4results about How to "Highly repeatable" patented technology

This invention belongs to the field of photocatalyst materials technology, specifically relating to a three-dimensional graphene aerogel photo-self-propelled Fenton catalyst, its preparation method, and its application. The preparation method includes: mixing a graphene dispersion containing ethylenediamine with a phenolic resin prepolymer containing ferrocene, phenols, and an alkaline catalyst; followed by a one-step hydrothermal reaction, washing, and freeze-drying to obtain the three-dimensional graphene aerogel photo-self-propelled Fenton catalyst. This catalyst can be used to degrade organic pollutants in water under visible light irradiation.

The present application provides a crystalline form of tolebrutinib, an amorphous form, and a method of preparation thereof and a use thereof, and the crystalline form of tolebrutinib provided in the present application has at least one of the following advantages: good stability, low moisture attraction, uniform particle size distribution, solubility meeting the requirements for medicinal use, stable storage, avoiding phase transformation of the drug in the process of development and in storage, and a reliable method for the preparation thereof, which has a great development value. The amorphous form of tolebrutinib provided in this application, while possessing better solubility than that of tolebrutinib in the crystalline state, still possesses good stability of placement and acceptable hygroscopicity, and has high medicinal value.

The application discloses a method for synthesizing 2,5-disubstituted pyrroline by a three-enzyme co-immobilization system, and adopts a one-pot cascade biocatalysis method to synthesize 2,5-disubstituted pyrroline. The co-immobilized enzyme obtained by co-immobilizing L-amino transferase, L-lactic acid dehydrogenase and glucose dehydrogenase on an amino resin ESQ-3 is used as a catalyst for a synthesis reaction, and a deep eutectic solvent formed by betaine and glucose is added to a synthesis system. The co-immobilized enzyme is prepared by a method that L-amino transferase is first immobilized on the amino resin ESQ-3, and then L-lactic acid dehydrogenase and glucose dehydrogenase composite particles obtained by ammonium sulfate precipitation are continuously immobilized. The synthesis method can obtain a higher stable conversion rate, and a product is easier to separate and purify. Enzymes and coenzymes are efficiently recycled, regenerated and reused. In addition, a reaction medium added with the deep eutectic solvent has a significant positive effect on solubility of a substrate, stability of the enzyme and mass transfer of the system, so that an immobilized enzyme method catalytic synthesis reaction system suitable for industrial application is effectively constructed.

The invention provides a growth method of a metal halide single crystal film, which comprises the following steps of: firstly, depositing a layer of blended polymer film with an orthogonal dissolution characteristic on the surface of a metal halide single crystal substrate as a sacrificial layer, and performing solvent treatment to form a self-patterning soft template; and then coating the polymer layer with a precursor solution of a target epitaxy, carrying out nucleation, transverse growth and grain combination to form a uniform and compact single crystal thin film, and completing mechanical stripping and transfer of the epitaxial thin film through a thermal stripping adhesive tape. The growth method provided by the invention has excellent universality, can grow various metal halide single crystal films including lead-based, non-lead-based, alloy and superlattice structures, and has wide adjustability in size and thickness; in addition, the prepared thin film shows high carrier mobility and low trap density which are equivalent to those of blocky single crystals.