Novel method for synthesizing prulifloxacin

A compound, a methyl technology, is applied in the new field of synthesis of prulifloxacin, which can solve the problems of product yield decline, difficulty in purification, and high difficulty, so as to reduce the generation of impurities, simplify the post-processing steps, and improve the utilization rate of raw materials Improved effect
CN101418005AInactive Publication Date: 2009-04-29湖南华纳大药厂手性药物有限公司
1 Cites 5 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
湖南华纳大药厂手性药物有限公司
Publication Date
2009-04-29
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a method for synthesizing prulifloxacin of formula (I) with a chemical name of 6-fluoro-1-methyl-7-[4-(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl-1-piperazinyl]-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylicacid. The method for synthesizing prulifloxacin is suitable for industrial production and has the advantages of simple process, high purity and high yield.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention generally relates to a novel synthetic method of quinolone antibacterial drugs, more specifically, the present invention relates to a method for synthesizing the following formula (I) prulifloxacin (prulifloxacin) [chemical name: 6-fluoro-1-methyl- 7-[4-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-1-piperazinyl]-4-oxo-4H-[1, 3] A new method for thiazetidin[3,2-a]quinoline-3-carboxylic acid].

[0002] Background technique

[0003] Since the advent of quinolone antibacterial drugs in the 1960s, they have become a large class of commonly used anti-infection drugs widely used in clinical practice. Due to the advantages of broad antibacterial spectrum, strong antibacterial power, simple structure, convenient administration, no cross-resistance with other commonly used antibacterial drugs, and high curative effect and price ratio, this kind of drugs has attracted more and more attention and has become the field of research and development...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More