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Drop pills for treating headache, and preparation method

A medicine, the technology of angelica, applied in the field of medicine, can solve the problems of large side effects, palliative treatment, and reduced curative effect, and achieve the effects of stable quality, definite curative effect, and simple preparation

Inactive Publication Date: 2006-12-06
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many medicines for the treatment of headaches at home and abroad, and all of them can only treat symptoms, mainly for pain relief. Very few of them adopt surgery, but the effect is not ideal. Drugs will produce drug resistance and addiction, so this type of drug is not easy to take for a long time, and it cannot fundamentally solve the problem of headache
In addition, anxiolytics, antidepressants, sympathetic nerve inhibitors, calcium ion blockers, antiepileptic drugs, etc. are clinically used according to different etiologies. These drugs have relatively large side effects, and long-term use will gradually reduce the curative effect, resulting in The patient had to gradually increase the dose of the drug, and the more the drug was taken, the worse the headache was
There is Zhengtian Pill, a Chinese patent medicine, which is a combination of Chinese and Western medicines. Its mechanism is to promote blood circulation and remove blood stasis. It is also equipped with Western medicine analgesics. The curative effect is not exact, and it is difficult to achieve the goal of radical treatment.
At present, there are many traditional Chinese medicine preparations for treating headaches, but their main disadvantage is their slow onset of effect, which affects the quality of life of patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Proportionally take Angelica sinensis 6.75g, Chuanxiong 6.75g, Radix Paeoniae Rubra 5.4g, Rehmannia 5.4g, Goulia 13.5g, Caulis spatholobi 13.5g, Prunella vulgaris 13.5g, Cassia 13.5g, Mother-of-pearl 13.5g, Yuanhu 6.75g, Asarum 1.34g, the above medicines are boiled 3 times, 1 hour each time, combine the decoction, concentrate the appropriate amount, add 2 times the amount of ethanol, let stand for 24 hours for precipitation, take the supernatant and concentrate it to a relative density of 1.3~1.4 Paste, thick paste for use;

[0042] Take the above thick paste, heat it in a water bath to dissolve it, mix it evenly, add 2.5 times of the total extract of polyethylene glycol 6000, make the material uniform (80~95℃), drip into the cooled liquid at 75~85℃ Take it out in paraffin wax (6~8℃), make 1000 drop pills, wipe the paraffin wax, and get it.

Embodiment 2

[0044]Proportionally take Angelica sinensis 4g, Chuanxiong 4g, White peony root 2g, Rehmannia glutinosa 2g, Gou Teng 10g, Caulis spatholobi 10g, Prunella vulgaris 10g, Cassia seed 10g, Pearl mother 10g, Yuanhu 4g, Asarum 0.5g, and the above medicines are boiled 4 Time, 0.5 hours each time, combine the decoction, concentrate the appropriate amount, add 4 times the amount of ethanol, stand for 36 hours for precipitation, take the supernatant and concentrate it into a paste with a relative density of 1.1 to 1.2, drying or spray drying, and crushing to obtain Powder for use;

[0045] Take 10g of the above medicinal powder, heat it in a water bath to dissolve it, mix it evenly, add a mixture of 25g of polyethylene glycol 6000 and 10g of polyethylene glycol 4000, drop them into methyl silicone oil to make 1000 droplets, take them out, and wipe them. Immediately.

Embodiment 3

[0047] Take 9g of Angelica sinensis, 9g of Ligusticum chuanxiong, 8g of self-peony root, 8g of Rehmannia glutinosa, 15g of Goulia, 15g of Caulis spatholobi, 15g of Prunella vulgaris, 15g of Cassia seed, 15g of mother-of-pearl, 9g of Yuanhu, 2g of Asarum, and the above medicines are boiled 5 times. , 2 hours each time, combine the decoction, concentrate an appropriate amount, add 3 times the amount of ethanol, stand for 18 hours for precipitation, take the supernatant and concentrate it into a thick paste with a relative density of 1.2 to 1.45, and use the thick paste for later use;

[0048] Take the above thick paste, heat it in a water bath to dissolve it, mix it evenly, add 4 times the amount of polyethylene glycol 6000 melted at 60~110℃, mix the material evenly at 80~110℃, and drop it into vegetable oil after heat preservation to make 1000 drops Take out the pill and wipe off the condensing agent to get it.

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating headache is prepared from 11 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, white peony root, prunella spike, etc. Its preparing process is also disclosed.

Description

Technical field [0001] The invention relates to the field of medicine, in particular to a dripping pill for treating headaches using traditional Chinese medicine as a raw material and a preparation method thereof. Background technique [0002] Headache is a common symptom in daily life. Almost everyone will have headache in their life. The causes of headaches are many and varied. At present, there are many drugs for headache treatment at home and abroad, and all of them can only treat symptomatically, mainly for pain relief. A very small number of them are treated with surgery, but the effect is not satisfactory. The symptoms are not cured. The patients have repeated headaches and take analgesics for a long time. Drugs can produce drug resistance and addiction, so such drugs are not easy to take for a long time, nor can they solve the headache problem fundamentally. In addition, anti-anxiety agents, antidepressants, sympathetic nerve inhibitors, calcium ion blockers, anti-epilept...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/20A61P25/04A61K35/56A61K35/618
Inventor 李永强郑永锋
Owner TIANJIN TASLY PHARMA CO LTD
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