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86 results about "Clicker" patented technology

A clicker, sometimes called a cricket, is any device that makes a clicking sound, usually when deliberately activated by its user. They usually consist of a piece of thin metal or plastic held in a casing so that the metal is slightly torqued; depressing one end of the metal causes it to pop out of alignment and releasing it causes it to pop back into alignment, each time making a sharp click.

Medication injector apparatus with drive assembly that facilitates reset

A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting.
Owner:ELI LILLY & CO

Precious metal/paramagnetic metal composite nanoparticle with core-shell structure and application thereof

The invention discloses a precious metal/paramagnetic metal composite nanoparticle with a core-shell structure and application thereof. A preparation method for the precious metal/paramagnetic metal composite nanoparticle comprises the following steps: (a) preparing a precious metal nanoparticle with a particle size of 5 to 50 nm, wherein the precious metal is gold or silver; (b) taking a compound A containing a mercapto group and an amino group, allowing the precious metal nanoparticle to react with the compound A so as to obtain a product a and then allowing the product a to react with methyl acrylate so as to obtain a product b; (c) taking a compound C containing an azido group and an amino group and reacting the product obtained in the step (b) with the compound C so as to obtain an azido-surface-modified precious metal nanoparticle; (d) subjecting the azido-surface-modified precious metal nanoparticle prepared in the step (c) and a micromolecular ligand containing an alkynyl group to the Clicker reaction so as to obtain a product d; and (e) reacting the product d with a chloride of a paramagnetic metal so as to obtain the composite nanoparticle. The precious metal/paramagnetic metal composite nanoparticle can be used as an MRI and CT enhancement contrast agent.
Owner:WENZHOU UNIVERSITY

Foot controlled computer mouse with finger clickers

A device for generating and delivering control signals to a computer has a housing with a top foot engaging surface on a top portion. Roller bearings captivated between the top portion and a base portion are disposed in moving engagement with a plate, thereby allowing the user's foot to move the top portion relative to the base. Optical sensors detect movement of the top portion and transmit electrical signals to a microcontroller which interprets the linear directional movement relative to X and Y coordinates. The user's foot is selectively moved over either a left or right light sensor to perform left and right mouse click operations. An external RCA jack allows for attachment of external cursor control devices, such as hand or finger operated mouse click controls. In one embodiment, magnetic switches are provided in a keyboard to perform left and right click operations, wherein a magnetic ring worn on the hand of the user is selectively passed over either a left or right magnetic switch to perform the left or right click operation. In an alternative embodiment, magnetic switch devices are worn on a finger of the left and right hands and magnetic rings worn on the thumbs are used to selectively perform the left and right click operations by moving the magnetic ring on either the left or right hand in close proximity to the magnetic switch worn on the same hand.
Owner:MEDINA CARLOS A
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