Compound orally disintegrating tablet containing loratadine and ambroxol and preparation process thereof

Abstract

The invention relates to a luleitadingmione oral calving tablet which can treat allergic rhinitis, etc. wherein, it has quick adsorption, high biological utilization, and simple intake method without water. It uses Loratadine and bromamine acid as materials, with some findings.

Description

technical field

[0001] The invention relates to a compound loratadine ambroxol orally disintegrating tablet for relieving cough with abnormal secretions and related symptoms of allergic rhinitis, such as sneezing, runny nose, nasal itching, tearing, etc., and its preparation method. Background technique

[0002] Ambroxol hydrochloride is a new generation of respiratory mucus regulator, and it is also the most effective expectorant in clinical practice. It has excellent expectorant effect and can significantly promote the synthesis and secretion of alveolar surfactant. Ambroxol hydrochloride can stimulate bronchial mucus glands to secrete more flowable mucus, dilute sputum, reduce viscosity, and increase the production and secretion of pulmonary surfactant, thereby reducing airway resistance, reducing mucus adhesion, and activating Mucociliary blanket functions to facilitate mucociliary transport. Compared with the first-generation and second-generation expectorant drugs, ...