Liquid formulation for treating allergic rhinitis

A technology for allergic rhinitis and liquid preparations, applied to allergic diseases, medical preparations containing active ingredients, organic active ingredients, etc., can solve the problems of inability to generate local immune response, immune memory, etc., achieve rapid onset and easy to carry , The effect of simple preparation process

Inactive Publication Date: 2007-05-23
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional injection vaccines can only produce a systemic humoral immune response, but cannot produce a corresponding local immune response and long-term immune memory to the pathogen invasion site.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A liquid preparation for treating allergic rhinitis. When preparing 100 g of the liquid preparation: weigh 1.5 g of Tween 80, 5 g of Cremophor RH40, and 0.2 g of ethylparaben, put them into 60 g of distilled water, and heat to 60°C Cool naturally into an aqueous solution; dissolve 1.5g of perilla seed oil, 1g of borneol, and 2g of lauryl alcohol in 5g of propylene glycol, and slowly add to the above aqueous solution, stirring while adding, to obtain a clear and transparent liquid, and then add isopropyl alcohol in sequence Inosine 0.05g, uridine acid 0.5g, sodium metabisulfite 0.1g, add distilled water to a sufficient amount, mix evenly, subpackage, and sterilize to obtain 100g of liquid preparation for treating allergic rhinitis.

Embodiment 2

[0039] A liquid preparation for treating allergic rhinitis. When preparing 100 g of the liquid preparation: weigh 0.25 g of Tween 80, 15 g of Cremophor RH40, and 0.2 g of ethylparaben, put them into 60 g of distilled water, and heat to 60°C Cool naturally into an aqueous solution; dissolve 4.2g of perilla seed oil, 2g of borneol, and 1g of lauryl alcohol in 10g of propylene glycol, and slowly add to the above aqueous solution, stirring while adding, to obtain a clear and transparent liquid, and then add isopropyl alcohol in sequence Inosine 0.2g, uridine acid 0.1g, sodium metabisulfite 0.1g, add distilled water to a sufficient amount, mix, subpackage, and sterilize to obtain 100g of liquid preparation for treating allergic rhinitis.

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PUM

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Abstract

Disclosed is a liquid preparation for treating anaphylactic rhinitis, wherein the constituents include (by weight percent) purple perilla oil 1.5-4.2%, methyl glycol 5-10%, Tween80 0.25-1.5%, Cremophor RH 40 5-15%, borneol 1-2%, lauryl alcohol 1-2%, isopropyl inosine 0.05-0.2%, uridylic acid 0.10-0.5%, sodium metabisulfite 0.1%, Ethylparabenum 0.2% and balancing distilled water to 100%.

Description

technical field [0001] The invention relates to a medical preparation containing plant material, in particular to a liquid preparation for treating allergic rhinitis. Background technique [0002] Allergic rhinitis is a chronic inflammatory disease of nasal mucosal tissue mediated by IgE. During the pathological process, the participation of various inflammatory cells and the release of various mediators, cytokines and some inflammatory active substances in the nasal mucosa tissue play an important role in the occurrence and development of inflammation and the appearance of nasal symptoms. effect. Currently, commonly used drugs for the treatment of allergic rhinitis include antihistamines, corticosteroids, chromones, decongestants, and antileukotrienes. Among them, antihistamines act quickly, but have poor effect on nasal congestion; corticosteroids can inhibit the inflammatory response of nasal mucosa, but have slow onset and are not suitable for some people; chromones ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/535A61P11/02A61P37/08A61K31/7072A61K31/7064
Inventor 谢先吉饶跃峰谢方舟
Owner ZHEJIANG UNIV
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