222results about How to "Easy to scale up industrially" patented technology

The invention relates to a method, a device and a system for separating microalgae, in particular to a method for separating the microalgae from microalgae suspension. The method comprises the following steps of: a) providing algae-containing suspension; b) adding a surfactant or solution of the surfactant into the suspension to dissolve or disperse the surfactant; c) filling bubbles from the bottom of the suspension in which the surfactant is dissolved to ensure that the bubbles are contacted with the microalgae in the rising process; d) ensuring that the microalgae are adsorbed on the bubbles to form aggregate which comprises the bubbles and the algae; e) floating the aggregate to the surface of the suspension to form a foam layer; and f) collecting the foam layer formed by the aggregate. The method, the device and the system have low equipment requirements, are economic and are favorable for scale-up production and industrial application.

The invention relates to an immersed vacuum membrane distillation plant and a sewage treatment technology using the same. The immersed vacuum membrane distillation plant comprises a raw water storage tank, a gas dissolving pump, a raw water heating water tank, a membrane distillation hydrophobic membrane module, a condenser, a vacuum buffer tank, a vacuum pump, a water producing tank, a valve, a measuring instrument, and an automatic controller. The sewage treatment technology is characterized in that: raw water is subject to pH regulation, microfiltration and other pretreatment, then the pretreated raw water enters into the raw water storage tank, the sewage in the raw water storage tank is subject to gas-water mixing through the gas dissolving pump, and then the gas-water mixture enters into the raw water storage tank for heating to a specific temperature, membrane distillation is carried out at the specific temperature, the produced water after membrane distillation is directly reused, and a little thick water is treated concentrately. According to the invention, the use of the plant in sewage treatment reduces the effect of concentration polarization and temperature difference polarization in the sewage, reduces membrane pollution, increases the membrane distillation flux, prolongs the operation period of the membrane module, reduces the heat loss of the pipeline, and increases the heat utilization rate.

The invention provides a novel process for fermenting coenzyme Q10 based on online oxygen consumption rate control. Oxygen consumption rate is controlled at 30-150mmol/L*h during fermentation of coenzyme Q10 strain production, so that growth of thallus and starting and accumulation of coenzyme Q10 synthesis are promoted. Yield of coenzyme Q10 is evidently increased, unit energy consumption is lowered, and production cost is lowered greatly. The novel process is simple to control, high in operability, energy-saving and the like.

The invention discloses a method for preparing graphene/silica nanocomposite fiber through coaxial electrostatic spinning and belongs to the technical field of graphene. The graphene (outer layer)/silica (inner layer) nanocomposite fiber is prepared with a coaxial electrostatic spinning technology in the sol-gel principle. The novel nanocomposite fiber is applied to the field of rubber. The enhancement effect of graphene and silica fiber can be exerted, gathering of graphene can be avoided, and the end effect of the silica fiber can be reduced. The composite fiber can effectively enhance rubber, improve the fatigue resistance and reduce heat generation and the like. Besides, the method has the advantages that equipment is simple, the operation is simple, the controllability is good, industrial amplification is facilitated and the like.

The invention relates to a processing technology for recovering and utilizing the mother solution of glyphosate as a resource, which comprises the following concrete steps: firstly, preprocessing themother solution of glyphosate, and then, separating, concentrating and recovering the glyphosate by a membrane combination technique; returning the concentrated solution to a crystallization working section in the production process of the glyphosate after membrane filtration, thereby effectively recovering and utilizing the glyphosate resource; adsorbing the diluted solution with high efficiency,and further recovering and utilizing the glyphosate; and processing the adsorbed solution by catalytic oxidation with high efficiency to recover the sodium chloride resource with higher purity. The invention achieves the purposes of recovering and utilizing the glyphosate in the mother solution as a resource to the maximum extent and efficiency separating, recovering and utilizing the sodium chloride as a resource, has the advantages of economical technology, high efficiency, good system stability, high safety, easy operation, convenient industrial amplification, and the like, solves the problems of the soil salinization caused by applying water agents with high content of sodium chloride, the processing and disposal of solid wastes of the sodium chloride and the environment pollution, and effectively recovers and utilizes the resources of the glyphosate and the sodium chloride in the mother solution of the glyphosate.

