35 results about "Gouty arthropathy" patented technology

The invention relates to an oral medicinal combination and the preparing method, using Epimedium Herb, Coix Seed, Tangerine Peel, Perilla Leaf, Common Floweringqince Fruit and other Chinese drugs as raw materials, first decocting these raw materials to extract fragrant liquid, then decocting twice and filtering, combining the filtrate, fragrant liquid and auxiliaries and making the mixture into different preparations. It can remove damp and dredge meridian, and eliminating rheumatism and stop pain, and is used to relieve joint gall of toes and metatarsi caused by gout caused by damp and corruption. In addition, the curative effect test verifies that it can prohibit joint gall of sole of the foot of a rat caused by sodium urate (MSU), remarkably reduce white cells in joint liquid of a rabit with acute arthritis induced by MSU, remarkably prohibit the foot swelling of a rat caused by carageen glue and the ear swelling of a mouse caused by dimethylbenzene, and obviously prohibit the forming of granulation swelling of a rat.

The invention relates to the technical field of medicaments and particularly relates to application of a pawpaw total phenolic acid extract in preparation of arthritis prevention and treatment medicaments or food, which is characterized in that the arthritis is gouty arthritis or rheumatoid arthritis. According to the invention, a pawpaw total phenolic acid extract is prepared from pawpaw fruit, and according to component analysis, the pawpaw extract comprises the following main components: protocatechuic acid, chlorogenic acid and other phenolic acid compounds, wherein the protocatechuic acid accounts for 30% to 35%, the chlorogenic acid accounts for 20% to 25%, and the phenolic acid compounds account for 50% to 60% of the pawpaw extract. Therefore, the product is called the pawpaw total phenolic acid extract. Animal experiments prove that the pawpaw total phenolic acid extract disclosed by the invention has obvious activity for preventing and treating the gouty arthritis or the rheumatoid arthritis, thus being used for preparing the medicament or food for preventing and treating the gouty arthritis or the rheumatoid arthritis.

The invention discloses applications of cannabidiol in preparing medicines for treating gouty arthritis. For the first time, the inventor finds that cannabidiol has the effect of obviously reducing creatinine and uric acid in serum of mice suffering from hyperuricemia, so that the hyperuricemia can be prevented and treated; meanwhile, cannabidiol can regulate the cell factors of the body, effectively resist inflammation, and alleviate gouty arthritis symptoms, and has treatment and prevention effects for the gouty arthritis. The invention further provides medicinal preparations of cannabidiol for treating gouty arthritis and corresponding medicinal dosage forms of the medicinal preparations, the medicines with different dosage forms used clinically can be prepared with a conventional preparation method, and the use is convenient.

The invention discloses application of hemp extract in preparation of medicine for treating gouty arthritis. An inventor finds that after tetrahydrocannabinol and cannabidiol are mixed according to a specific ratio, the effects of remarkably reducing creatinine and uric acid in hyperuricemia mouse serum and preventing hyperuricemia are achieved for the first time. Meanwhile, organism cell factors are adjusted, inflammation is effectively resisted, gouty arthritis symptoms are relieved, and treatment and prevention effects are achieved for gouty arthritis. The invention further provides a pharmaceutical preparation of the hemp extract for treating gouty arthritis and a dosage form corresponding to the pharmaceutical preparation. The medicine which is used clinically and has various different dosage forms can be prepared through a conventional preparation method, and use is convenient.

The invention discloses application of a cannabinoid compound in preparation of medicine for treating gouty arthritis. The inventor finds that the cannabinoid compound has the function of remarkably reducing creatinine and uric acid in serum of a hyperuricemia mouse for the first time, and hyperuricemia is avoided. Meanwhile, cell factors of an organism are adjusted, effective inflammation resistance are achieved, gouty arthritis symptoms are relieved, and the functions of treating and preventing gouty arthritis are achieved. The invention further provides a medicinal preparation of the cannabinoid compound for treating gouty arthritis and a corresponding dosage form of the medicinal preparation, clinically used medicines of different dosage forms can be prepared through a conventional preparation method, and use is convenient.

The invention relates to a pharmaceutical composition used for preventing and treating urarthritis and hyperuricemia. The pharmaceutical composition comprises the following components in parts by weight: 7-15 parts of fringed pink, 5-10 parts of radix clematidis and 5-13 parts of large-leaved gentian. The invention provides the pharmaceutical composition used for preventing and treating urarthritis and hyperuricemia, and the pharmaceutical composition can lower blood uric acid content of gout patients, alleviate pain, prevent uric acid from rising and restore and improve the metabolism function of the patients and has no toxic and side effects.

