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Medication composition of plant estrogens for treating colpitis

A technology of phytoestrogen and composition, which is applied in the field of herbal medicine composition for vaginitis, and can solve the problems of increasing the risk of breast cancer and endometrial cancer, uterine bleeding, etc.

Inactive Publication Date: 2008-09-17
MEDICAL COLLEGE OF CHINESE PEOPLES ARMED POLICE FORCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, local treatment is mainly based on western medicine, and diethylstilbestrol is commonly used for vaginal topical treatment, but this kind of medicine is easy to cause uterine bleeding, and at the same time, it can also increase the risk of breast cancer and endometrial cancer for users

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Extraction method of Pueraria total flavonoids:

[0023] Take pueraria root powder, add water to decoct twice, each time add 10 times of raw material water, cook for 3 hours each time, combine the decoction liquid, let it pass through the macroporous resin, wash with water, 10%, 30%, 50% ethanol in turn Take off, collect and dry total flavonoids.

Embodiment 2

[0025] Extraction method of total flavonoids of Epimedium:

[0026] Take the coarse powder of Epimedium, add water to decoct twice, each time add 10 times the raw material water, boil for 3 hours each time, combine the decoction liquid, let it pass through the macroporous resin, water in turn, 10%, 30%, 50% Eluted with ethanol, collected and dried total flavonoids of Epimedium.

Embodiment 3

[0028] Extraction method of total coumarin from Fructus Cnidii:

[0029] Take the coarse powder of Fructus Cnidii, add 95% ethanol to reflux and extract twice, each time add 95% ethanol 10 times as much as the raw material, extract for 3 hours each time, recover ethanol, and refine the total coumarin of Fructus Cnidii.

[0030] The components and weight of Embodiment 4 to Embodiment 23 are expressed in Table 1.

[0031] Table 1:

[0032] Example 4

[0033] Example 11

[0034] Example 21

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PUM

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Abstract

A composite vegetative estrin medicine in the form of suppository, gel or film for treating vagititis and improving the toughness of vagina and its resistance to bacteria is proportionally prepared from vegetative estrin, cnidiadin, borneol, and at least one of matrine, phellodendrine, berberine, etc and their physiocologically acceptable salts.

Description

technical field [0001] The invention relates to a herbal medicine composition, in particular to a herbal medicine composition for vaginitis. Background technique [0002] At present, the medicine for the treatment of women's vaginitis is mainly based on Western medicine, mostly suppositories and ointments that produce local effects. Such as chlorhexidine acetate suppository, Shuangzotai suppository and ointment, among them, chlorhexidine acetate suppository is mainly used for sterilization and anti-inflammation, which is suitable for bacterial vaginosis, but it has no obvious effect on gynecological mixed infection and is more irritating. Shuangzotai suppository and ointment are effective for various vaginitis, but less effective for bacterial vaginosis. [0003] Mycotic vaginitis is one of the common gynecological diseases. About 80% to 90% of mycotic vaginitis is caused by Candida albicans infection; 10% to 20% are other Candida and Torulopsis infections. Candida albican...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K45/06A61K31/56A61P15/02
Inventor 陈虹刘岱琳张莉高颖白淑芳张静泽董小青葛新雷志勇
Owner MEDICAL COLLEGE OF CHINESE PEOPLES ARMED POLICE FORCE
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