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Curing purpose of total flavonoids from mulberry tree leaf

A technology of total flavonoids and mulberry leaves, applied in medical preparations containing active ingredients, plant raw materials, endocrine system diseases, etc., can solve the problems that have not been seen to improve insulin resistance, and the mechanism of hypoglycemia is not clear, so as to increase insulin sensitivity sex, improve blood sugar, and improve insulin resistance

Inactive Publication Date: 2007-09-12
陈秋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Recent studies have found that the total flavonoids of mulberry leaves can reduce the blood sugar level of alloxan diabetic rats, but the mechanism of lowering blood sugar is still unclear
In addition, studies have shown that the total flavonoids of mulberry leaves and their components such as rutin, quercetin, isoquercetin, and dihydrocamellia also have anti-oxidation, lowering plasma cholesterol, lowering blood pressure, anti-inflammatory, antispasmodic, anti-ulcer, and anti-inflammatory properties. Protein non-enzymatic glycosylation and other effects, but there is no report that it improves insulin resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0056] Mode 1: prepare mulberry leaf total flavonoids granules according to the technical method known to those skilled in the art

[0057] Take 200 g of total flavonoids of mulberry leaves, use modified starch microcrystalline cellulose as filler, methyl cellulose as binder, granulate, dry, granulate, divide into 350 mg / bag, and pack to get the product.

[0058] Mode 2: prepare mulberry leaf total flavonoids capsules according to the technical method known to those skilled in the art

[0059] Take 200 g of total flavonoids of mulberry leaves, use modified starch microcrystalline cellulose as filler, methyl cellulose as binder, granulate, dry, granulate, subpackage into 350 mg / capsule, and pack.

[0060] Mode 3: prepare mulberry leaf total flavonoids tablet according to the technical method known to those skilled in the art

[0061] Take 200 g of total flavonoids of mulberry leaves, use modified starch microcrystalline cellulose as filler, methyl cellulose as binder, granulat...

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Abstract

The present invention is medicinal use of mulberry leaf flavonid, and features that mulberry leaf flavonid is used in medicine for treating insulin resistance disease. Intracorporeal and extracorporeal experiments show that mulberry leaf flavonid has excellent effect of treating insulin resistance disease, and possesses obvious effect of improving insulin resistance, improving blood sugar raising caused by insulin resistance and raising the insulin sensitivity of type II diabetics, low toxicity, less side effect and high use safety.

Description

Technical field [0001] The invention relates to the use of total flavonoids of mulberry leaves. Background technique [0002] Insulin resistance (IR) is a pathophysiological state of sub-cells, cells, tissues or the body. The classic definition refers to the need for more than normal insulin to produce normal physiological effects in insulin effector organs. Modern insulin The concept of resistance generally refers to the reduced effect of insulin on the uptake and clearance of glucose in peripheral tissues. The main target organs of insulin are the liver, skeletal muscle and adipose tissue. The main physiological effects include the uptake and processing of glucose mediated by it (oxidation and storage of sugar), the promotion of protein and fat synthesis, the inhibition of gluconeogenesis, the inhibition of lipolysis and Ketone body production, etc. Insulin resistance is an important etiology and distinctive feature of type 2 diabetes. It also plays an important role in...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61P5/50A61K127/00
Inventor 陈秋
Owner 陈秋
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