Nifuratel-nystatin vaginal effervescent-tablets

Abstract

The invention relates to a nifungin-canstat vagina effervescent tablet. Wherein, it uses nifungin and canstat, with acid-alkali adding system, and stuff or directly being compressed into tablet or particles then to be compressed into tablet, or uses macrogol to cover the alkali, then to be compressed into tablet. The invention uses the acid alkali system which will generate carbon dioxide gas when meeting water as slaking agent; therefore, the tablet will foam and slake when adsorbs water in vagina, to disperse the elements into vagina completely, as uterine cervix, etc.

Description

technical field [0001] The invention relates to a new dosage form of nifuratel-nystatin, in particular to a nifuratel-nystatin vaginal effervescent tablet. Background technique [0002] Nystatin is a well-known antibiotic with fungicidal activity, especially its effect on Candida fungi is more significant. Nifuratel is a nitrofuran derivative and a broad-spectrum antibiotic, especially for common pathogens of gynecological infections such as Gram-positive and negative bacteria, trichomonads, molds, chlamydia and mycoplasma. It has no inhibitory effect on beneficial bacteria Lactobacillus. There is no negative interaction between the two components. In order to treat the increasingly common mixed vaginal infections (Candida, Trichomonas and bacteria), the original organism cannot be diagnosed or can not be diagnosed in time, so as to prevent superinfection of mold As well as relapse after other drug treatments, both provided a more complete effect. [0003] At present, the...

AI Technical Summary

Problems solved by technology

[0003] At present, the dosage forms of nifuratel-nystatin include suppositories and vaginal soft capsules, and there are no vaginal effervescent tablets at home and abroad.