Fast high-precision detecting method for animal medicine residue in food

Abstract

The invention provides a fast high-accuracy method for detecting agricultural and veterinary products residues in food, including following four steps: (1) matrix pre-treatment; (2) adding analysis protecting agent; (3) introducing sample and detecting on machine; (4) data processing. The detecting method, under the condition that GC / MS instrument detecting sensitivity is no changed, and with large volume injection, could reduce pre-treatment sample amount sharply. At the same time the invention has the advantages of low analysis cost, short analysis time, and uses the standard solution containing analysis protecting agent as standard working solution to draw standard curve for quantifying agricultural and veterinary products residues in various kinds of vegetable, fruit and corn substrates, and quantifies agricultural and veterinary products residues in various kinds of substrates with one standard curve, and has good applicability, the sensibility, accuracy and precision are all in accordance with command of agricultural and veterinary products multi-residues technology, and is suitable for detecting various kinds of agricultural and veterinary products' residues in food quickly and sensitively.

Description

technical field [0001] The invention relates to a fast and high-precision detection method for agricultural and veterinary drug residues in food. Background technique [0002] At present, with the wide application of agricultural and veterinary drugs, while increasing the output of agricultural products, the impact of their residues on human health has also attracted more and more attention. In the "Positive List System of Agrochemical Residues in Food" implemented in Japan in June, the residue limit value of most agricultural and veterinary drugs is 10 μg / kg. At present, GC-MS (gas chromatography-mass spectrometry) technology is the most commonly used method at home and abroad to analyze the residues of pesticides and veterinary drugs, but most of these methods have insufficient detection sensitivity, or the pretreatment steps are cumbersome and time-consuming: such as the national standard method, the Japanese notification method, etc. For example, the method of pretreatm...

AI Technical Summary

Problems solved by technology

At present, GC-MS (gas chromatography-mass spectrometry) technology is the most commonly used method at home and abroad to analyze the residues of pesticides and veterinary drugs, but most of these methods have insufficient detection sensitivity, or the pretreatment steps are cumbersome and time-consuming: such as the national standard method, the Japanese notification method, etc. For example, the method of pretreatment including multi-step liquid-liquid distribution and decompression concentration process takes about 5-6 hours to complete the whole pretreatment process; or the analysis cost is high, which cannot meet the requirements of rapid and accurate determination of various foods: if known The post-data processing method of using the matrix-matched standard solution as the standard working solution to draw the standard curve. Every time a matrix is ​​analyzed, the standard curve of the matrix must be prepared again. For those who need to complete the detection tasks of pesticide residues in a large number of different matrices It is said that the workload is huge, the requirements for experimental skills are high, and the data processing is cumbersome, which cannot meet the rapid and multi-residue analysis and detection requirements of front-line experimenters (such as import and export commodity inspection departments).

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