2 results about "Matrix cell" patented technology

This invention discloses a lactate reactor capable of inhibiting intervertebral disc degeneration and its preparation method. The lactate reactor is an injectable gel microsphere loaded with lactate-catalyzing nanoparticles and matrix cell-derived factor SDF-1α. The lactate-catalyzing nanoparticles are mesoporous silica nanoparticles, whose mesopores are coated with lactate dehydrogenase, nicotinamide adenine dinucleotide, alanine aminotransferase, and glutamate, and whose surface is coated with an oxidized sodium alginate layer via a Schiff base reaction. This invention can efficiently convert pathological lactate in the nucleus pulposus microenvironment into alanine, which inhibits degeneration, while simultaneously recruiting stem cells to synergistically inhibit the process of intervertebral disc degeneration.

Embodiments of the present application provide a RefSPAD matrix opening method and related equipment for calculating valid RefSPAD matrix cell combinations. The method comprises: acquiring the number of photons received by each SPAD cell in the RefSPAD matrix; inputting the number of photons of all SPAD cells into a preset calculation model to determine whether there is a SPAD cell combination that meets a photon number threshold; and if so, determining that the SPAD cell combination is a SPAD that needs to be opened.