12 results about "Matrix cell" patented technology

The invention provides a methacrylic anhydride modified sclera extracellular matrix repair material and a curing method thereof, and belongs to the technical field of medical repair materials. The methacrylic anhydride modified sclera extracellular matrix repair material provided by the invention is prepared from the following raw materials: a methacrylic anhydride modified sclera extracellular matrix, methacrylated gelatin, a photoinitiator and a solvent. The sclera extracellular matrix modified by methacrylic anhydride is adopted, methacrylic anhydride contains methacrylic acid, double bonds can be introduced, the sclera extracellular matrix has the photo-initiation polymerization capacity, and in-situ gelling can be carried out at sclera and cornea damage positions under the action of a photoinitiator; the sclera extracellular matrix has good biocompatibility and histocompatibility, so that sclera matrix cells and corneal epithelial cells are adhered and proliferated, and the sutureless repair is realized; the methacrylated gelatin can provide a photo-crosslinking gelatin network under the action of a photoinitiator, so that cell adhesion and proliferation can be promoted, and repair is realized.

The invention discloses a bionic photo-thermal nano motor for targeted regulation and control of a solid tumor matrix-immunosuppression microenvironment and a preparation method and application thereof, and belongs to the technical field of biomedical materials.The preparation method comprises the steps that polydopamine nanoparticles and a K2PtCl4 aqueous solution are subjected to condensation reflux, and asymmetric PDA-Pt is prepared; and preparing a cancer-related fibroblast and breast cancer cell fusion membrane and coating the surface of PDA-Pt with the cancer-related fibroblast and breast cancer cell fusion membrane. The nano-motor realizes dual targeting of matrix cells and tumor cells through a surface modified fusion cell membrane, targeted ablation CAFs regulates and controls a tumor matrix microenvironment, a good tumor permeation effect is realized by cooperating with H2O2 responsive self-driving of the nano-motor, a mild photo-thermal-catalytic synergistic effect is formed by a photo-thermal effect of PDA and peroxidase-like activity of Pt nano-enzyme, and a good tumor permeation effect is achieved. And finally, the tumor immunosuppression microenvironment is remarkably improved, and the tumor immunotherapy effect is improved.

This invention discloses a lactate reactor capable of inhibiting intervertebral disc degeneration and its preparation method. The lactate reactor is an injectable gel microsphere loaded with lactate-catalyzing nanoparticles and matrix cell-derived factor SDF-1α. The lactate-catalyzing nanoparticles are mesoporous silica nanoparticles, whose mesopores are coated with lactate dehydrogenase, nicotinamide adenine dinucleotide, alanine aminotransferase, and glutamate, and whose surface is coated with an oxidized sodium alginate layer via a Schiff base reaction. This invention can efficiently convert pathological lactate in the nucleus pulposus microenvironment into alanine, which inhibits degeneration, while simultaneously recruiting stem cells to synergistically inhibit the process of intervertebral disc degeneration.

The present invention discloses a matrix-arranged power MOS transistor and a PMOS rectangular cell layout thereof. The power MOS transistor includes multiple groups of repeatedly arranged PMOS matrix cells, and the PMOS rectangular cells are adjusted to the number of repetitions according to the magnitude of the current required by external components. Each group of PMOS cells contains a gate, a source, and a drain. The drains and sources of adjacent two groups of PMOS matrix cells are connected, and the gates and sources are connected. According to different magnitudes of the current required by external components, the arrangement number of PMOS can be adaptively adjusted to meet the applications of the power MOS transistor in different scenarios, without the need to re-design the power MOS transistor as a whole.

The invention discloses a dot matrix cell element structure with high impact resistance and efficient thermal management and application thereof, the dot matrix cell element structure comprises a first hollow pipe, two ends of the first hollow pipe end at a virtual boundary of the dot matrix cell element structure, and the axial direction of the first hollow pipe is not parallel to the normal direction of each surface of the virtual boundary; the second hollow pipe is arranged inside the first hollow pipe in the radial direction, the second hollow pipe and the first hollow pipe are arranged at intervals in space, and the outer surface of the second hollow pipe is not intersected with the virtual boundary; and the plurality of connecting rib plates are connected between the first hollow pipe and the second hollow pipe. Compared with a traditional metamaterial structure, the metamaterial structure has the advantages of being larger in heat exchange area, higher in heat dissipation efficiency and even in load transmission. Correspondingly, the invention further provides a dot matrix material which is formed by periodically repeating the dot matrix cell element structure in a three-dimensional space. A box body of the battery box is at least partially made of the dot matrix interlayer material.

