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Medicament for treating high blood pressure

A technology of high blood pressure and drugs, applied in the field of drugs for the treatment of high blood pressure, can solve the problems of long treatment cycle, toxic and side effects, etc., and achieve the effect of improving high blood pressure, reducing high blood pressure, and being easy to carry

Inactive Publication Date: 2008-06-18
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, oral preparations are mostly used in the treatment of hypertension, and external preparations have not been seen yet. Oral administration has a long treatment cycle and relatively large toxic and side effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: the medicine for the treatment of hypertension (trade name: ointment for treating hypertension)

[0021] prescription:

[0022] Hanfangji 150g Raw Astragalus 150g Rehmannia glutinosa 120g Huaishan medicine 120g Cornus 100g

[0023] Alisma 120g, Baishao 150g, Fuling 150g, Danpi 120g, Salvia miltiorrhiza 150g, Euonymus 150g, preparation

[0024] method:

[0025] A. Extraction process

[0026] (a) Put 30 meshes of coarse powder of Fangji, raw astragalus, rehmannia glutinosa, Chinese yam, cornus, Alisma, white peony root, Fuling, paeonol, salvia miltiorrhiza, euonymus into a percolation tank with an ultrasonic device Stir with the same amount of solvent 90% ethanol as the medicinal material, cover it to make it wet and swell for 1-4 hours, the dynamic ultrasonic device controls the percolation flow rate to 1-3ml / min, add solvent at any time until the percolation liquid is colorless and odorless Dry until the temperature limit is below 60°C to form a thick ...

Embodiment 2

[0031] Embodiment 2: the medicine for the treatment of hypertension (trade name: Catapula for the treatment of hypertension)

[0032] prescription:

[0033] Hanfangji 150g Raw Astragalus 150g Rehmannia glutinosa 120g Huaishan medicine 120g Cornus 100g

[0034] Alisma 120g, Baishao 150g, Fuling 150g, Danpi 120g, Salvia miltiorrhiza 150g, Euonymus 150g

[0035] Preparation:

[0036] A. Extraction process:

[0037] (a) Put 30 meshes of coarse powder of Fangji, raw astragalus, rehmannia glutinosa, Chinese yam, cornus, Alisma, white peony root, Fuling, paeonol, salvia miltiorrhiza, euonymus into a percolation tank with an ultrasonic device Stir with the same amount of solvent 90% ethanol as the medicinal material, cover it to make it wet and swell for 1-4 hours, the dynamic ultrasonic device controls the percolation flow rate to 1-3ml / min, add solvent at any time until the percolation liquid is colorless and odorless Dry until the temperature limit is below 60°C to form a thick...

Embodiment 3

[0042] Embodiment 3: the medicine ointment stability investigation for the treatment of hypertension

[0043] According to the "Technical Requirements for New Drug Research of Traditional Chinese Medicine" promulgated and implemented by the State Drug Administration, the technical requirements for quality stability research of new traditional Chinese medicines are stipulated. The ointment and cataplasm for treating angina pectoris were made according to the established process, and the properties, moisture retention, content and microbiological inspection items were observed at room temperature. The results show that all the control indicators meet the national ointment quality standards, and the quality is stable after being placed at room temperature for six months.

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Abstract

The invention discloses a medicine which is prepared by the Chinese herbs with the functions of clearing away the heart fire and eliminating phlegm, sedation and decompression and is used for treating high blood pressure. The medicine is a refined external-use compound paste prepared by the effective ingredients of Radix Stephaniae Tetrandrae, Radix Astragali, Radix Rehmanniae Preparata, Rhizoma Diosscoreae, Fructus Corni, Rhizoma Alismatis, Radix Paeoniae Alba, Poria, Cortex Moutan, Radix Salviae Miltiorrhizae and Euonymus alatus. The invention has evident effect on decompression, sedation and diuresis. The paste body of the plaster is fine, soft and smooth, easy to be coated on cloth and uneasy to melt, easy for carrying and use because of small size, and good for quick recovery of focus. The poultice has stable drug property and has the characteristics of quick percutaneous absorption, good ventilation property and gradual drug releasing. Compared with the oral preparation, the invention has the advantages of no liver-intestines first-filter action, no influence from gastrointestinal degradation and high bioavailability. Compared with injection, the invention has the advantages of convenient use and no pain. Compared with ointment, the invention has the advantages of accurate dose and fixed absorption area. Compared with black plaster and sticking plaster, the invention has the advantages of no sensibility on skin, no pollution to clothes, long effect, percutaneous absorption and convenient carrying and use.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to medicines for treating hypertension prepared by taking Chinese herbal medicines for clearing away heart-fire, resolving phlegm, calming and lowering blood pressure as raw materials. technical background [0002] Hypertension is a common and frequently-occurring disease that seriously endangers human health. There are many kinds of drugs for treating hypertension such as application number 01100306.5 on January 2, 2001, and publication number CN1362152A on August 7, 2002. "Medicine and its preparation method" mainly has the effects of lowering blood pressure, sedation, and diuresis, and is mainly used to treat diseases such as exuberant liver fire, dizziness, irritability, phlegm-fire congestion, and high blood pressure. [0003] In recent years, the research work of applying traditional Chinese medicine to treat hyperlipidemia has developed greatly. There ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/06A61P9/12
Inventor 李建民高惠明
Owner TIANJIN ZHONGBAO PHARMACY
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