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'Yinhuanghanhua' dropping pill for treating upper respiratory tract infection

A technology for upper respiratory tract and drop pills, which is applied to respiratory diseases, devices that make drugs into special physical or ingestible forms, and pill delivery, etc. It can solve the problems of inconvenient taking and carrying, low dissolution rate, and uneven quality and other issues to achieve the effect of improving bioavailability, accelerating dissolution and absorption, and improving stability

Inactive Publication Date: 2008-07-02
SHANGHAI ZHONGXI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These dosage forms are inconvenient to use, painful, inconvenient to take and carry, or expensive. Among them, the active ingredients in Yinhuang Hanhua Tablets are easy to decompose and deteriorate, and the content of active ingredients is not controlled, resulting in uneven quality and difficult to guarantee the effect.
[0003] In addition, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the drug efficacy. The play also directly affects the therapeutic effect

Method used

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  • 'Yinhuanghanhua' dropping pill for treating upper respiratory tract infection
  • 'Yinhuanghanhua' dropping pill for treating upper respiratory tract infection
  • 'Yinhuanghanhua' dropping pill for treating upper respiratory tract infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Example 1 Take 36g each of honeysuckle extract and scutellaria baicalensis extract, add 14.4g polyethylene glycol 6000, 57.6g polyoxyl 40 stearate, 1.44g citric acid, 2.88g menthol and 2.88g aspartame Sweet. After mixing and crushing, put the mixed powder in a heating container and heat it to 60~90℃ while stirring to melt into a uniform liquid medicine. Drop the medicine liquid into simethicone at 0~40℃, and wait for it to solidify. Collect and remove the surface condensing agent, dry it and get it.

Embodiment 2

[0066] Example 2 Take 36 g each of honeysuckle extract and scutellaria baicalensis extract, add 28.8 g polyethylene glycol 6000, 115.2 g polyoxyl 40 stearate, 2.16 g citric acid, 4.32 g menthol and 4.32 g aspartame Sweet. After mixing and crushing, put the mixed powder in a heating container and heat it to 60~90℃ while stirring to melt into a uniform liquid medicine. Drop the medicine liquid into simethicone at 0~40℃, and wait for it to solidify. Collect and remove the surface condensing agent, dry it and get it.

Embodiment 3

[0067] Example 3 Take 36g each of honeysuckle extract and scutellaria baicalensis extract, add 108g polyethylene glycol 6000, 108g polyethylene glycol 4000, 2.88g citric acid, 5.76g menthol and 5.76g aspartame, mix and crush them , Put the mixed powder in a heating container, heat to 60~90℃ while stirring, melt into a uniform liquid medicine, drop the medicine liquid into simethicone at 0~40℃, collect and remove the surface condensation after solidification Agent, get dry.

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Abstract

The invention discloses a medicine combination of YinHuang buccal drop pills used for treating upper respiratory tract infection and has the functions of clearing away heat and toxic material, diminishing inflammation and antimicrobial; the invention consists of honeysuckle extract, radix scutellariae extract, matrix, stabilizing agent and corrective. The invention provides a preparation method.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a Yinhuang containing chemical dripping pill preparation and a preparation method thereof. Background technique [0002] Chinese medicine honeysuckle and scutellaria are commonly used to clear away heat, detoxify, and reduce inflammation. The prepared preparations are used to treat upper respiratory tract infection, acute tonsillitis and fever, cough, and sore throat caused by wind-heat invading the lungs. At present, there are many dosage forms on the market, such as injections, tablets, granules, oral liquids, lozenges, and capsules prepared from honeysuckle extract and scutellaria extract. These dosage forms are either inconvenient to use, painful, or inconvenient to take and carry, or are expensive. Among them, the active ingredients in Yinhuang Hanhua Tablets are easy to decompose and deteriorate, and the content of active ingredients is not controlled, resu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K9/20A61K47/02A61K47/12A61K47/32A61K47/34A61K47/36A61P11/00A61P11/04A61J3/06A61K47/10
Inventor 邢琦谭波
Owner SHANGHAI ZHONGXI PHARMA
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