Medicine for treating osteoporosis and its preparation method

A technology for bone hyperplasia and medicine, which is applied in the directions of medicine combinations, medicine formulas, and medical preparations containing active ingredients, and can solve problems such as insufficient treatment effect.

Active Publication Date: 2007-03-14
桂林华润天和药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this plaster mainly has certain therapeutic effects on diseases such as fractures and bone injuries, but it is not good enough for diseases such as arthralgia and paralysis.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] 1) Pulverize 50 grams of Dinggongteng, 50 grams of ephedra, 50 grams of angelica, 50 grams of dried ginger, 50 grams of Angelica dahurica, 50 grams of Caulis japonica, 50 grams of frankincense, 150 grams of Panax notoginseng, 150 grams of turmeric, 150 grams of pepper, and 100 grams of Jinbuchang , to obtain mixed powder for subsequent use;

[0063] 2) The resulting mixed powder is put into 6 times its weight and 70% ethanol aqueous solution for reflux extraction for 3 times, extracting for 1 hour each time, filtering the extract, merging the filtrate, reclaiming the ethanol and concentrating the filtrate into Paste;

[0064] 3) add 150 grams of camphor, 30 grams of cinnamon oil, 150 grams of menthol and the gel matrix prepared by conventional methods by carbomer, glycerin, triethanolamine, water in the paste of gained, mix homogeneously, use conventional The gel preparation method is to prepare and subpackage to obtain the bone bone gel of the present invention.

Embodiment 2

[0066] 1) Grind 350 grams of Dinggongteng, 350 grams of ephedra, 350 grams of angelica, 350 grams of dried ginger, 350 grams of Angelica dahurica, 350 grams of Caulis japonica, 350 grams of frankincense, 150 grams of Panax notoginseng, 150 grams of turmeric, 150 grams of pepper, and 100 grams of Jinbuchang , to obtain mixed powder for subsequent use;

[0067] 2) The resulting mixed powder is put into 7 times its weight and 80% ethanol aqueous solution for reflux extraction for 6 times, each extraction for 0.5 hour, the extract is filtered, and the filtrates are combined, and the resulting filtrate reclaims ethanol and concentrates it into Paste;

[0068] 3) Add 30 grams of cinnamon oil, 150 grams of menthol and 900 grams of plaster matrix prepared by conventional methods from rubber and rosin in the resulting paste, mix well, prepare with conventional plaster preparation methods, and obtain this product Invented Gutong Plaster.

Embodiment 3

[0070] 1) Pulverize 50 grams of Dinggongteng, 50 grams of ephedra, 50 grams of angelica, 50 grams of dried ginger, 50 grams of Angelica dahurica, 50 grams of Caulis japonica, 50 grams of frankincense, 10 grams of Panax notoginseng, 10 grams of turmeric, 10 grams of pepper, and 5 grams of Jinbuchang , to obtain mixed powder for subsequent use;

[0071] 2) The resulting mixed powder is put into 5 times its weight and 90% ethanol aqueous solution for reflux extraction 4 times, the first extraction is 1.5 hours, and the second, third, and fourth extractions are each extracted for 0.5 hours. Filtrate, combine filtrate, the filtrate of gained reclaims ethanol and concentrates into paste;

[0072] 3) Add 50 grams of camphor, 1 gram of cinnamon oil, 50 grams of menthol and the aerosol base prepared by conventional methods from ethanol, oleic acid, trichlorofluoromethane, and trichlorodifluoromethane in the resulting paste , mixed evenly, prepared by a conventional aerosol preparation...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating osteoproliferation and process for preparation, wherein the medicinal composition comprises the following raw materials (by weight portion): Tripterygium wilfordii 50-350 parts, Chinese ephedra 50-350 parts, Chinese angelica root 50-350 parts, dried ginger 50-350 parts, root of Dahurain angelica 50-350 parts, futokadsura stem 50-350 parts, frank incense 50-350 parts, notoginseng 10-150 parts, curcuma longa 10-150 parts, pepper 10-150 parts, camphor 0-150 parts, oil of Chinese cinnamon 1-30 parts and menthol 0-150 parts.

Description

(1) Technical field: [0001] The invention relates to a medicine for treating hyperosteogeny; the invention also relates to a preparation method of the medicine. (two) background technology: [0002] Currently on the market, there are many kinds of drugs for the treatment of bone hyperplasia diseases such as joint pain, swelling, numbness, and poor flexion and extension, such as various oral analgesics and some hormone drugs for injection. Although oral drugs can play a certain role However, it is difficult to achieve the effect of curing the disease, and long-term medication is easy to stimulate the gastrointestinal tract, so it is not easy for patients with stomach problems to take; while the injection of drugs can only temporarily inhibit the development of the disease, and cannot make the patient fully heal, and long-term Injecting hormones will cause great harm to the human body; in contrast, various external drug dosage forms are more popular with patients. For example...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P19/10
Inventor 饶颖荣张延惠谭桂发胡克露陈宇峰
Owner 桂林华润天和药业有限公司
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