Children's chewable tablet for assisting spleen

A technology for Pediatric Fupi and chewable tablets, which is applied in plant raw materials, pill delivery, digestive system, etc., can solve problems such as single dosage form of Pediatric Fupi granules and inconvenience to take.

Inactive Publication Date: 2009-07-22
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to: provide a kind of Xiaoer Fupi chewable tablet and its preparation method. The present invention aims at the shortcomings of existing Xiaoer Fupi granules such as single dosage form and inconvenient taking. It can reduce the burden of drugs on the intestinal tract, and at the same time, because the surface area of ​​the tablet increases after chewing, it can promote the dissolution and absorption of drugs

Method used

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  • Children's chewable tablet for assisting spleen

Examples

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Effect test

Embodiment 1

[0063] Example 1 of the present invention: Atractylodes macrocephala 238g, tangerine peel 60g, hawthorn 300g, Codonopsis 150g, lotus seeds 300g, Poria 120g

[0064] Take Atractylodes macrocephala, dried tangerine peel, hawthorn, Codonopsis pilosula, lotus seeds and Poria cocos six herbs, add 8 times the amount of water to decoct for 1.5 hours, divide the decoction liquid, add 8 times the amount of water to decoct the dregs, and decoct for 2 hours, then take the decoction liquid separately, Combine the two decoctions, filter through 300 mesh, concentrate the filtrate under reduced pressure in three effects to a clear paste with a relative density of 1.10 at 60°C, add 1g of aspartame, stir well, and use it as a binder, then add 47g of mannitol, 24g of Mix dextrin and 24g microcrystalline cellulose as the mother nucleus, pulverize, granulate in one step, dry, and granulate, then add 0.7g magnesium stearate and mannitol fine powder, mix evenly, compress into tablets, coat with film...

Embodiment 2

[0065] Example 2 of the present invention: Atractylodes macrocephala 250g, tangerine peel 150g, hawthorn 150g, Codonopsis 150g, lotus seeds 150g, Poria 120g

[0066] Take Atractylodes macrocephala, tangerine peel, hawthorn, Codonopsis pilosula, lotus seeds and Poria cocos, add 6 times the amount of water to decoct for 0.5 hour, divide the decoction liquid, add 6 times the amount of water to decoct the dregs, and decoct for 1 hour, then take the decoction liquid separately, Combine the two decoctions, filter through 300 mesh, concentrate the filtrate under reduced pressure in three effects to a clear paste with a relative density of 1.05 at 60 ° C, add 0.2 g of aspartame, stir well, and use it as a binder, then add 30 g of mannitol, Mix 10g dextrin and 10g microcrystalline cellulose as the mother nucleus, pulverize, granulate in one step, dry, granulate, then add 0.2g magnesium stearate and mannitol fine powder, mix evenly, compress tablets, coat with film, Make 1000 tablets, n...

Embodiment 3

[0067] Example 3 of the present invention: 250g Atractylodes macrocephala, 50g tangerine peel, 150g hawthorn, 150g Codonopsis pilosula, 150g lotus seeds, 100g Poria cocos

[0068] Take Atractylodes macrocephala, dried tangerine peel, hawthorn, Codonopsis pilosula, lotus seeds and Poria cocos six herbs, add 10 times the amount of water to decoct for 2 hours, divide the decoction liquid, add 10 times the amount of water to decoct the medicinal residues for 3 hours, and divide the decoction liquid, Combine the two decoctions, filter through 300 mesh, concentrate the filtrate under reduced pressure in three effects to a clear paste with a relative density of 1.15 at 60°C, add 1.2g of aspartame, stir well, and use it as a binder, then add 51g of mannitol, Mix 25g of dextrin and 25g of microcrystalline cellulose as the core, pulverize, granulate in one step, dry, granulate, then add 0.9g of magnesium stearate and mannitol fine powder, mix evenly, compress into tablets, and coat with ...

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Abstract

The invention provides an infantile spleen-supporting chewable tablet, which is prepared from rhizoma atractylodis macrocephalae, dried orange peel, hawkthorn, radix codonopsitis, lotus and tuckahoe which are added with proper amount of auxiliary materials. Compared with the prior art, the chewable tablet is portable and convenient to take without water, is chewed in the oral cavity and then is swallowed so as to reduce the burden to intestinal canals caused by the medicine, and has larger surface area after being chewed so that the dissolution and the absorption of the medicine can be promoted. Besides, the chewable tablet improves the functions of strengthening immunity and promoting digestion, has better curative effect, and improves the smoothness of taking medicine.

Description

Technical field: [0001] The invention relates to a children's spleen-supporting preparation and a preparation method thereof, belonging to the technical field of traditional Chinese medicine pharmacy. Background technique: [0002] Xiaoer Fupi Granules is recorded in the "National Compilation of Chinese Patent Medicine Standards" in the Oncology Pediatrics Subvolume. It can strengthen the spleen and stomach and help digestion. It is used to treat children with spleen and stomach qi deficiency, indigestion, and emaciation. This medicine is a medicine for invigorating the spleen and stomach and helping digestion. Taking too much water will have a certain impact on the curative effect. And granules need to be taken after a large amount of water dissolving, so its curative effect is affected, not quite ideal. Chewable tablets are more convenient to carry and take, and do not need to be washed with water. And the chewable tablet is chewed in the mouth and then swallowed, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/20A61P1/14
Inventor 叶湘武韦莹张梅
Owner GUIZHOU YIBAI PHARMA CO LTD
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