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Antiseptic wipes

a technology of wipes and wipes, applied in the field of personal skincleansing wipes, can solve the problems of long negative attributes, unqualified anti-microbial active ingredients of over-the-counter antimicrobial active ingredients, stinging injured or abraded skin, etc., and achieves no visible staining or discoloration

Inactive Publication Date: 2010-10-28
KELLY ALBERT R +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

"The present invention is about a special skin-cleaning wipe that can kill harmful bacteria and fungi. The wipe is made by soaking a dry cloth in a solution containing PVP-iodine and a surfactant. The cloth can be made from synthetic, woven, non-woven, or knitted fibers. When the wet cloth is rubbed on skin, it creates a foam that cleans the skin without leaving any stains or discoloration."

Problems solved by technology

Currently, there are only two over-the-counter antimicrobial active ingredients enjoying unqualified approval by the U.S. Food and Drug Administration for use in antiseptic skin cleansing, for first aid and wound cleansing, and in antifungal cleansing wipes.
However, there is a long list of negative attributes associated with the use of the ethyl alcohol.
It dries and irritates healthy skin and stings injured or abraded skin.
Moreover, as ethyl alcohol is highly volatile, it dissipates rapidly if not packaged in a proper barrier container.
Other disadvantages of ethyl alcohol include its stringent regulation by governmental agencies, its ability to erode some metals, its tendency to remove paint and varnish and to delaminate some plastics.
While elemental iodine has been used in antiseptic applications (U.S. Pat. No. 4,045,364), elemental iodine is known to possess a number of undesirable properties.
Free elemental iodine is highly toxic, irritative, sensitizing, odorous and it also causes stains and readily vaporizes due to sublimation.
But such wet wipes are expensive because they require barrier packaging to prevent evaporation or “dryout”.
Also contributing to the expense of such wipes is the need for special binder-free substrates for hydro-alcoholic formulations and starch-free substrates for aqueous iodophor formulations.
Thus, the use of these ingredients has been limited and reserved for higher risk healthcare and medical environments where other considerations justify the higher costs.

Method used

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  • Antiseptic wipes

Examples

Experimental program
Comparison scheme
Effect test

example # 1

[0040]Formulation # 1 listed below was impregnated into a 4.0 oz. / sq. yd. non-woven 100% polypropylene needle-punched fabric at a level of 22.7%-25.7% add-on of the web. Wipes of 8×11 inches were cut from the fabric and were prepared using the technique described in U.S. patent application Ser. No. 10 / 021,395.

Treatment of WipesWeight of wipes (g.)Add-on (g.)% add-on7.41.925.77.71.823.47.91.822.8

Formulation # 1Wt. PercentIngredients6.3%Povidone iodine 30%BIO-SOFT EA 10 (100% water-freeconcentration manufactured by Stepan)47.2% Propylene glycol 15%Glycerine1.5%Menthol fragrance

Evaluation

[0041]The treated antiseptic hand wipes were evaluated by wetting both hands with water under a running faucet. The wet hands were then rubbed with the dry wipe to activate the ingredients. The wipe foamed readily when activated with water from the wet hands. There was very little iodine odor detected, and the cleansing action of the wipe was quickly evident. There was no irritation and there was a lub...

example # 2

[0042]The 4.0 oz. / sq. yd. needle-punched 100% polypropylene 8×11-inch fabric was similarly impregnated with formulation # 2 listed below:

Formulation # 2Wt. PercentIngredients 5%Povidone iodine20%Glycerine20%Igepal Co-530 (100% water-free concentrationmanufactured by Stepan)53.5%  Propylene glycol1.5% Menthol fragrance

Treatment of WipesWeight of wipes (g.)Add-on (g.)% add-on7.71.114.27.71.316.8

Evaluation

[0043]A wipe was lightly moistened with water from a faucet. The wet wipe, which picked up 25 grams of water, was rubbed gently over the hands for one minute. The wipes foamed extensively as the hands were gently scrubbed with the wipe. No odor of iodine was detected. A lubricous feel was detected as the wipe was used on the hands. The wipe was then discarded and the hands were rinsed under water. No staining of the hands was observed and the hands felt smooth, soft and clean with a pleasant aroma. Based on the water pick-up of the wipe, the iodine concentration was about 220-PPM. Sub...

example # 3

[0044]1.5 oz. / sq. yd. thermo-bonded polypropylene fabric was cut into 8×10-inch wipes. Wipes were treated with formulation # 3 listed below:

Formulation # 3Wt. PercentIngredients58.0%Propylene glycol  25%Igepal CO-530 (100% water freeconcentration manufactured by Stepan) 5.0%Povidone iodine12.0%Glycerine

Treatment of WipesWeight of wipes (g.)Add-on (g.)% add-on2.50.5020.02.60.4015.432.60.5019.2

Evaluation

[0045]Hands were wet under a running faucet. A treated wipe was rubbed over the wet hands. Foaming was observed within seconds. The wipe was easy to manipulate through the hands and cleaned the hands thoroughly. After 30 seconds, the wipe was discarded and the hands rinsed under water. No staining of the hands was observed. Hands felt refreshed and soft. It could be demonstrated that the treatment solution was effective as an antimicrobial.

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Abstract

A personal skin cleansing wipe comprising a flexible substantially dry matrix formed from synthetic, woven, non-woven or knitted fibers impregnated with a substantially anhydrous antimicrobial, antiseptic, antifungal solution in an amount wherein the matrix retains its substantially dry characteristics and the treatment solution includes an amount of PVP-iodine as active in solution in glycol and or glycerin. The treatment solution, in addition to an effective amount of PVP-iodine as active, contains surfactants, preferably Tego® Betaine CK D, and optionally a compatible fragrance and / or moisturizer. The wipe is activated with water just prior to use.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application is a continuation-in-part of application Ser. No. 12 / 589,820 filed Oct. 30, 2009, which in turn is a continuation-in-part of application Ser. No. 11 / 118,197 filed May 2, 2005.FIELD OF INVENTION[0002]The present invention relates to a personal skin-cleansing wipe incorporating a non-aqueous solvent, a surfactant, and an antimicrobial / antifungal / antiseptic component. The wipe contains PVP-iodine as active component which is incorporated in substantially anhydrous form. The wipe is activated by the addition of water before use and residual debris, including PVP-iodine remaining on the skin following use is removed by rinsing with water. The structure of the wipe should preferably comprise synthetic fibers. The wipe can be used as an antiseptic hand washcloth, an antifungal body or skin wipe or for first aid or wound cleaning, among other applications.BACKGROUND OF THE INVENTION[0003]It is well known that topical skin surfaces...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A01N43/36A01N25/08A01P1/00B05D5/00A61L2/18
CPCA61K33/18Y10T442/2525Y10T442/2918
Inventor KELLY, ALBERT R.SAFERSTEIN, LOWELL
Owner KELLY ALBERT R