Dioscorea nipponica effective components for treating acute gouty arthritis and extracting method thereof

An effective part, acute gout technology, applied to the effective part of traditional Chinese medicine, the effective part of panshanlong in the treatment of acute gouty arthritis, can solve the problem of not having the ability to reduce uric acid in the patient's blood, and achieve the purpose of alleviating inflammation, reducing uric acid, and curative effect Good results

Inactive Publication Date: 2009-09-23
刘树民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing pangolinus extracts or effective parts only have good anti-inflammatory and analgesic effects on rheumatism and rheumatoid arthritis, but do not yet have the effect of reducing uric acid in th

Method used

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  • Dioscorea nipponica effective components for treating acute gouty arthritis and extracting method thereof
  • Dioscorea nipponica effective components for treating acute gouty arthritis and extracting method thereof
  • Dioscorea nipponica effective components for treating acute gouty arthritis and extracting method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0015] Example 1

[0016] Cut 1000g dry roots and rhizomes of Pterocarpus paniculata into slices, crush, soak for 30 minutes, add 6 times the weight of water, and decoct for 1 hour to obtain a decoction; the decoction is concentrated to 1g / ml on the AB-8 type macroporous adsorption resin column. Elute with distilled water until it is colorless, collect the eluate to obtain component I; then elute with 30% ethanol until it is colorless, collect the eluate to obtain component II; recover the ethanol, and then eluate with 50% ethanol until there is no Color, collect the eluate, recover ethanol to obtain component III; then eluted with 70% ethanol until colorless, collect the eluate, and recover ethanol to obtain component IV.

Example Embodiment

[0017] Example 2

[0018] Cut 1000g of dry roots and rhizomes of Pterocarpus paniculata into slices, crush, soak for 30 minutes, add 8 times the weight of water, decoct for 1 hour, decoc 2 times, combine the decoction to obtain the decoction; concentrate the decoction to 2g / ml on D101 Type macroporous adsorption resin column, eluted with 6 times distilled water, discarded the eluate, and then eluted with 8 times 30% ethanol. Collect the eluate and recover the ethanol to obtain component II, and then eluted with 50% ethanol. When it is colorless, collect the eluate and recover ethanol to obtain component III; then eluted with 70% ethanol until it is colorless, collect the eluate, and recover ethanol to obtain component IV.

Example Embodiment

[0019] Example 3

[0020] Cut 1000 g of the dried roots and rhizomes of Pterocarpus paniculatus, crushed, add 70% ethanol 3 times the weight, and extract 4 times under reflux, combine the extracts, and recover the ethanol to obtain the extract of the effective parts of Pterocarpus paniculatus (component V).

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Abstract

The invention discloses an extract of dioscorea nipponica effective components for treating acute gouty arthritis and an extracting method thereof. The extract is prepared by the following steps of: crushing the dioscorea nipponica, then using water for decoction, extracting, collecting water decoction liquid and filtering; or using 10-95% ethanol to conduct extracting after crushing the dioscorea nipponica, then collecting ethanol extraction and recycling the ethanol. The dioscorea nipponica effective components for treating acute gouty arthritis are rich in active ingredients and have pharmacological actions of lowering uric acid, anti-inflammation and analgesia. The effective components not only can relieve inflammatory reactions of swelling thermal pain in acute stage, but also can lower uric acid level in blood aiming at pathogenesis, treat the primary and the secondary aspects simultaneously for gout and can be used for preparing medicaments with good curative effects for preventing and treating acute gouty arthritis safely and reliably. The extracting technology of the effective components is simple, does not need high-temperature or high-pressure or special equipment, and has safety, easy operation and low cost.

Description

technical field [0001] The invention relates to an effective part of a traditional Chinese medicine, in particular to an effective part of pangolinus for treating acute gouty arthritis. The method for extracting the effective part of the invention belongs to the field of traditional Chinese medicine for treating gouty arthritis. Background technique [0002] Studies have shown that the prevalence of gout is rising rapidly in both developed and developing countries. The first symptom of gout is acute gouty arthritis. If it is not properly treated, it will not only bring great pain to the patient, but also easily lead to serious consequences such as joint deformity, kidney stones, and kidney damage. Therefore, acute gouty arthritis has become a threat to human health. A serious disease for which there is still no cure. Therefore, there is an urgent need to find effective Chinese medicines for the prevention and treatment of acute gouty arthritis, so as to control the occurren...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P19/06A61P19/02A61K125/00
Inventor 刘树民姚丽于书仪
Owner 刘树民
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