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Pedunculate herpetospermum seed extract, its dripping pill and their preparing method and application

A technology of Boling melon seeds and extracts, which is applied in the field of Boling melon seeds extract and its dripping pill dosage forms, and the preparation of extracts and dropping pills, which can solve the problems of small prescriptions, affecting drug absorption, and backward Tibetan medicine preparation technology, etc.

Inactive Publication Date: 2008-05-28
钱毓洲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the small amount of prescriptions and the backward technology of Tibetan medicine preparations, it greatly affects the absorption of medicines

Method used

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  • Pedunculate herpetospermum seed extract, its dripping pill and their preparing method and application
  • Pedunculate herpetospermum seed extract, its dripping pill and their preparing method and application
  • Pedunculate herpetospermum seed extract, its dripping pill and their preparing method and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0113] The preparation of embodiment 1 wave edge melon seed extract that is bulk drug:

Embodiment 1-1

[0115] Boling melon seed extract, its preparation method is as follows:

[0116] 1), pulverize the dried product of wave-lens melon seeds into coarse powder;

[0117] 2), decoct and extract the coarse powder with 80% ethanol of 6 times the amount of coarse powder, extract twice, each time for 2 hours, and combine the decoction;

[0118] 3), the decoction is filtered by the plate and frame suction filtration method, and the filtrate is concentrated under reduced pressure at 40°C until each 1ml of the liquid medicine is equal to 2g of the raw material drug; the pH value of the concentrated solution is adjusted to pH=10 with NaOH, and after the precipitation is dissolved, Use HCl to adjust the pH value to pH=2, centrifuge, and discard the supernatant; wash the precipitate with petroleum ether with a boiling range of 60°C, dry it under low temperature and reduced pressure at 40°C, crush the dry matter into fine powder, and pass through 100 mesh Sieve to obtain the pollen melon se...

Embodiment 1-2

[0120] The preparation method of Boling melon seeds extract, its steps and raw materials are as embodiment 1-1, in step 2) decoct and extract the coarse powder with 80% ethanol of 8 times the amount of coarse powder; in step 3) make the filtrate Concentrate under reduced pressure at 50°C; use NaOH to adjust the pH value of the concentrated solution to pH=10.5, after the precipitate is dissolved, adjust the pH value to pH=2.5 with HCl, centrifuge, discard the supernatant; use petroleum ether with a boiling range of 70°C Wash the precipitate, dry it under low temperature and reduced pressure at 50°C, pulverize the dry matter into fine powder, and pass through a 100-mesh sieve to obtain the extract of the melon seeds.

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Abstract

The present invention belongs to the field of Chinese medicine preparation technology, and is especially pedunculate herpetospermum seed extract and its dripping pill and their preparation process and applying technology. By means of pharmacodynamic research, the effective part, total pedunculate herpetospermum lignan, and the effective dosage are determined. Through modern technological process, total pedunculate herpetospermum lignan is extracted and further prepared into the total pedunculate herpetospermum lignan dripping pill used for treating viral hepatitis and tumor.

Description

technical field [0001] The invention belongs to the technical field of inventions of traditional Chinese medicine preparations, in particular to the technical field of the extract of Boling melon seeds and its dripping pill formulation, the preparation method and application of the extract and the dropping pill. Background technique [0002] my country is a high-incidence area of ​​viral hepatitis, among which chronic hepatitis B has attracted special attention because of its gradual development, difficulty in control, poor prognosis and complicated pathogenesis. At present, nearly 130 million people in the country are carriers of hepatitis B virus, 50 million people suffer from chronic hepatitis, and about 230,000 people die of hepatitis every year (a survey statistics from the Ministry of Health in December 2002 showed that: hepatitis It is still the infectious disease with the highest morbidity and mortality in my country), plus other known and unknown viral hepatitis dise...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/42A61P1/16A61P31/14A61P31/20A61K131/00
Inventor 袁海龙
Owner 钱毓洲
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