Traditional Chinese medicine preparation for animals and preparation method thereof

A technology of traditional Chinese medicine preparations and intestinal diseases, which is applied in the direction of medical formulas, medical preparations containing active ingredients, antibacterial drugs, etc., and can solve problems such as restricting the development of the pig industry, harming human health, and drug resistance

Inactive Publication Date: 2011-01-12
HENAN AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the process of pig production, the incidence of yellow and pullorum in piglets is sometimes as high as about 50%, and the fatality rate is about 20%. It is greatly suppressed, and most of them become dead pigs, which seriously restricts the development of the pig industry.
[0003] At present, the drugs used to treat such diseases at home and abroad basically use synthetic drugs such as furazolidone, oxytetracycline, norfloxacin, and ciprofloxacin. Serious drug resistance will occur. The prevalence of E. coli drug-resistant strains has caused many antibacterial agents that were originally effective in preventing and treating this disease to have no obvious effect in some pig farms, but the application dose has been continuously increased.
And due to the long-term unreasonable abuse of synthetic antibacterial agents, antibiotics, etc., the drug residues in the produced animal products seriously exceed the standard, which not only affects exports, but also damages human health, causing serious losses

Method used

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  • Traditional Chinese medicine preparation for animals and preparation method thereof
  • Traditional Chinese medicine preparation for animals and preparation method thereof
  • Traditional Chinese medicine preparation for animals and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] First weigh poplar leaves with a weight percentage of 50% and Humulus humulus with a weight percentage of 50%, place them in an extraction concentrator, add 6 times the amount of water, and extract dynamically in a vacuum at a low temperature; concentrate to a relative For the clear paste with a density of 1.2, take the clear paste and add ethanol with a concentration of 75% to carry out alcohol precipitation; stand for 24 hours, recover ethanol under reduced pressure, stand for 24 hours, filter, and obtain the extract for later use; put the obtained extract in Add purified water with a total water content of 30% in the concentrated preparation tank, add the extract under stirring, stir evenly, coarsely filter into the thin preparation tank, add purified water, check the pH value to 5, and fine filter to obtain the product.

Embodiment 2

[0019] First weigh poplar leaves with a weight percentage of 60% and Humulus humulus with a weight percentage of 40%, place them in an extraction concentrator, add 7 times the amount of water, and extract dynamically in a vacuum at a low temperature; concentrate to a relative For the clear paste with a density of 1.2, take the clear paste and add ethanol with a concentration of 75% to carry out alcohol precipitation; stand still for 36 hours, recover ethanol under reduced pressure, stand for 36 hours, filter, and obtain the extract for later use; put the obtained extract in Add purified water with a total water content of 30% in the concentrated preparation tank, add the extract under stirring, stir evenly, coarsely filter into the thin preparation tank, add purified water, check the pH value to 6, and fine filter to obtain the product.

Embodiment 3

[0021] First weigh poplar leaves with a weight percentage of 70% and Humulus humulus with a weight percentage of 30%, place them in an extraction concentrator, add 8 times the amount of water, and extract dynamically in a vacuum at a low temperature; concentrate to a relative For the clear ointment with a density of 1.25, take the ointment and add ethanol with a concentration of 85% for alcohol precipitation; let stand for 48 hours, recover ethanol under reduced pressure, let stand for 48 hours, filter, and obtain the extract for later use; put the obtained extract in Add purified water with a total water content of 30% in the concentrated preparation tank, add the extract under stirring, stir evenly, coarsely filter into the thin preparation tank, add purified water, check the pH value to 7, and fine filter to obtain the product.

[0022] Stability test

[0023] 1. API:

[0024] Humulus, poplar leaves

[0025] 2. Preparation stability test

[0026] The stability of prepara...

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PUM

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Abstract

The invention relates to a Chinese medicinal preparation for livestock and its preparation. The preparation comprises the following components in weight percentage: poplar leaf 40-70%, and Japanese hop 30-60 %.The preparation method comprises the following steps: weighing 40-70wt% of poplar leaf and 30-60 wt% of Japanese hop, placing in an extraction thickener, adding 6-8 times of water, vaccum extracting in dynamic state at low temperature, concentrating to relative density of 1.2-1.25, adding 75-95% ethanol for alcohol precipitation, standing for 24-48 h, recovering ethanol under reduced pressue, standing for 24-48 h, filtering, adding purified water 30% of total amount into a tank, adding extract into the water under stirring, stirring, coase filtering, adding purified water, detectingpH between 5-7, and refining to obtain the final product. The preparation has unique therapeutic effect, no toxic or adverse side effect, no residue and nuisance, no influence to animal production performance, any drugfastness generation, easily-accessible raw materials, low cost, and administration cost lower than that of chemical pharmaceutical preparation.

Description

technical field [0001] The invention relates to a veterinary traditional Chinese medicine preparation, and also relates to a preparation method of the veterinary traditional Chinese medicine preparation. Background technique [0002] Colibacillosis is the most serious bacterial intestinal infectious disease in piglet feeding period. Its pathogenesis is that Escherichia coli colonizes the epithelium of the small intestinal mucosa of piglets by the adhesin on its surface, produces enterotoxin, activates adenylate cyclase and guanylate cyclase, causes ion balance imbalance, and causes severe diarrhea. Lead to dehydration and acid-base balance disorders. In the process of pig production, the incidence of yellow and pullorum in piglets is sometimes as high as about 50%, and the fatality rate is about 20%. Suppressed greatly, most become stiff pigs, seriously restricting the development of the pig industry. [0003] At present, the drugs used to treat such diseases at home and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/60A61P31/04A61P1/00
Inventor 张素梅杜向党刘建华莫娟刘兴金张晓会
Owner HENAN AGRICULTURAL UNIVERSITY
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