The invention relates to a catalyst and method of the reaction for preparing butanedioic anhydride from maleic anhydride through liquid phase hydrogenation. The problems that in the prior art, the Pd loss rate is high and the maleic anhydride conversion rate and butanedioic anhydride selectivity are low are mainly solved. The catalyst is prepared through a dipping method, carriers or carriers with active auxiliaries are formed into strip-shaped, spherical or special-shaped particles through forming auxiliaries, Pd is the active ingredient, the problems are well solved through the technical scheme of the method for spraying a solution with Pd metal compounds on the forming particle carriers through the dipping method, and the catalyst and the method can be used for the reaction for preparing butanedioic anhydride from maleic anhydride through liquid phase hydrogenation.

The invention discloses a method for preparing hydrogen peroxide. A working liquid and a hydrogen-containing gas are introduced into a slurry bed reactor; a hydrogenated liquid is obtained by reaction in the existence of a catalyst; the hydrogenated liquid reacts with oxygen to obtain the hydrogenated liquid containing hydrogen peroxide in an oxidation reactor; oxidized liquid is extracted and separated from an extraction tower to obtain a hydrogen peroxide solution and working liquid; the slurry bed reactor comprises a cap (12), an expanding section (13) and a draft tube (11); the expanding section (13) is positioned at the lower part of the cap (12); the pipe diameter of the expanding section (13) is greater than that of the cap; the draft tube (11) is arranged in the expanding section (13); the pipe diameter of the draft tube (11) is smaller than that of the cap (12); a bottom opening of the cap (12) extends into the expanding section (13); the outer wall of the cap (12) is connected with the top of the expanding section (13); an upper opening of the draft tube (11) extends into the cap (12); and an opening is formed in the lower part of the draft tube (11). The method disclosed by the invention is stable to operate, and easy for realization of industrial enlargement; no alkali is introduced in the process of preparing hydrogen peroxide; and the risk of explosion caused by hydrogen peroxide decomposition is avoided.

The invention relates to a separation and purification method for a recombinant hepatitis B core antigen. The method includes the steps of thermal denaturation and clarification; ammonium sulfate precipitation; ultrafiltration and concentration, washing filtering and liquid exchange; depolymerization; first-step molecular sieve chromatography; ultrafiltration and concentration, washing filtering and liquid exchange; repolymerization; second-step chromatography. By means of the method, the high-purity, low-host-residue and high-stability recombinant hepatitis B core antigen with a uniform granular structure can be obtained, that is to say, the method has the advantages that the antigen purity is high, the residue of host protein and host nucleic acid is low, antigen particles are uniform, and industrial enlargement is easy.

The invention relates to a high-strength interpenetrating-polymer-network type water-absorbent resin, and a preparation method thereof, belonging to the field of preparation of high polymer materials.The high-strength interpenetrating-polymer-network type water-absorbent resin comprises the following raw materials: 10 to 20 parts of acrylamide monomers, 2 to 10 parts of acrylic acid monomers, 1 to 5 parts of other polymerizable monomers, 0.01 to 0.05 part of a cross-linking agent A, 0.2 to 0.8 part of a cross-linking agent B, 2 to 5 parts of a reactive water-soluble polymer and 0.01 to 0.05 part of an initiator, with the balance being water. The interpenetrating-polymer-network type water-absorbent resin substantially improves the toughness and strength of gel after water absorption on the premise of maintaining water absorption ability; the raw materials are simple and easily available; and a conventional solution polymerization process is employed, which is beneficial for industrialscale-up production of the water-absorbent resin.

