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Hard medicine capsule

A technology for capsules and medicines, applied in the field of hard medicine capsules and preparation, can solve the problems of gelatin capsules being sensitive to changes in temperature and humidity, hidden dangers of animal protein safety, inconvenient transportation and storage, etc. The effect of easy transportation and storage

Inactive Publication Date: 2010-01-06
刘杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Traditional hollow capsule production raw materials are medicinal gelatin, medicinal gelatin belongs to animal protein, but animal protein has potential safety hazards; in addition, gelatin capsules are sensitive to changes in temperature and humidity, and if the temperature and humidity are not properly controlled, they are easy to break and are not easy to transport and storage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The hard medicine capsule of the present invention is made into the raw material of active ingredient by weight percentage: 35% of hydroxypropyl methylcellulose; 55% of hydroxypropyl starch; 10% of chitin; The concentration of the aqueous solution is 10%; the viscosity of the aqueous solution is 1000 centipoise; the aqueous solution is left to stand or decompressed to completely degassed in the glue tank, and the shaft needle is preheated to 70°C before dipping into the aqueous solution at a heating temperature of 40°C, and placed for 2 Minutes; take out the needle and dry it in a closed drying oven at a temperature of 30°C; form a layer of hard shell-like blend polymer film on the needle, pull out the needle after demoulding, and trim it to obtain Hard drug capsule shell;

[0013] The capsule sleeve adopts a needle with a diameter larger than that of the capsule shell to prepare an aqueous solution through the above-mentioned technological process, soak in the liquid, ...

Embodiment 2

[0017] The hard medicine capsule of the present invention is made into the raw material of active ingredient by weight percentage: 40% of hydroxypropyl methylcellulose; 47% of hydroxypropyl starch; 13% of chitin; The concentration of the aqueous solution is 20%; the viscosity of the aqueous solution is 5000 centipoise; the aqueous solution is left to stand or decompressed to completely degassed in the glue tank, and the shaft needle is preheated to 75°C before dipping into the aqueous solution at a heating temperature of 50°C, and placed for 2 Minutes; take out the needle and dry it in a closed drying oven at a temperature of 35°C; form a layer of hard-shell blend polymer film on the needle, pull out the needle after demoulding, and trim it to obtain Hard drug capsule shell;

[0018] The capsule sleeve adopts a needle with a diameter larger than that of the capsule shell to prepare an aqueous solution through the above-mentioned technological process, soak in the liquid, dry, ...

Embodiment 3

[0022] The hard medicine capsule of the present invention is made into the raw material of active ingredient by weight percentage: 45% of hydroxypropyl methylcellulose; 40% of hydroxypropyl starch; 15% of chitin; The concentration of the aqueous solution is 30%; the viscosity of the aqueous solution is 10,000 centipoise; the aqueous solution is left to stand or decompressed to completely degassed in the glue tank, and the shaft needle is preheated to 80°C before dipping in the liquid, then immersed in the water solution at a heating temperature of 60°C, and placed for 2 Minutes; take out the needle and dry it in a closed drying oven at a temperature of 55°C; form a layer of hard shell-like blend polymer film on the needle, pull out the needle after demoulding, and trim it to obtain Hard drug capsule shell;

[0023] The capsule sleeve adopts a needle with a diameter larger than that of the capsule shell to prepare an aqueous solution through the above-mentioned technological pr...

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PUM

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Abstract

An empty capsule for medicines is proportionally prepared from hydroxypropyl methylcellulose, hydroxypropyl starch and chitin through preparing aqueous solution, immersing die in it, baking, removing die and trimming. It has bactericiding action.

Description

technical field [0001] The invention relates to a hollow capsule, in particular to a hard medicine capsule made of pure plant cellulose as a main raw material and a preparation method thereof. Background technique [0002] Traditional hollow capsule production raw materials are medicinal gelatin, medicinal gelatin belongs to animal protein, but animal protein has potential safety hazards; in addition, gelatin capsules are sensitive to changes in temperature and humidity, and if the temperature and humidity are not properly controlled, they are easy to break and are not easy to transport and storage. At present, starch and konjac glucomannan are used to produce hollow capsules, and there are records of cellulose-based hollow capsules made of plant cellulose as the main raw material. Contents of the invention [0003] The object of the present invention is to provide a hard medicine capsule prepared with pure plant cellulose as the main raw material. [0004] The plant cap...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K47/38A61J3/07
Inventor 刘杰高玉宁
Owner 刘杰