The invention discloses bath liquid with an efficacy of alleviating gouty arthritis. The bath liquid is prepared from sodium bicarbonate thermal spring water and eight wild Chinese herbal medicines including Herba Lycopodii, Herba Blumeae Balsamiferae, Herba Bidentis Bipinnatae, Radix Ilicis Pubescentis and the like. The bath liquid can be used for foot bath or body bath of gout patients and is capable of well alleviating gouty arthritis and avoiding liver-kidney injuries caused by medicines.

The present invention relates to Chinese herbal medicine for treating gouty arthritis, and is especially one kind of externally applied medicine for treating gouty arthritis and its preparation process. The externally applied medicine is prepared with 11 kinds of Chinese medicinal materials, including ash bark, ant, giant knotweed, Chuanxiong rhizome, red peony root, cassia twig, etc in certain weight proportion. The present invention has the features of convenient treatment, low cost, fast effect, no irritation and no side effect.

The invention provides a traditional Chinese medicine composition for treating hyperuricemia and gouty arthritis, which comprises the following ingredients in parts by weight: 500-1500 parts of Smilax smilax, 300-900 parts of Mianzi, 100-500 parts of honeysuckle, 50-50 parts of vinegar Corydalis 250, Shanzi mushroom 50-150, and medicinal excipients. Provided is a preparation method of a traditional Chinese medicine composition for treating hyperuricemia and gouty arthritis of rheumatic stagnation-heat type, and is used for treating gout and hyperuricemia. The effect of the present invention is that the traditional Chinese medicine composition overcomes the disadvantages of traditional dosage forms such as decoction, adopts the method of water extraction, retains the active ingredients with clinical curative effect in the composition, and adopts high-efficiency dynamic circulation extraction equipment to extract effective ingredients, to ensure its clinical efficacy. The preventive and therapeutic effects on hyperuricemia and rheumatism-heat-type gouty arthritis are obviously better than similar drugs.

The invention relates to medicines, in particular to a traditional Chinese medicine for treating acute gouty arthritis and aims at solving the problems that a specific therapy with special effect does not exist in western modern medicines, side effect is great and result is not satisfactory. The traditional Chinese medicine for treating the acute gouty arthritis is prepared from the following raw materials in weight: 10-20g of rhizoma atractylodis, 5-15g of cortex phellodendri, 20-40g of medicinal cyathula root, 20-40g of semen coicis, 5-15g of cortex moutan, 10-20g of red peony root, 20-40g of yam rhizome, 20-40g of rhizoma smilacis glabrae, 15-25g of radix clematidis, 10-20g of prepared rhizoma cyperi, 20-40g of dioscorea nipponica makino, 15-25g of pawpaw, 10-20g of born hawthorn, 10-20g of safflower, 10-20g of dried body of ground beetle, 10-20g of earthworm, 20-30g of rhizoma corydalis and 5-10g of born liquorice. The traditional Chinese medicine for treating the acute gouty arthritis has the effects of resolving blood stasis and eliminating stagnation as well as promoting diuresis, accords with traditional Chinese medicine theory, is based on pathogenesis characteristics of the acute gouty arthritis and is definite in curative effect and high in safety.

The invention provides a traditional Chinese medicine preparation for preventing acute attack of gouty arthritis, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine preparation for preventing acute attack of the gouty arthritis comprises raw material medicines as follows: 6 g-10 g of Chinese angelica, 6 g-10 g of dried tangerine peels, 6 g-10 g of bulbs of thunberg fritillary, 6 g-10 g of Chinese honeylocust spines, 6 g-10 g of Indian iphigenia bulbs,12 g-15 g of red peony roots, 12 g-15 g of snakegourd roots, 12 g-15 g of rhizoma atractylodis, 12 g-15 g of amur corktree bark, 12 g-15 g of radix stephaniae tetrandrae,12 g-15 g of oriental waterplantain rhizomes, 12 g-15 g of radix cyathulae, 4 g-6 g of frankincense, 4 g-6 g of myrrh, 4 g-6 g of liquorice and 3 g-5 g of pangolins. The traditional Chinese medicine preparation for preventing acute attack of the gouty arthritis has a remarkable curative effect, and clinical tests prove that the preparation has no toxic or side effects, is high in curative ratio, low in treatment cost, low in recurrence rate and suitable for being applied and popularized.

