Composition for veterinary and medical use

A composition and compound technology, applied in application, drug combination, active ingredient of heterocyclic compounds, etc., can solve problems such as weak antibacterial activity
CN1845738AActive Publication Date: 2006-10-11IRP健康私人有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
IRP健康私人有限公司
Publication Date
2006-10-11

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Abstract

The present invention relates to compositions for treating gastrointestinal disorders and related conditions, including irritable bowel syndrome; inflammatory bowel disease, colitis, Crohn's disease and / or promoting weight gain in animals including humans, said compositions Comprising berberine of general formula (1) or derivatives thereof (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and X are as defined in claim 1) and / or Polydialdehydes are selected from polydialdehydes such as dialdehyde polysaccharides, eg oxycellulose or oxystarch or poly(acrolein / acrylic acid).
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Description

Background of the invention

[0001] Gastrointestinal ("GI") dysfunction is caused by pathogen invasion, treatment with broad-spectrum antibiotics, improper diet, stressful lifestyle, and other pathogenic factors. This is a common disease with symptoms such as Intestinal Stress Syndrome (IBS), which is present in 20% of American adults. In Canada, IBS is the leading cause of absenteeism in schools and factories, second only to colds. So far, there is no good medicine for IBS and inflammatory bowel disease (IBD). A satisfactory therapeutic composition should meet the following conditions:

[0002] ●Non-toxic and safe to use.

[0003] ● Will not inhibit the probiotics in the internal organs or produce side effects on them.

[0004] ●Preferably has low oral bioavailability (no systemic effect).

[0005] ●No bacterial resistance.

[0006] ●Anti-inflammatory.

[0007] ●Stop diarrhea and inhibit secretion.

[0008] ●Anti-motility.

[0009] ●Enhance immunity.

[0010] ●Neutralize toxins. ...

Claims

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