Biomarkers for breast cancer

A biomarker, technology for breast cancer, applied in the field of clinical diagnostics
CN101223445AInactive Publication Date: 2008-07-16THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
18 Cites 3 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Publication Date
2008-07-16
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying breast cancer status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as breast cancer or non-breast cancer. The biomarkers can be detected by SELDI mass spectrometry.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] Related applications

[0002] This application claims priority to US Provisional Application 60 / 685,459, filed May 26, 2005, which is hereby expressly incorporated by reference in its entirety. 【Technical field】

[0003] In general, the present invention pertains to clinical diagnostics. 【Background technique】

[0004] Breast cancer is the most commonly diagnosed cancer in women. Presymptomatic screening to detect early-stage breast cancer while it is still resectable and has a chance of cure can greatly reduce breast cancer-related mortality. Unfortunately, only 63% of breast cancers (1992-1999, USA) are detected at diagnosis (Jemal, A. et al. (2004) CA Cancer J. Clin. 54:8-29). Small lesions are often missed or not seen even with mammography, especially in young women and women with dense breast tissue (Antman, K. and Shea, S. (1999) JAMA 281: 1470-1472). The potential to identify molecular markers of these small lesions that are invisible to imaging techniques w...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More