Systems and methods for simulating subterranean regions with fracture geometries. Using a microprocessor to receive simulator data including matrix grid data and fracture data; produce a matrix grid using the simulator data; identify geometric interactions between fractures and matrix cells; create new fracture cells; assign physical properties to new created fracture cells; identify geometric relationships between new created fracture cells and between new created fracture cells and matrix cells, including i) non-neighboring connections between new created fracture cells and matrix cells; ii) non-neighboring connections between new created fracture cells corresponding to individual fractures; and iii) non-neighboring connections between intersecting new created fracture cells; calculate thermal variances between created fracture cells and matrix cells, including determination of multi-phase fluid flow; create a data set associated with the thermal variances for simulator input, including digital keywords to generate a second digital output for visual display of a simulation accounting for thermal variances.

The invention provides a primer pair for rotavirus detection, a kit, application and a detection method for virus titer of an attenuated live vaccine. MA-104 cells cultured by a 5%-10% bovine serum DMEM (dulbecco's modified eagle medium) culture solution are used as a cell matrix, rotaviruses are activated and then inoculated into matrix cells for virus culture, and virus liquid is harvested according to cytopathic effects after the virus culture is performed for 2-7 days. According to the five designed primer and probe combinations, rotavirus RNA of different serotypes in a sample is amplified through a specific one-step reverse transcription real-time fluorescent quantitative polymerase chain reaction, positive and negative judgment of the serotypes is carried out, and the virus titer is calculated according to a Reed-Muench method. The kit comprises five primer and probe combinations which respectively have specificity on G1 serotype VP7 protein, G2 serotype VP7 protein, G3 serotype VP7 protein, G4 serotype VP7 protein and G9 serotype VP7 protein in the pentavalent rotavirus vaccine, and have no cross reaction.

Matrix cells are used for regeneration in an electrolyzer system. The electrolyte is electrolyzed in the matrix cell. Gas (predominantly product gas) which has unwantedly accessed the electrolyte space is transported off from the electrolyte space into the gas space envisioned therefor by a degassing device. Additional measures such as ultrasonic transducers and field electrodes may realize electrolyte flow and improved transporting-off of gas. A pump may be used to move the electrolyte, and the pump may move the electrolyte by generating bubbles.

The invention discloses a report data entry method, device and equipment, a medium and a product, and relates to the technical field of data acquisition. The method comprises the following steps: firstly, receiving a selection operation of a user on a target data cell in at least one report and a selection operation of the user on at least one target filling organization, and then generating a data concentration operation interface in response to the two operations, the interface comprises a data input matrix formed by taking the selected filling organization as a row and the selected data cell as a column, then receiving data entry operation of a user on the matrix cell through the operation interface, and finally synchronizing the entry data to an original cell of a corresponding report of the corresponding filling organization. Therefore, cross-report and cross-organization data self-defined range selection and centralized data entry can be realized, the report compiling and data filling efficiency of a group-type enterprise is remarkably improved, and practical application and popularization are facilitated.

Embodiments of the present application provide a RefSPAD matrix opening method and related equipment for calculating valid RefSPAD matrix cell combinations. The method comprises: acquiring the number of photons received by each SPAD cell in the RefSPAD matrix; inputting the number of photons of all SPAD cells into a preset calculation model to determine whether there is a SPAD cell combination that meets a photon number threshold; and if so, determining that the SPAD cell combination is a SPAD that needs to be opened.

The invention relates to a geometric boundary consistency strategy-based mixed dot matrix cell element filling method, which comprises the following steps of: acquiring a data set of cell elements based on an implicit expression model of a cell element structure; wherein the data set comprises configuration data, geometric parameters and mechanical property data of cell elements; constructing a diffusion model, and training the diffusion model by using the data set; acquiring mechanical distribution data of the cell structure; and inputting the mechanical distribution data into the trained diffusion model to obtain the cell configuration and geometric parameters of the dot matrix cell filling structure. According to the method, a model guiding strategy based on the minimization of the consistency variance function is provided, an independent guiding regression device is trained, and the model has obvious performance advantages in generalization performance and cell structure mechanical performance compared with a common neural network model and a variable density topological optimization method at present.

Matrix cells are used to improve the regeneration capacity of an electrolyzer system. The electrolyte is electrolyzed in the matrix cell. Gas (predominantly product gas) which has unwantedly accessed the electrolyte space is transported off from the electrolyte space into the gas space envisioned therefor by a degassing device. Additional measures such as ultrasonic transducers and field electrodes may realize electrolyte flow and improved transporting-off of gas.