Medicine composition containing insulin intensifier and miglitol
A technology of insulin sensitizer and composition, which is applied in the direction of drug combination, medical preparations containing active ingredients, active ingredients of heterocyclic compounds, etc., to achieve the effect of improving utilization, lowering blood sugar level, and reducing intake
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Embodiment 1
[0026] prescription
[0027] Rosiglitazone 1.5g
[0028] Miglitol 20g
[0029] Microcrystalline Cellulose 100g
[0030] 8% hydroxypropyl methylcellulose solution appropriate amount
[0031] Low-substituted hydroxypropyl cellulose 50g
[0032] Magnesium Stearate 2g
[0033] Preparation process: rosiglitazone and miglitol were passed through a 100-mesh sieve, microcrystalline cellulose and low-substituted hydroxypropyl cellulose were passed through a 80-mesh sieve, and the prescription amount of rosiglitazone, miglitol and low-substituted hydroxypropyl cellulose was weighed. Mix hydroxypropyl cellulose and microcrystalline cellulose evenly, add an appropriate amount of 8% hydroxypropyl methylcellulose solution to granulate, dry at 60°C, granulate with a 16-mesh sieve, add prescription amount of magnesium stearate to the dry granules and mix Mix evenly and press into tablets.
Embodiment 2
[0035] Pioglitazone 10g
[0036] Miglitol 20g
[0037] Microcrystalline Cellulose 100g
[0038] PEG6% solution appropriate amount
[0039] Carboxymethyl Cellulose Calcium 15g
[0040] Magnesium Stearate 2g
[0041] Preparation process: with embodiment 1.
Embodiment 3
[0043] Pioglitazone 10g
[0044] Miglitol 20g
[0045] 150g pregelatinized starch
[0046] Sodium carboxymethyl cellulose 1% solution appropriate amount
[0047] Enteric coating powder appropriate amount
[0048] Carboxymethyl Cellulose Calcium 15g
[0049] Magnesium Stearate 2g
[0050] Preparation process: According to the conventional tablet process, it is made into tablets (ball cores) of required specifications, and then coated with enteric coating powder.
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