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Assay device

A technology for testing rooms and testing equipment, which is applied in the field of cantilever detectors, and can solve problems such as limited sensitivity that has not caused widespread application of the technology

Inactive Publication Date: 2008-06-11
ROYAL MELBOURNE INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] It is also known that microcantilevers have been used as a device for detecting the results of chemical reactions, but studies on the limited sensitivity of the beams have not led to any widespread application of the technique

Method used

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Embodiment Construction

[0036] In FIG. 1 an assay device 1 is shown comprising a rotatable platform 2 in the form of a compact disc (CD) with a microfluidic system 3 comprising channels through respective grooves 8, 9, 10 Interconnected inlet 4, secondary chamber 5, test chamber 6 and waste chamber 7. A filter 11 is provided in the channel 8 adjacent to the inlet 4 for filtering substances such as cellular matter from the test fluid introduced into the inlet 4 . The filter 11 preferably consists of porous silicon 12 . A micromechanical valve 13 is also provided in the groove 10 to separate the test chamber 6 and the waste chamber 7 . Said valve 13 moves from a closed position indicated by dashed line 14 to an open position indicated by arrow 15 when the angular velocity of device 1 is greater than a predetermined threshold.

[0037] In operation, a fluid is introduced into the inlet 4 and the device 1 is rotated at the required speed to generate centrifugal suction so that the fluid is pushed throu...

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PUM

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Abstract

An assay device (1) having a rotatable platform (2) with a test chamber (6) and a sensor (20) which undergoes displacement when subject to a particular substance such as a chemical, biological species or other organism. The sensor is a cantilever beam (21) with a porous section (23) to enhance sensitivity.

Description

technical field [0001] The invention relates to an assay device and a cantilever detector. Background technique [0002] The use of compact discs (CDs) for chemical testing is known. The CD has microfluidic structures that define distinct fluid input ports that communicate with associated grooves and fluid mixing chambers. For testing, fluid is placed in the input port and the CD is rotated so that the fluid is pushed by centrifugal suction through the associated channel to the mixing chamber. Clearly, improved CD optics and addressing techniques can be applied to capture images of a particular mixing chamber to determine the results of inspection of any chemical reactions within said mixing chamber. [0003] It is also known that microcantilevers have been used as a device for detecting the results of chemical reactions, but studies on the limited sensitivity of the beams have not led to any widespread application of the technique. Contents of the invention [0004] Ac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48G01N33/53G01N33/50
CPCG01N35/00069G01N33/54373G01N35/00G01N33/50G01N33/53G01N33/48
Inventor J·查菲M·斯特普尔顿
Owner ROYAL MELBOURNE INST OF TECH