Cosmetic

a technology of cosmetics and ingredients, applied in the field of cosmetics, can solve the problems of chemical improvement of skin quality, lack of long-term effect of cosmetic formulations, and technical challenges, and achieve the effect of promoting skin rejuvenation

Inactive Publication Date: 2013-12-19
RESTORSEA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0006]A composition is provided that includes a fish spawn protein isolate having an anti-inflammatory effect on mammalian skin. A natural product extract is also present that includes unsaturated fatty acids and sterols. The natural product extract has anti-oxidant activity. An emulsifier or a solubilizer, or a combination thereof is provided to form a mixture of the isolate and the extract. A composition is also provided that includes an egg hatching protein isolate having an anti-inflammatory effect on mammalian skin. At least one biocide protective of activity of the egg hatching protein isolate for 3 months storage at 20° C. is present while the activity when applied to subject skin after storage remains within 80% of unformulated and freshly isolated protein. An emulsifier forms a mixture with the egg hatching protein isolate that has an aqueous phase buffered to a pH of between 5.6 and 7.9. A kit is provided inclusive of an aforementioned composition in a non-sterile, multi-use package along with instructions for the application thereof to skin to promote skin rejuvenation.

Problems solved by technology

Other components conventional to cosmetic compositions are emollients that convey appreciable quantities of water to the skin that in combination with oils affects the amount of moisture released or retained from skin to mask wrinkles Unfortunately, such conventional cosmetic formulations have failed to afford a long term, chemical improvement of skin quality.
Additionally, while the inclusion of such fish spawn isolate proteins in cosmetics has been contemplated, the ability to maintain protein activity and afford storage stability in a cosmetic formulation represents a technical challenge.

Method used

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  • Cosmetic
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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0026]A cosmetic cream is prepared after formulating the three phases. Phase A is heated to 75-80° C. with sufficient mixing to form a homogenous mixture. Phase B is premixed in a separate vessel at ambient temperature and added to Phase A at 40° C. or lower temperature. Phase C is added to the now combined A and B Phases mixture in order with sufficient mixing until a homogenous cream is formed. A homogeneous and storage stable cream results.

example 2

[0027]A cosmetic cream in which the fish spawn protein isolate and a natural product extract are components of Phase A is provided instead of the fish spawn protein isolate and the natural product extract present in a separate Phase C per Example 1. With Phase A being formed at ambient temperature to avoid protein denaturation, a like cream is obtained.

example 3

[0029]Fresh, unfertilized salmon (Salmo salar) eggs harvested from females in reproductive phase (late fall) are kept on ice, and the extract preferably made immediately. It is possible to freeze dry eggs in a cryoprotectant (e.g., 1.5 M 1,2-propanediol and 0.2 M sucrose) without disrupting the egg membrane. Freezing should be gradual (−1° C. / min) to −80° C. Eggs should be thawed and kept on ice throughout the extract preparation procedure.

[0030]Eggs are washed twice in HBSS or seawater with protease inhibitors (10 μg / ml). The washing solution is removed and the eggs are lysed and homogenized in a pre-chilled Dounce glass-glass homogenator. The lysate is transferred to Beckman Ultra Clear polymer centrifuge tubes (5 ml) while avoiding transfer of egg shells, and centrifuged for 15 min at 15,000 g at 4° C. in a Beckman ultracentrifuge using SW55T1 rotor. Three fractions are thereby obtained; lipid top fraction, cytoplasmic middle fraction, and a bottom fraction containing eggshells a...

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Abstract

A composition is provided that includes a fish spawn protein isolate. A natural product extract is also present that includes unsaturated fatty acids and sterols. An emulsifier is provided to form a mixture of the isolate and the extract. A composition is also provided that includes an egg hatching protein isolate and at least one biocide protective of isolate activity. An emulsifier forms a mixture with the isolate that has an aqueous phase buffered to a pH of between 5.6 and 7.9. A process of producing such a cosmetic has an emulsion or an aqueous phase that is buffered to a pH of between 5.5 and 7.9 prior to the addition of isolate to the emulsion. A process of improving skin appearance is provided that includes the application of the cosmetic to the skin at least three times per week to achieve the improvement of the skin appearance.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation application of U.S. Application Ser. No. 13 / 904,501 filed May 29, 2013, which is a continuation-in-part of PCT Application Serial Number PCT / US2013 / 022728, filed Jan. 23, 2013; that in turn claims priority benefit of U.S. Provisional Application Ser. No. 61 / 589,592, filed Jan. 23, 2012 the contents of which are hereby incorporated by reference.FIELD OF THE INVENTION[0002]The present invention in general relates to the cosmetic and components thereof, and in particular to a cosmetic containing egg hatching proteinaceous extracts and formulations thereof that are useful to enhance skin quality.BACKGROUND OF THE INVENTION[0003]Traditional cosmetic formulations have included oils and various lipophilic substances that formulate a protective coating on skin to mitigate weathering effects. The inclusion of a sunblock in a cosmetic also mitigates ultraviolet damage to the skin associated with aging and free rad...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/97A61K8/92A61Q19/00A61K8/66A61K8/64
CPCA61K8/97A61K8/66A61K8/64A61Q19/00A61K8/92A61K8/361A61K8/63A61K8/987A61K8/99A61Q19/08A61K8/9711A61K8/9717A61K8/9789A61P17/00A61K35/60A61K8/922A61K8/34A61K8/37A61K8/676A61K8/73A61K2800/48A61Q19/007
Inventor ALABATA, ENRIQUE P.PAO, PATRICIA S.
Owner RESTORSEA
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