The invention relates to an external preparation, and in particular relates to an external preparation for treating gouty arthritis by using Chinese herbal medicine, and belongs to the technical field of Chinese herbal medicine preparations. The external preparation is prepared from raw materials of edible tulip, raw rhubarb, golden cypress, nux vomica, short-pedicel aconite root and borneol. The external preparation provided by the invention is based on study and treatment principles of traditional Chinese medicines to pathogenesis of gouty arthritis with reference to achievements in scientific researches on external treatment of gouty arthritis by theoretical research of modern Chinese medicines. The preparation is combined according to the formula of theory of traditional Chinese medicine, so that the preparation in the medicament has the effects of clearing heat and promoting diuresis, promoting blood circulation to remove meridian obstruction and relieving swelling and pain so as to improve the microcirculation disturbance of human body. The external preparation has the characteristics of external treatment, direct reach to focus, simpleness in use, low cost and remarkable curative effect, and solves the problems that the treatment effect to the focus by oral delivery of medicines to treat gouty arthritis is not remarkable, side effects to liver, kidney, stomach and the like of the human body are generated, operative treatment cannot thoroughly eliminate the gouty arthritis, and the patients are painful and the treatment expense is high.

The invention relates to a traditional Chinese medicine composition for the treatment of the acute attack of gouty arthritis. The traditional Chinese medicine composition comprises, by weight, 10 g of cortex phellodendri, 10 g of rhizoma atractylodis, 30 g of coix seeds, 15 g of achyranthes bidentata, 12 g of folium isatidis, 12 g of polygonum cuspidatum, 10 g of rhubarb, 30 g of salviae miltiorrhizae, 30 g of smilax glabra, 15 g of fish poison yam, 30 g of honeysuckle stem, 10 g of rhizoma chuanxiong, 30 g of honeysuckle, 15 g of scrophulariae, 10 g of angelica pubescens, 15 g of dandelion, 12 g of bunge corydalis herb, 15 g of lily, 15 g of pleione bulbocodioides and 12 g of radix glycyrrhizae. The traditional Chinese medicine composition for the treatment of the acute attack of gouty arthritis has the advantages that a good treatment effect is possessed on the treatment of the acute attack of gouty arthritis, the effects of clearing away heat and toxic materials, dispersing blood stasis and dredging collateral, clearing damp and rushing down turbid damp and relieving swelling and pain are possessed, and effective treatment effect is possessed on the heat toxin stasis type gouty arthritis; the clinical cure rate is high, the cure rate is 59.09%, and the total effective rate is 93.64%; the improvement of symptoms is obvious, the pain of a patient is relived greatly, and the living quality of the patient is improved.

The invention relates to the field of natural medicaments, in particular to application of a philippine violet herb total phenol extract to treatment of hyperuricacidemia. Pharmacological tests prove that joint swelling of gouty arthritis of rats due to sodium urate crystals can be relieved obviously and the tread treatment of the rats can be improved by intragastric administration of the philippine violet herb total phenol extract. The philippine violet herb total phenol extract has the obvious inhibitory effect on hyperuricemia and urate nephropathy of mice due to a uricase inhibitor, adenine and ethambutol, but does not exert obvious influence on urinary volume, so the philippine violet herb total phenol extract has the effect of promoting the excretion of uric acid and has no effect of diuresis; and due to the single function of the philippine violet herb total phenol extract, doctors do not need to consider the influence of diuretic factors on patients during clinical application.

The invention discloses application of industrial cannabinoid in preparing drugs for treating gouty arthritis. The inventor finds that the cannabinoid prepared through industrial hemp has the effect of significantly reducing creatinine and uric acid in serum of mice with hyperuricemia and prevents and treats hyperuricemia for the first time; meanwhile, the cannabinoid can regulate cell factors of bodies, effectively resist inflammation and relieve symptoms of the gouty arthritis and has obvious treating and preventing effects on the gouty arthritis. The invention further provides a pharmaceutical preparation of the industrial cannabinoid for treating the gouty arthritis and corresponding pharmaceutical dosage forms of the pharmaceutical preparation. The industrial cannabinoid can be prepared into clinically applied drugs of different dosage forms through a conventional preparation method, and use is convenient.