The invention relates to the technical field of bioengineering and in particular relates to a synthetic method of L-theanine. The method comprises the following step of synthesizing L-theanine by taking gamma-glutamyl-methylamine synthetase and phosphokinase as catalysts and L-sodium glutamate and ethylamine hydrochloride as substrates. The method can be used for producing a lot of cloned expression proteins as catalysts by taking L-sodium glutamate and ethylamine hydrochloride which are relatively low in price as the initial raw materials, and has the advantages of being mild in reaction condition, strong in specificity, high in reaction conversion rate, simple and convenient to operate, low in requirement on reaction equipment, small in environmental pollution and the like.

The invention discloses a main peptide chain of semaglutide and a preparation method thereof; and more specifically, the invention discloses recombinant protein of intermediate polypeptide of somaluptide. The recombinant protein of the intermediate polypeptide of the somaluptide is leader peptide-DDDDK-GLP-1 (9-37), and has an amino acid sequence as shown in SEQ ID NO. 1. When the intermediate polypeptide of the somalutide is being prepared, the following leader peptides can be adopted: (1) MFLKGDGYVQGIINFEGLHHLVALGLV; (2) KSI; (3) TrxA; (4) DsbA, (5) DsbC; (6) Sumo; (7) GST; (8) Intein; and (9) KPSTYI. The intermediate polypeptide of the somalutide prepared by the preparation method is high in polypeptide purity that the polypeptide purity can be up to 89% or above; and moreover, yield ofthe intermediate polypeptide can be higher than 82%. By adopting ion-exchange separation and purification, the preparation method has the characteristics of being high in degree of separation, good in purification effects, few in impurities and easy to operate.

The invention discloses a method for preparing nano-hydroxyapatite-protein artificial bone imitation materials. The method includes steps of respectively preparing Ca(NO3)2 solution and Na3PO4 solution, dissolving proteins in the Ca(NO3)2 solution, controlling feeding according to a certain calcium-phosphorus molar ratio and carrying out reaction in a rotary packed bed; ageing reacted precipitates at the room temperature; carrying out pumping filtration on the precipitates and washing, drying and grinding the precipitates to obtain nano-hydroxyapatite-protein composite materials; pouring the ground composite materials into cylinder tablet compressing molds and carrying out pressure casting on the composite materials to obtain the cylindrical materials. The method has the advantages that high-gravity technologies and co-precipitation in-situ synthesis processes are combined with one another, so that the nano-hydroxyapatite-protein artificial bone imitation materials with high organic contents can be efficiently prepared; reaction conditions such as the concentration of raw components and the rotational speeds of the rotary packed bed are controlled, so that the artificial bone imitation materials can be prepared; the method is high in efficiency and low in cost, equipment is simple, techniques are safe and stable, the nano-hydroxyapatite-protein artificial bone imitation materials are high in organic content and can be produced under regulation and control, the proteins which are raw material are universal, and a novel way is provided for producing biological materials on a large scale.

A process for preparing perfluorosulfonyl resin includes copolymerization of perfluorosulfonyl vinylether with tetrafluoroethene in the presence of perfluoroalkane/perfluorocycloether mixture and initiator, and adding haloalkane for precipitation or adding deionized water for distilling. Its advantages are high content (more than 20%), and low equivalent weight.

The invention relates to metal doped modified layered [delta]-MnO2, preparation and applications thereof. According to the present invention, the metal doped modified layered [delta]-MnO2 is preparedby adding a settling agent through a hydrothermal method, wherein the specific surface area is increased by 5 times compared with the undoped layered [delta]-MnO2, and the pore channels are dense, such that the metal doped layered [delta]-MnO2 has high catalytic oxidation activity and high chlorine resistance, and has efficient catalytic degradation performance on refractory volatile organic compounds in organic waste gas; and the preparation method is simple, and has industrial application value.

The invention relates to the technical field of ore smelting, and in particular relates to a roasting method which is used for preventing ore powder from caking in the mixed rare earth ore smelting process and is easy to industrially amplify. According to the method, a material can be prevented from caking through adding a grinding body in a roasting system to roast together with the material, a block mass to be sintered and conglobated is rapidly broken, and a medium is updated on the surface of ore particles. The method of the invention is reasonable in design, is easy to operate and convenient for industrial amplification.

