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Six-medicine preparation and new preparing method

A technology for preparations and traditional Chinese medicine preparations, applied in the field of neurasthenia, can solve the problems of large dosage, many impurities, affecting clinical application, etc.

Inactive Publication Date: 2006-05-24
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] The preparation method of dropping pill of the present invention:

[0066] prescription:

[0067] Rehmannia glutinosa 384g Schisandra 192g Chinese yam 192g

[0068] Alisma 144g Moutan Cortex 144g Poria 144g

[0069] PEG4000 100g

[0070] Makes 1000 pills

[0071] Preparation:

[0072] (1) Get Schisandra chinensis, be ground into coarse powder (cross 40 mesh sieves), put IL supercritical CO 2 In the extraction kettle, adjust the pressure: 25MPa, temperature: 50°C, flow rate: 30kg / h, extraction time: 2h. Collect the extract; β-CD inclusion, the best process is: the ratio of β-CD to water is 1:8, the ratio of oil to β-CD is 1:6, sonicate for 40 minutes to obtain the inclusion compound;

[0073] (2) Take the prescribed medicinal materials, add water and decoct 3 times, 1 hour each time, combine the decoction, filter, and concentrate the filtrate to a certain volume; add 8 times the amount of 95% ethanol, stir evenly, stand still, and refrigerate for 12 hours , filter...

Embodiment 2

[0076] The preparation method of soft capsule of the present invention:

[0077] prescription:

[0078] Rehmannia glutinosa 1384g Schisandra 692g Chinese yam 692g

[0079] Alisma 519g Moutan Cortex 519g Poria 519g

[0080] PEG400 440g

[0081] Makes 1000 capsules

[0082] Preparation:

[0083] (1) Get Schisandra chinensis, be ground into coarse powder (cross 40 mesh sieves), put IL supercritical CO 2 In the extraction kettle, adjust the pressure: 25MPa, temperature: 50°C, flow rate: 30kg / h, extraction time: 2h. Collect the extract; β-CD inclusion, the best process is: the ratio of β-CD to water is 1:8, the ratio of oil to β-CD is 1:6, sonicate for 40 minutes to obtain the inclusion compound;

[0084] (2) Take the prescribed medicinal materials, add water and decoct 3 times, 1 hour each time, combine the decoction, filter, and concentrate the filtrate to a certain volume; add 8 times the amount of 95% ethanol, stir evenly, stand still, and refrigerate for 12 hours , filt...

Embodiment 3

[0087] The preparation method of granule of the present invention:

[0088] prescription:

[0089] Rehmannia glutinosa 1600g Schisandra chinensis 800g Chinese yam 800g

[0090] Alisma 600g Moutan Cortex 600g Poria 600g

[0091] Made into 1000g

[0092] Preparation:

[0093] (1) Take the prescribed medicinal materials, soak them with 75% ethanol for 60 minutes, then heat and reflux for extraction 3 times, each time for 1 hour, combine the extracts, concentrate under reduced pressure to form a thick ointment, and set aside;

[0094] (2) Combine the above active ingredients, add 5.0 g of aspartame and 250.0 g of dextrin, granulate, dry, and spray 5.0 g of essence to obtain 1000 g of granules.

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PUM

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Abstract

The present invention relates to a Chinese medicine composition and its preparation process. In particular, it relates to a Chinese medicine prescription for curing the diseases of neurasthenia, dizziness, cardio palmus, tinnitus, margins of eyelids and polyuria at night and its preparation process. Said Chinese medicine preparation can be made into dripping pills and soft capsule preparation.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription for neurasthenia, dizziness, palpitation, tinnitus and dizziness, and nocturia and the preparation process thereof. Background technique: [0002] Neurasthenia, dizziness, palpitations, tinnitus and dizziness, and frequent urination at night are common clinical symptoms. Traditional Chinese medicine often treats them by nourishing the liver and kidney, and the curative effect is remarkable. Liuwei Pill is its representative medicine. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the present invention can better collect the essence of the medicine and put it thickly, is easy to dissolve an...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/16A61K9/20A61K9/48A61P25/20
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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