The invention discloses a traditional Chinese medicine composition for treating gouty arthritis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5 to 13 parts of honey-fried licorice root, 10 to 20 parts of baked radix aconiti carmichaeli, 10 to 20 parts of rhizoma atractylodis macrocephalae, and 12 to 24 parts of cassig twig. A preparation method of the traditional Chinese medicine composition for treating the gouty arthritis comprises the following steps: step I: selecting materials; step II: soaking; step III: primarily decocting; step IV, secondarily decocting; and step V, filtering. The traditional Chinese medicine composition has the effect for warming Yang, dispelling the cold, eliminating the dampness, and freeing numbness, can apparently improve the gouty arthritis, and is definite, rapid and stable in curative effect and is nontoxic and free from side effects.

The invention discloses a fresh-juice hard capsule for treating the gouty arthritis. The fresh-juice hard capsule comprises fresh juice and a hard capsule shell. Various kinds of liquid in the fresh juice are hard frozen at the temperature lower than -30 DEG C to be in ice ball shapes and wrapped in Ooho spherical-surface films; the multiple pellets of fresh juice in the ice ball shapes are arranged in the hard capsule shell; the diameter of the ball shapes of the fresh juice in the ice ball shapes ranges from 0.1 cm to 0.5 cm. The fresh juice comprises, by weight, 30 parts to 35 parts of fresh radish juice, 25 parts to 30 parts of fresh plantain herb juice, 20 parts to 25 parts of fresh longhairy antenoron herb juice and 15 parts to 20 parts of honey, wherein the total number of the parts of the components is one hundred. According to the fresh-juice hard capsule, the exact curative effect of the fresh juice on the gouty arthritis is kept, the toxic and side effects generated during modern medicine treatment are avoided, the defect that a patient can not accept traditional Chinese medicine decoction treatment easily is overcome, and the defects that in the existing pharmaceutical technology, when the water content of liquid medicine exceeds 50%, the hard capsule shell will be softened or dissolved, and the liquid medicine is not suitable for being prepared into hard capsules are overcome; in addition, convenience is brought to storing, transporting and taking; meanwhile, the various kinds of liquid in the fresh-juice hard capsule are wrapped by the Ooho spherical-surface films respectively to be mixed and packaged according to the part-of-weight ratio, and therefore influences, possibly caused by the stability generated when the fresh juice is directly compounded and mixed, on the product quality are avoided.

The invention discloses a traditional Chinese medicine composition for treatment of gouty arthritis and / or hyperuricemia, wherein the traditional Chinese medicine composition is prepared from rhizomadioscoreae colletii, herba desmodii styracifolii, lygodium japonicum, radix cudramiae, endothelium corneum gigeriae galli, folium pyrrosiae, leonurus, plantain herb, radix achyranthis bidentatae, poria cocos and fructus aurantii immaturus. The traditional Chinese medicine composition is prepared from a variety of traditional Chinese medicinal materials and has the functions of removing dampness for causing diuresis, promoting blood circulation and removing swelling, removing blood stasis and dredging collaterals, tonifying kidney and liver, strengthening muscles and bones and the like, and caneffectively treat gouty arthritis and / or hyperuricemia. The traditional Chinese medicine composition can also be made into capsules, granules, oral liquids and other preparations, can be convenient to take and carry, meets the taking and carrying of patients in different illness conditions, and is applicable to a wide range of people. In addition, the traditional Chinese medicine composition hasscientific and reasonable formula, small side effects, simple preparation method and low preparation cost, can greatly alleviate the body and economic burden of patients, and has great promotion value.

The invention discloses a tea substitute beverage capable of treating heat syndrome gouty arthritis. The tea substitute beverage is characterized by being prepared from the following ingredients in parts by weight: 2 parts of flos lonicerae, 2 parts of radix angelicae sinensis, 1 part of licorice root, 1 part of radix puerariae, 1 part of herba portulacae, 1 part of coix seed, 1 part of semen hoveniae and 1 part of poria cocos. According to the tea substitute beverage, the defects that traditional decoction is complex in decocting, is inconvenient in carrying and the like are overcome, the teasubstitute beverage can be drunk for multiple times at any time for a long time, is capable of regulating and treating slowly, heat syndrome can be alleviated, the gouty arthritis can be effectivelytreated, and in addition, the repeated attack of the gouty arthritis can be avoided.

