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Compound prescription for curing osteoarthropathy as well as preparation technique thereof

A technology for osteoarthritis and formula, which can be used in medical preparations containing active ingredients, bone diseases, pharmaceutical formulas, etc., and can solve problems such as difficulty in controlling dosage

Inactive Publication Date: 2010-09-29
BEIJING ZHONGKE YONGHE PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditional Chinese medicine is unique in the treatment of osteoarthritis, but the oral preparations of traditional Chinese medicine often contain highly toxic ingredients such as Aconitum Aconiti, Nanxing, Nuxyche, etc., and the dosage is difficult to control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Glucosamine 70kg Vinegar Corydalis 700kg Wujiapi 200kg Paeoniae Alba 180kg

[0029] Vitamin C10kg Cornstarch 10kg

[0030] Vinegar corydalis is crushed into coarse powder, first heated to reflux with 4 times the amount of 60% ethanol for 3 hours, then heated to reflux with 3 times the amount of 60% ethanol for 2 hours, combined the two extracts, filtered, recovered ethanol, and concentrated the filtrate to a relatively Density is 1.15-1.20 extract (50-60 ℃ heat test), add cornstarch and mix evenly, pass through 120 mesh sieve to preheat, spray dry, and prepare powder for later use. Boil Wujiapi and Baishao three times with 8-10 times the amount of water, followed by 2 hours, 1.5 hours, and 1 hour, filter, and concentrate the filtrate to a relative density of 1.15-1.20 extract (heat test at 50-60°C) , spray-dried. The above two medicinal powders are evenly mixed with vitamin C powder and glucosamine according to the formula ratio. Pack capsules, each containing 0.5g, ...

Embodiment 2

[0032] Glucosamine 100kg Vinegar Corydalis 1200kg Wujiapi 380kg Paeoniae Alba 320kg

[0033] Vitamin C 20kg Corn Starch 20kg

[0034] Vinegar corydalis is crushed into coarse powder, first heated to reflux with 4 times the amount of 60% ethanol for 3 hours, then heated to reflux with 3 times the amount of 60% ethanol for 2 hours, combined the two extracts, filtered, recovered ethanol, and concentrated the filtrate to a relatively Density is 1.15-1.20 extract (50-60 ℃ heat test), add cornstarch and mix evenly, pass through 120 mesh sieve to preheat, spray dry, and prepare powder for later use. Boil Wujiapi and Baishao three times with 8-10 times the amount of water, followed by 2 hours, 1.5 hours, and 1 hour, filter, and concentrate the filtrate to a relative density of 1.15-1.20 extract (heat test at 50-60°C) , spray-dried. The above two medicinal powders are evenly mixed with vitamin C powder and glucosamine according to the formula ratio. Pack capsules, each containing 0....

Embodiment 3

[0036] Glucosamine 90kg Vinegar Corydalis 940kg Wujiapi 315kg Paeoniae Alba 240kg

[0037] Vitamin C15kg Cornstarch 15kg

[0038] Vinegar corydalis is crushed into coarse powder, first heated to reflux with 4 times the amount of 60% ethanol for 3 hours, then heated to reflux with 3 times the amount of 60% ethanol for 2 hours, combined the two extracts, filtered, recovered ethanol, and concentrated the filtrate to a relatively Density is 1.15-1.20 extract (50-60 ℃ heat test), add cornstarch and mix evenly, pass through 120 mesh sieve to preheat, spray dry, and prepare powder for later use. Boil Wujiapi and Baishao three times with 8-10 times the amount of water, followed by 2 hours, 1.5 hours, and 1 hour, filter, and concentrate the filtrate to a relative density of 1.15-1.20 extract (heat test at 50-60°C) , spray-dried. The above two medicinal powders are evenly mixed with vitamin C powder and glucosamine according to the formula ratio. Pack capsules, each containing 0.5g, ...

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PUM

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Abstract

The invention discloses a compound formula for osteoarthropathy, which is mainly made of dextrosamine, extract of vinegar rhizoma corydalis, extract of cortex periplocae, extract of white paeony root and vitamin C and certain supplementary materials. The preparation technologies of Chinese traditional medicine extract include that the vinegar rhizoma corydalis is milled to crude powders; the crude powders are heated and reflowed twice through ethanol, and the extracted liquid are combined twice; the ethanol is recycled after being filtered; the filtered liquid is concentrated to an extract with relative density of 1.15 to 1.20; and finally the extract is sprayed and dried. The cortex periplocae and the white paeony root are boiled with water for three times and then filtered; and then thefiltered liquid is concentrated to an extract with relative density of 1.15 to 1.20; and finally the extract is sprayed and dried. The compound formula has the advantages of being used for curing pantomime and joint pain and inconvenient moving, etc., due to arthritis, retrogradearthritis, rheumatoid arthritis and rheumatoid arthritis, and being used for preventing and curing and improving various symptom due to osteoporosis.

Description

technical field [0001] The invention relates to a composite formula for osteoarthritis, belonging to the technical field of medicines for treating osteoarthrosis. Background technique [0002] Osteoarthrosis is a chronic joint disease characterized by local articular cartilage degeneration, bone loss, joint edge spur formation, joint deformity and subchondral bone density, also known as osteoarthritis, degenerative osteoarthritis, hyperplasia arthritis, senile arthritis. It occurs more frequently in people over 50 years old, and women are more common than men. The disease affects the quality of life of middle-aged and elderly patients to varying degrees. Learned from the "Asia-Pacific International Arthritis Symposium" concluded in Korea. In Asia, about 1 in 3 people suffer from osteoarthritis, and in most developed countries, it is more common than heart disease, cancer, and diabetes. [0003] The use of non-steroidal anti-inflammatory painkillers is a traditional treatm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K36/66A61K36/254A61K31/16A61P19/08A61K31/375A61K31/7008
Inventor 鄢良张韬程华
Owner BEIJING ZHONGKE YONGHE PHARMA TECH