Bluish dogbane extract preparing method, and its medicinal preparation and use

Abstract

The present invention discloses a dogbane total flavone and its contained effective component hyperin, isoquercitrin and quercetin, etc. The present inention also discloses a preparation method of dogbane total flavone. Said method includes the following steps: using Chinese medicinal material dogbane as raw material, adding ethyl alcohol to make extraction, recovering ethyl alcohol to obtain alcoholic extract, dissolving said extract in boiling water, filtering, feeding the supernatant fluid into polyamide column, using water to make elution, then using ethyl alcohol to make elution, collecting eluent, recovering ethyl alcohol, vacuum drying to obtain dried dried extract, using colorimetry to determine dogbane total flavone content, and using said dried extract as medicinal effective component. Said dogbane total flavone content is up to above 50%.

Description

technical field

[0001] The invention belongs to the technical field of separation and purification of effective parts of botanical medicines, and can make the total flavonoid content of the effective parts of apocynum more than 50%, reaching the national standard of Class 5 traditional Chinese medicine raw materials.

[0002] Pharmacological activity of Apocynum apocynum, literature reports have anti-cerebral ischemic effect of total apocynum flavonoids, research on anti-aging effects, effects on blood sugar and renal function of alloxan mice Background technique

[0003] Commonly used extraction and separation processes are: alcohol extraction-water precipitation-ethyl acetate extraction method to obtain total flavonoids. These methods either cause a large loss of active ingredients or destroy the components, resulting in low yields of total flavonoids and high costs. Therefore, it is necessary to study a new simple and efficient extraction and separation method, which is s...

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