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6 results about "Peripheral thrombosis" patented technology
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Thrombosis is generally defined by the type of blood vessel affected (arterial or venous thrombosis) and the precise location of the blood vessel or the organ supplied by it. Deep vein thrombosis (DVT) is the formation of a blood clot within a deep vein. It most commonly affects leg veins, such as the femoral vein.
5 / 8 / 5 chitin diterpenoid compound, biosynthetic gene cluster and application of biosynthetic gene cluster
The invention discloses a 5 / 8 / 5 chitosan clostridium diterpenoid compound, a biosynthetic gene cluster and application of the biosynthetic gene cluster, and relates to the technical field of biological medicines. A 5 / 8 / 5 chitin type diterpenoid biosynthetic gene cluster Thm in trichoderma harzianum is identified through a genome mining system, chitin diterpenoid compounds with diversified structures are obtained by means of heterologous expression, the obtained compounds are subjected to anti-thrombotic activity comprehensive evaluation, and the result shows that the compounds 6 and 31 can obviously inhibit vascular thrombosis, the compound 6 has a remarkable inhibition effect on collagen-induced platelet aggregation, and the compound 31 has a better inhibition capability on thrombin-induced platelet activation. The compounds 6 and 31 show powerful antithrombotic effects in artery, vein and pulmonary artery thrombosis models, so that powerful technical support is provided for development of antithrombotic drugs.
Owner:HUAZHONG UNIV OF SCI & TECH
Energy delivery systems and uses thereof
Provided herein are devices, systems, and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, devices, systems, and methods are provided for delivering energy to difficult to access tissue regions (e.g. central or peripheral lung tissues), and / or reducing the amount of undesired heat given off during energy delivery.
Owner:NEUWAVE MEDICAL INC
Compositions and methods for detecting and treating thrombosis and vascular plaques
PendingCN120919356AEchographic/ultrasound-imaging preparationsSolution deliveryDiseaseVascular thrombosis
The present invention provides nanodroplets labeled with targeting ligands that can be used to detect and treat vascular thrombosis (e.g., fibrin clots) and vascular plaques, or related diseases and disorders, as well as methods of making and using the same.
Owner:MICROVASCULAR THERAPEUTICS LLC
SYSTEM FOR PREVENTING VASCULAR PLAQUE RUPTURE OR DETACHMENT THAT LEADS TO A STROKE AND / OR IS CAPABLE OF PREVENTING VASCULAR THROMBOSIS
Owner:ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (APHP) +3
Energy delivery systems and uses thereof
Provided herein are devices, systems, and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, devices, systems, and methods are provided for delivering energy to difficult to access tissue regions (e.g. central or peripheral lung tissues), and / or reducing the amount of undesired heat given off during energy delivery.
Owner:NEUWAVE MEDICAL INC