Application of curcumin in preparing medicine for inventing drug resistance of malignant tumor

A technology of malignant tumors and curcumin, which is applied in the direction of anti-tumor drugs, drug combinations, non-active ingredients of polymer compounds, etc., to achieve the effects of low price, pain relief, and wide-ranging sources
CN1973834AInactive Publication Date: 2007-06-06CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
Publication Date
2007-06-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to the application of curcumin in preparing medicine for inverting drug resistance of malignant tumor. The malignant tumor includes oophoroma, cervix cancer, endometrial carcinoma, lung cancer, liver cancer, etc. The effective component of the medicine includes curcumin, demethoxy curcumin, didemethoxy curcumin or their mixture. The medicine consists of the effective component, solvent, stabilizer and co-solvent. It is used to act on drug resisting cell of malignant tumor alone or together with cisplatin or other chemotherapeutic medicine. Compared with traditional drug resistance inverting medicine preparation, the present invention has the advantages of small dosage, high safety and high efficiency.
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Description

technical field

[0001] The invention relates to the application of curcumin for preparing a drug-reversal drug for treating malignant tumor resistance, in particular to the application of curcumin for preparing a drug-resistant drug-reversal for treating ovarian cancer and other malignant tumors. Background technique

[0002] Chemotherapy is one of the main means of treating tumors. Multidrug-resistance (MDR) produced by tumor cells has become the main obstacle affecting the curative effect of tumor chemotherapy. According to relevant statistics, more than 90% of cancer patients die from multiple or multiple causes. Most of them are related to drug resistance, so finding low-toxic and effective MDR reversal agents is an important method to improve the efficacy of chemotherapy. At present, a variety of multidrug resistance reversal agents are in the basic and clinical trials. The reasons for drug resistance of tumor cells are complex, but the drug resistance protein produced...

Claims

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