Compound medicament for treating common cold cough and acute/chronic bronchitis, and preparation method thereof

A bronchitis, acute and chronic technology, applied in the field of combined medicines for treating colds, coughs, acute and chronic bronchitis and their preparation, can solve the problems of many clinical treatment observations, few side effects, and few animal experiments and researches, etc.

Active Publication Date: 2009-01-21
陕西关爱制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used traditional Chinese medicine lacks recognized and effective preparations, and the curative effect is generally inaccurate. There are many clinical treatment observations and few animal experiments. In addition, the basic pathogenesis of deficiency in origin and excess in superficiality is ignored in treatment. Ineffective
Therefore, in the treatment of cold and cough, acute and chronic bronchitis, there is still a lack of ideal medicines with good curative effect and little side effects

Method used

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  • Compound medicament for treating common cold cough and acute/chronic bronchitis, and preparation method thereof
  • Compound medicament for treating common cold cough and acute/chronic bronchitis, and preparation method thereof
  • Compound medicament for treating common cold cough and acute/chronic bronchitis, and preparation method thereof

Examples

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preparation example Construction

[0185] The preparation method of the combined medicine comprises the following steps: weighing the above twenty-six medicinal materials, taking Bupleurum, Zanthoxylum bungeanum, Peppermint, Magnolias, Rhizoma Chuanxiong, Angelica, Peucedanum, Asarum, and Ligusticum edulis, and extracting the volatile oil by steam distillation , the distilled liquid is collected in another device; the distilled aqueous solution, herb residues and the rest of ephedra and other seventeen flavors are decocted in water for three times, the first and second time are 1 hour each, and the third time is 40 minutes, the decoction is combined, filtered, and the filtrate is concentrated To the clear paste with a relative density of 1.20 (50°C), add ethanol to make the alcohol content reach 65%, stir well, refrigerate for 24 hours, filter, recycle the ethanol until the filtrate has no alcohol smell, concentrate the filtrate until the relative density is 1.20 (50°C) ℃), add ethanol to make the alcohol conten...

Embodiment 1

[0189] Weighing: 23g ephedra, 23g chuanxiong, 23g angelica, 23g centipeda, 23g white mustard seed, 23g schisandra, 23g licorice, 23g magnolia, 23g tangerine peel, 23g pinellia, 23g perilla seed, 23g bellflower, 23g ligusticum, 23g mint , Peucedanum 23g, Coltsfoot flower 23g, Zanthoxylum bungeanum 23g, Epimedium 23g, Astragalus 23g, Codonopsis 23g, Dried ginger 23g, Peilan 23g, Rush 23g, Morus alba 23g, Bupleurum 23g, Asarum 23g; sucrose 200g, Sorbet Acid 1.5g, polysorbate 80 5g.

[0190] The above twenty-six medicinal materials are taken from Bupleurum, Zanthoxylum bungeanum, Peppermint, Magnolia, Rhizoma Chuanxiong, Angelica, Peucedanum, Asarum, and Ligusticum, and the volatile oil is extracted by steam distillation, and the distillate is collected in another device; the distilled aqueous solution and medicine Add water to decoct the slag and other seventeen flavors such as ephedra for three times, the first and second time each for 1 hour, and the third time for 40 minutes....

Embodiment 2

[0193] Weighing: 22.5g of ephedra, 22g of Chuanxiong, 24g of angelica, 24g of babu, 24g of white mustard seed, 23g of schisandra, 22g of licorice, 23g of magnolia, 23.5g of tangerine peel, 23.5g of pinellia, 23.5g of perilla seed, 22.5g of platycodon, Ben 22.5g, Mint 22.5g, Peucedanum 22.5g, Coltsfoot Flower 22.5g, Zanthoxylum bungeanum 22.5g, Epimedium 24.5g, Astragalus 24.5g, Codonopsis 24.5g, Dried Ginger 24.5g, Perrin 23.5g, Rush 23g, Morus alba 23g skin, 23g Bupleurum, 23g Asarum; 200g sucrose, 1.5g sorbic acid, polysorbate 80 5g.

[0194] The above twenty-six medicinal materials are taken from Bupleurum, Zanthoxylum bungeanum, Peppermint, Magnolia, Rhizoma Chuanxiong, Angelica, Peucedanum, Asarum, and Ligusticum, and the volatile oil is extracted by steam distillation, and the distillate is collected in another device; the distilled aqueous solution and medicine Add water to decoct the slag and other seventeen flavors such as ephedra for three times, the first and secon...

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Abstract

The invention discloses a combination drug for the treatment of colds, coughs and acute and chronic bronchitis and a preparation method thereof. The combination drug includes twenty six medicines, which are ephedra vulgaris, ligusticum chuanxiong hort, angelica, stemona, white mustard seed, shizandra, liquorice, biond magnolia flower, dried orange peel, pinellia tuber, perilla fruit, balloon flower, ligusticum, peppermint, radix peucedani, common coltsfoot flower, pepper, epimedium, raidx astragali, Dangshen, dried ginger, herb of fortune eupatorium, common rush, mulberry root bark, radix bupleuri and asarum. The preparation method is as follows: volatile oil is extracted from radix bupleuri, pepper, peppermint, biond magnolia flower, ligusticum chuanxiong hort, angelica, radix peucedani, asarum and ligusticum by steam distillation, and the distillate is collected in another container; after distillation, the water solution, dregs and other ingredients are decocted for three times after being added with water, the decoction solution is mixed and filtered, the filtered solution is concentrated into clear plaster, ethyl alcohol is added until the amount of alcohol reaches 65 percent, and the mixture is mixed uniformly, frozen and filtered, the ethyl alcohol is recycled, the filtered solution is concentrated again, the ethyl alcohol is added until the amount of alcohol reaches 75 percent, and then the solution is mixed well, frozen and filtered, the ethyl alcohol is recycled until the filtered solution has no smell of alcohol, and the drug is obtained.

Description

technical field [0001] The invention relates to antitussive, expectorant and antiasthmatic medicine, in particular to a combined medicine for treating cold, cough and acute and chronic bronchitis and a preparation method thereof. Background technique [0002] Cold, cough and acute and chronic bronchitis are clinically common respiratory diseases. The prevalence rate in my country is as high as 3% to 4%. The clinical manifestations are cough, sputum, and wheezing as the main symptoms. Cough is a protective reflex, which can promote the expulsion of sputum and foreign bodies in the respiratory tract, and keep the respiratory tract clean and smooth. Acute and chronic bronchitis is essentially an acute and chronic inflammatory disease of the airway. The basic pathology is microbial infection, inflammatory cell infiltration, submucosal tissue edema, increased vascular permeability, smooth muscle hyperplasia, epithelial shedding, and airway response. Sexual hyperactivity stimulat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P11/00A61P11/14
Inventor 杨喜雅
Owner 陕西关爱制药有限公司
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