The invention discloses a method for microwave-assisted reverse micelle separation and purification of kidney bean agglutinin, and relates to a separation and purification method of the agglutinin, aiming at solving the problems of low ratio, high cost, more processes and long time for separation and purification of the kidney bean agglutinin. According to the method for the microwave-assisted reverse micelle separation and purification of the kidney bean agglutinin, the agglutinin is directly separated and purified from kidney bean agglutinin water extract; and the method comprises a pre-extraction process and a back extraction process. Under an auxiliary effect of microwave, water-soluble protein in kidney bean is quickly dissolved into the water extract, so that the dissolubility is greatly improved, and the leaching time is shortened. Based on a liquid-liquid extraction principle, the selectivity of extraction is improved, and high-efficiency pre-extraction and back extraction of the kidney bean agglutinin can be realized. By applying a reverse micelle extraction technology, a better separation and purification effect can be achieved with only the pre-extraction and back extraction steps; the method has simple steps and is convenient to operate; and the pre-treatment time can be greatly shortened in combination with microwave assistance so as to save the cost.

The invention belongs to the field of biotechnology. A method for producing iturin through liquid state fermentation with rapeseed meal as a raw material is characterized by including the following steps of firstly, activating strains to obtain activated bacillus subtilis; secondly, conducting shake-flask culture; thirdly, conducting culture in a fermentation cylinder, wherein the bacillus subtilis where shake-flask culture is conducted is fermented in a fermentation medium, and the fermentation conditions include that the inoculum size ranges from 2%(v/v) to 10%(v/v), the pH is 7.0, the fermentation to ventilation ratio is 1-2:1 (vvm), the stirring rotation speed ranges from 300 rpm to 800 rpm, and the fermentation cycle is 72 hours; fourthly, collecting fermentation supernatant and rapeseed meal residues. While high-concentration iturin is obtained through liquid state fermentation with the rapeseed meal as a nitrogen source, the rapeseed meal residues which are appropriately dried can be used as forage protein rich in probiotics and can also be used as bio-organic fertilizers with the bacteriostasis function, and therefore high-valued full utilization of rapeseed meal resources is achieved.

Rebaudioside-KA is a nature-derived novel tetranuclear diterpenoids sweetener compound with low calorific value and high sweetness, has very low content in Stevia rebaudiana, and is difficult to obtain in in a large quantity and in a low cost and green manner. The invention establishes a green biosynthetic method for rebaudioside-KA from rubusoside, which can be easily obtained in a large quantity, as a substrate by fixed-site glycosylation by using glycosyltransferase OleD and a homologous protein thereof. The invention realizes green biological preparation of high-purity rebaudioside-KA through optimizing reaction conditions. The sweetness of rebaudioside-KA is equivalent to the sweetness of rubusoside (over 300 times o sucrose sweetness), and the rebaudioside-KA has pure taste and no bitter after-taste, so that the rebaudioside-KA is more suitable for being used as a sweetener or a correctant in food, beverage, medicament, alcohols, nutritional health products, condiment, chemical necessities, oral hygiene products, cosmetics and other products and fields.

The invention relates to a preparation method of a high transparency silicon dioxide aerogel. The preparation method comprises the following steps: by taking a silicon source, a solvent and water as primary raw materials, a hydrochloric acid solution and a sodium hydroxide solution as a catalyst, and N,N-dimethylformamide as an additive, preparing a gel by means of an acid-base two-step process sol-gel process; and by taking absolute ethyl alcohol or absolute ethyl alcohol added with hexamethyl disilazane as an aging liquid, performing aging and supercritical drying to prepare the blocky silicon dioxide aerogel with good transparency. The preparation method is simple in process and low in cost, and the prepared material has a nanohole structure, the light transparency is 85% above, and the aerogel has a wide application prospect in the field of solar thermal collectors, thermal insulation and lighting windows and the like.