Method for extracting protodioscin from semen trigonellae

Abstract

The invention provides a process for abstracting protodioscin from fenugreek, comprising: (1) pretreatment of the medicinal materials; (2) ultrasonic extraction; (3) process of extract; (4) purification: purifying and separating the extract by the process of macroporous adsorption resin and silica gel column chromatography. The technical features of the invention comprise: firstly, applying the macroporous adsorption resin technology to the preparation of the abstraction and purification of protodioscin, preparing high-purity protodioscin with a conventional method. The method has a simple process, the production cost is low, and product purity is high.

Description

technical field

[0001] The invention relates to the extraction of effective plant components, in particular to a method for extracting protodioscin from fenugreek. Background technique

[0002] Protodioscin (protodioscin) belongs to steroidal saponins (steroidal saponins), is a class of saponins combined with C-27 steroidal compounds and sugar chains, also known as furansterol saponins, and is colorless needle crystals (water) at room temperature. mp is 190~196°C (decomposition), molecular formula is C 51 h 84 o 22 , the molecular weight is 1049.21, and its structure is as follows:

[0003]

[0004] Protodioscin has strong biological activity, such as enhancing male sexual function, poisoning and killing various cancer cells, lowering blood fat, and anti-leukemia. The biological activity of this substance has attracted extensive attention of Chinese and foreign scholars, and many scholars have carried out fruitful work on the biological activity, pharmacological effec...

Images