Titanium net with fimbrin and its prepn and application

A technology of silk fibroin and titanium mesh, applied in biochemical equipment and methods, medical science, microbiology, etc., to reduce complications, promote tracheal mucosal repair and clinical reconstruction of tracheal defects
CN1739809AInactive Publication Date: 2006-03-01AFFILIATED HUSN HOSPITAL OF FUDAN UNIV +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
Publication Date
2006-03-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention belongs to the field of tissue engineering and medical material technology, and is especially titanium net with fimbrin coating and its preparation process and application in reconstructing trachea default. The present invention prepares fimbrin-titanium net complex with medical titanium net as support material and fimbrin to form coating. Fimbrin has excellent biocompatibility and can promote the growth of fibroblast and mucosa cell, speed healing, reduce complications. Clinically, the present invention is used in repairing trachea default. The present invention is significant in the research of fimbrin in promoting repair of trachea mucosa, reconstructing trachea default and reducing complications during reconstructing trachea default.
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Description

technical field

[0001] The invention belongs to the field of tissue engineering and medical materials, and in particular relates to a silk fibroin-coated titanium mesh, a preparation method thereof and an application in tracheal defect reconstruction. Background technique

[0002] At present, when the body has extensive damage to the trachea due to inflammation, trauma, tumors or other lesions, and a long segment of the trachea is removed, the defective trachea needs to be repaired. For a long time, the problem of repairing tracheal cartilage defects has puzzled clinicians. One-stage end-to-end anastomosis is only suitable for the repair of local defects. When the length of the defect exceeds 6.0 cm, serious complications such as anastomotic leakage are likely to occur due to high anastomotic tension. The rapid development of tissue engineering technology has brought new hope to tracheal reconstruction, but there has been no breakthrough since the initial attempt in 1994. I...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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