The invention relates to the field of traditional Chinese medicine, and discloses a pain relieving and serum uric acid decreasing medicinal tea for preventing and treating gouty arthritis. The tea comprises the following components in parts by weight: 10-14 parts of cassia twig, 10-14 parts of honeysuckle stem, 8-12 parts of large-leaved gentian, 8-12 parts of radix clematidis, 8-12 parts of crotalaria sessiiflora, 8-12 parts of rhizoma smilacis glabrae, 6-10 parts of grifola, 6-10 parts of semen plantaginis, 6-10 parts of rhizoma alismatis, 4-8 parts of radix paeoniae alba, and 4-8 parts of radix bupleuri. The pain relieving and serum uric acid decreasing medicinal tea is suitable for paints with gouty arthritis and hyperuricemia and has the functions of relieving acute gout caused redness, swelling and pain of joints and other symptoms and also has the effect of decreasing serum uric acid.

The invention discloses a pharmaceutical composition for preventing and curing gouty arthritis and functions thereof. The composition is made of active ingredients and auxiliary materials, wherein the active ingredients include homopterocarpin. The pharmaceutical composition can relieve foot swelling caused by gouty arthritis, reduces the content of inflammatory factors FGE2 and NO in swollen foot tissue, and accordingly relieves inflammatory reactions of the foot tissue.

The invention discloses a medicine for curing gouty arthritis. The medicine for curing gouty arthritis is characterized by being prepared from the following substances according to mass ratio: 3-7 parts of radix rehmanniae, 10-15 parts of radix clematidis, 5-10 parts of sumiregusa, 5-10 parts of Ligusticum chuanxiong Hort., 8-15 parts of herba epimedii, 5-10 parts of drynaria rhizome, 5-10 parts of radix curcumae longae, 5-10 parts of bombyx batryticatus, 5-10 parts of ground beeltle, 5-10 parts of ophidia and the like. The medicine provided by the invention is applicable to treatment on various gouty arthritis, has no toxic or side effects, and is excellent in application effect and low in cost.

A Chinese medicine for treating gouty arthritis is prepared from grain spirit and 14 Chinese-medicinal materials including spatholobus stem, earthworm, clematis root, liquorice root, etc. Its advantages are high cure rate up to more than 80%, high total effective rate up to 100%, and low cost.

The invention discloses a medicine composition for treating gouty arthritis and application thereof. The medicine composition is prepared from, by weight, 11-19 parts of rhizoma atractylodis, 11-19 parts of banana peels, 26-34 parts of kudzu vine roots, 26-34 parts of yam rhizomes, 5-9 parts of stiff silkworms, 11-19 parts of Indian iphigenia bulb, 9-15 parts of mulberry twigs and 12-18 parts of pagodatree pod. The medicine composition has the effects of inhibiting uricopoiesis, promoting uric acid excretion and relieving local swelling and pain and also avoids the toxic and side effects, such as gastrointestinal reaction, kidney function affection and decrease of white blood cells, produced in western medicine treatment.

The invention relates to the technical fields of natural pharmaceutical chemistry and medicines and discloses application of a stephania hainanensis extract in preparation of a preparation used for treating gouty arthritis. The stephania hainanensis extract can obviously reduce joint swelling degree of a gouty arthritis rat, reduce a rat spleen index and lower levels of rat leukocytes, neutrophile granulocytes and lymphocytes, uric acid level in rat blood is also obviously lowered, and therapeutic effect on the gouty arthritis is obvious. The stephania hainanensis extract can be directly used and also can be used after being added with corresponding auxiliary materials and prepared into a preparation in a certain dosage form.

Provided is an application of red dragon analgesic tablets in treating anti-gout arthritis. Through experiments, it is found that the red dragon analgesic tablets can remarkably reduce the serum uricacid level of animals with low or high uricacidemia, obviously improve pathological changes such as joint edema, joint synovial thickening and joint cartilage proliferation of the experiment animals,remarkably inhibit emigration of the leukocyte and PGE2 of rats with gout arthritis, lower the inflammation index and improve the dysfunction score of the animals with gout.

The invention discloses substituting tea drink for treating cold syndrome gouty arthritis. The substituting tea drink comprises the following components in parts by weight: 2 parts of radix angelicaesinensis, 1 part of rhizoma dioscoreae, 1 part of poria cocos, 1 part of radix ginseng, 1 part of dried tangerine peel, 1 part of coix chinensis, 1 part of semen euryales, 1 part of black-tail snake,and 1 part of raw oyster shell. The shortcomings of tedious decoction process and inconvenience to carry and the like of the traditional decoction are overcome; the substituting tea drink can be drunkfor a long term at any time to slowly regulate the cold syndrome gouty arthritis, so that not only is the cold syndrome relieved, but also gouty arthritis is effectively treated; and repeated attacksof gouty arthritis can be avoided.