system, and digestive system. The main components of the volatile oil of Shichangpu are β-asarone (40-80%) and α-asarone (2-10%). At present, there are many studies on Shichangpu, and its monomer component β-asarone Ethers have been less studied. Studies have shown that Acorus shichangpu can protect cerebral cortex nerve cells and inhibit their apoptosis (Fang Yongqi, Kuang Zhongsheng, Xie Yuhui, etc. Effect of shichangpu on the apoptosis of nerve cells in rats with ischemia...

Examples

Embodiment 1

[0170] Get β-asarone 10g and Tween 5g, add polyethylene glycol and other drop pill bases to make drop pills containing β-asarone 1%.

Embodiment 2

[0172] Take 10g of β-asarone, 50g of Tween-80, and 90g of sodium chloride, add it to 1000ml of water, and make it into a 1% aqueous solution, heat to dissolve, mix well, put it into a medicine bottle, seal it, and sterilize it to make β-asarone - Injectable form of asarone.

Embodiment 3

[0174] Get 30g of β-asarone, 120g of Tween, 10g of sucrose, add water to make up to 1000ml, and configure it into a 3% aqueous solution. After mixing evenly, put it into a medicine bottle, seal it, and sterilize it into a product, an oral solution.

technical field

[0001] The present invention relates to the use of β-asarone, in particular to the use in the field of pharmacy, especially to the use in the fields of medicines such as treating or preventing bronchial asthma, relieving cough and reducing phlegm, and treating encephalopathy. technical background

[0002] Shichangpu, a traditional Chinese medicine that eliminates phlegm and resuscitates, has certain pharmacological effects on the central nervous system, cardiovascular system, respiratory system, and digestive system. The main components of the volatile oil of Shichangpu are β-asarone (40-80%) and α-asarone (2-10%). At present, there are many studies on Shichangpu, and its monomer component β-asarone Ethers have been less studied. Studies have shown that Acorus shichangpu can protect cerebral cortex nerve cells and inhibit their apoptosis (Fang Yongqi, Kuang Zhongsheng, Xie Yuhui, etc. Effect of shichangpu on the apoptosis of nerve cells in rats with ischemia...

Examples

Embodiment 1

[0170] Get β-asarone 10g and Tween 5g, add polyethylene glycol and other drop pill bases to make drop pills containing β-asarone 1%.

Embodiment 2

[0172] Take 10g of β-asarone, 50g of Tween-80, and 90g of sodium chloride, add it to 1000ml of water, and make it into a 1% aqueous solution, heat to dissolve, mix well, put it into a medicine bottle, seal it, and sterilize it to make β-asarone - Injectable form of asarone.

Embodiment 3

[0174] Get 30g of β-asarone, 120g of Tween, 10g of sucrose, add water to make up to 1000ml, and configure it into a 3% aqueous solution. After mixing evenly, put it into a medicine bottle, seal it, and sterilize it into a product, an oral solution.

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