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Dripping pills with mistletoe and Chinese angelica root and process for preparing the same

An angelica and dripping pill technology, applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of low dissolution rate, unfavorable improvement of patients' ability to seek medical treatment, increase in medication cost, etc., and achieve dissolution and absorption. Accelerates, improves bioavailability, increases the effect of total surface area

Inactive Publication Date: 2006-01-18
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In addition, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the quality of the drug. Efficacy also directly affects the therapeutic effect
At the same time, conventional oral dosage forms often produce relatively large dust pollution during the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.
The production process of conventional oral preparations is also relatively complicated, and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of Angelica Jisheng dripping pills of the present invention will be further described.

[0032] [Group 1: Trials with a single substrate]

[0033]1. Preparation of medicinal extract: according to [Preparation Method 1], pre-prepared extract dry powder containing 2 traditional Chinese medicine active ingredients such as angelica and mistletoe is ready for use;

[0034] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0036] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Angelica Jisheng Dropping Pills with different specifications.

[0037] [test r...

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PUM

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Abstract

The invention relates to a Chinese angelica parasitic drop pill, which is a medicinal composition for treating rheumatic arthritis, hypertrophy spondylitis, waist and knee strain, waist and legs pain, dysmenorrhea, ischialgia, and nerve cephalalgia. to provide a medicinal composition having the advantages of high biological availability, quick-speed medicine release, quick-speed effect, higher medicinal content, accurate administration dosage, low price, no acute allergic reaction or adverse effect, and facilitated transportation and carrying. The drop pill is prepared from the extract containing Chinese angelica and mistletoe, and medicinal carrying agent as the base material.

Description

technical field [0001] The invention relates to a kind of medicine which has the functions of relaxing muscles and collaterals, dispelling rheumatism and analgesia, and is often used for diseases such as rheumatoid arthritis, hypertrophic spondylitis, waist and knee strain, lumbago and leg pain, dysmenorrhea, sciatica, nervous headache and other diseases. The therapeutic pharmaceutical composition particularly relates to an oral preparation of a pharmaceutical composition prepared from extracts containing active ingredients of two traditional Chinese medicines such as angelica and mistletoe as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 -Danggui Jisheng Injection prepared by the preparation method given in B-3820-98 is a kind of medicine that has the functions of relaxing muscles and collaterals, dispelling rheumatism and analgesia, and is often used for rheumatoid arthritis, hypertrophic spondylitis, Pure traditional Chinese...

Claims

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Application Information

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IPC IPC(8): A61K36/232A61K9/20A61P29/00A61P19/02A61P15/00A61P25/02A61P25/04
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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