The invention relates to an ergonomic anti-deformation sole, which relates to the technical field of sole structures, and comprises a wrapping pad, a heightening pad mounted on the wrapping pad, filling pads mounted on the lower side of the wrapping pad, a flow
communication layer mounted between the filling pads, and a bottom non-slip pad mounted on the lower sides of the filling pads and the flow
communication layer, an
air cushion layer sole is mounted on the outer contour of the bottom-layer non-slip mat, and the
air cushion layer sole and the filling mat are mounted together; according to the anti-deformation sole conforming to the ergonomics, in the walking process, the wrapping pad, the
air cushion layer sole and the bottom-layer anti-skid pad are extruded by the foot sole and the ground in a two-way mode, and the air
cushion layer sole installed on the edge of the sole and the bottom-layer anti-skid pad higher than the bottom face of the air
cushion layer sole make contact with the ground together; in the walking process, the air
cushion layer sole and the bottom non-slip mat make contact with the ground gradually from the sole to the
toe, then the air cushion layer sole is squeezed gradually in the walking process, and after the air cushion layer sole is squeezed, the squeezing air cushion is squeezed synchronously.