Application of glycyrrhizic acid and glycyrrhetic acid in preparing medicine for inflammatory enteropathy

A technology for inflammatory bowel disease and glycyrrhetinic acid, applied in the application field of glycyrrhizic acid or glycyrrhetinic acid in the preparation of medicines for treating inflammatory bowel disease

Inactive Publication Date: 2006-10-18
WUHAN UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the effect of glycyrrhizic acid and glycyrrhetinic acid on prevent

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  • Application of glycyrrhizic acid and glycyrrhetic acid in preparing medicine for inflammatory enteropathy

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Embodiment Construction

[0011] The present invention is further illustrated by the following examples

[0012] Traditional Chinese medicine can often play an important role in the treatment of chronic and intractable diseases, with good curative effect, especially small toxic and side effects. In the present invention, glycyrrhizic acid and glycyrrhetinic acid are selected as medicines against inflammatory bowel disease, and the effects of glycyrrhizic acid and glycyrrhetinic acid on inflammatory bowel disease and the drug action mechanism are explored by establishing an animal model of inflammatory bowel disease. The aim is to select a drug with definite curative effect and low toxicity in anti-inflammatory bowel disease.

[0013] Wood invention revealed the effect and mechanism of glycyrrhizic acid and glycyrrhetinic acid on inflammatory bowel disease by establishing animal models of inflammatory bowel disease and other techniques.

[0014] Materials and Methods

[0...

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Abstract

The present invention relates to the application of glycyrrhizic acid and glycyrrhetic acid in preparing medicine for inflammatory enteropathy. Glycyrrhizic acid and glycyrrhetic acid possess the functions of inhibiting inflammation reaction and resisting oxidation, so that the medicine of glycyrrhizic acid or glycyrrhetic acid has high curative effect on inflammatory enteropathy, high safety and other advantages.

Description

technical field [0001] The invention relates to the application of glycyrrhizic acid or glycyrrhetinic acid in the preparation of medicines for treating inflammatory bowel disease. Background technique [0002] Inflammatory bowel disease (IBD) is a persistent disease that has plagued doctors and scientists for many years, mainly including ulcerative colitis (UC) and Crohn's disease (CD), the former is a Chronic non-specific colitis, ulceration or even canceration occurs in severe cases, the lesions mainly involve the colonic mucosa and submucosa, and the main clinical manifestations are diarrhea, abdominal pain and mucus, pus and blood in the stool, and the latter lesions can involve various parts of the gastrointestinal tract. The granulomatous inflammation is distributed in steps, and the main clinical manifestations are diarrhea, abdominal pain, fistula and systemic symptoms in different degrees. At the 10th European Gastroenterology Annual Meeting, Rod Mitchell, chairma...

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Application Information

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IPC IPC(8): A61K31/704A61K31/7048A61P1/00A61P1/04
Inventor 丁虹马瑶王黎付婷婷周惠萍项瑾刘颖王莹
Owner WUHAN UNIV
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