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Plant extract used for preparing medicine for treating asthma and application thereof

A plant extract and extract technology, applied in the direction of drug combination, plant raw materials, medical preparations containing active ingredients, etc., can solve the problem that the curative effect of the original prescription has not been fully exerted, the extraction and refining process is backward, and the effective ingredients are not clear and other problems, to achieve the effect of retaining active ingredients, highly targeted treatment, and remarkable curative effect

Inactive Publication Date: 2009-09-30
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Through in-depth investigation and research, it is found that the preparation has the following defects: the extraction and refining process is backward (using the traditional water extraction and alcohol precipitation method), the active ingredients are not clear, the dosage is large, it is inconvenient to take, and the curative effect is not exact
Due to the above reasons, the curative effect of the original prescription has not been fully exerted.

Method used

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  • Plant extract used for preparing medicine for treating asthma and application thereof
  • Plant extract used for preparing medicine for treating asthma and application thereof
  • Plant extract used for preparing medicine for treating asthma and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Respectively crush Rhododendron aurantii and Aodi tea into 20 mesh coarse powder.

[0044] Use 60% ethanol to reflux extract 7 kg of crushed Rhododendron viola powder and further purify it with macroporous adsorption resin, add 60% ethanol 8 times, extract 3 times, each time for 0.5 hours; concentrate the extract to dry extract, add dry extract Dissolve 12 times the amount of ethanol in the ointment, filter, repeat 3 times, concentrate the filtrate to dryness, add 5 times the amount of water to dissolve, apply macroporous adsorption resin, elute with water 13 times the volume of the resin bed, discard the washing solution, and then use Elute with 20% ethanol 8 times the volume of the resin bed, discard the 20% ethanol eluate, and finally elute with 30% ethanol 10 times the volume of the resin bed, collect the 30% ethanol eluate, evaporate the ethanol, and dry under reduced pressure instant;

[0045] Extract 3 kg of Aodicha powder with 60% ethanol under reflux and furth...

Embodiment 2

[0049] Respectively crush Rhododendron aurantii and Aodi tea into 20 mesh coarse powder.

[0050] Extract 6 kg of crushed rhododendron powder with 70% ethanol under reflux and further purify with macroporous adsorption resin, add 75% ethanol 10 times, extract 3 times, 0.5 hours each time; concentrate the extract to dry extract, add dry extract Dissolve 7 times the volume of the ointment in ethanol, filter, repeat 2 times, concentrate the filtrate to dryness, add 5 times the volume of water to dissolve, apply macroporous adsorption resin, elute with water 9 times the volume of the resin bed, discard the washing solution, and then use Elute with 10% ethanol 9 times the volume of the resin bed, discard the 10% ethanol eluate, and finally elute with 35% ethanol 11 times the volume of the resin bed, collect the 35% ethanol eluate, evaporate the ethanol, and dry under reduced pressure instant;

[0051] Extract 4kg of Aodicha powder with 70% ethanol under reflux and further refine t...

Embodiment 3

[0055] Respectively crush Rhododendron aurantii and Aodi tea into 20 mesh coarse powder.

[0056] Extract 2 kg of crushed Rhododendron viola powder with 80% ethanol under reflux and further purify it with macroporous adsorption resin, add 75% ethanol 8 to 10 times, extract twice for 1.5 hours each time; concentrate the extract to dry extract, add Dissolve 8 times the amount of dry extract in ethanol, filter, repeat 4 times, concentrate the filtrate to dryness, add 10 times the amount of water to dissolve, apply macroporous adsorption resin, elute with water 7 times the volume of the resin bed, discard the washing solution, Then elute with 5% ethanol of 13 times the volume of the resin bed, discard the 5% ethanol eluate, and finally elute with 25% ethanol of 10 times the volume of the resin bed, collect the 25% ethanol eluate, evaporate the ethanol to the fullest, reduce pressed to dry;

[0057] Extract 8 kg of Aodicha powder with 80% ethanol under reflux and further refine th...

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Abstract

The invention provides a plant extract used for preparing medicine for treating asthma, which is a mixture formed by rhododendron mariae extract and Japanese ardisia extract according to any proportion, the mixture is an extract prepared after the rhododendron mariae is mixed with the Japanese ardisa or is prepared by the steps of preparing the rhododendron mariae extract and the Japanese ardisia extract and before mixing the two extracts. The invention also provides the application of the extract in the preparation of the medicine for treating asthma; the extract and pharmaceutically receivable minor ingredients are made into the medicine preparation, and the medicine preparation can be dripping pills, troche, capsule, granules or other common medicine preparations. The extract has less components, very simple preparation process, more scientific and reasonable prescription, strong specific treatment and remarkable treatment effect, uses the traditional famous prescription as support, and combines the traditional Chinese medicine theory with years of clinical experiences.

Description

technical field [0001] The invention relates to a preparation method and application of a plant extract used for preparing anti-asthma drugs, more specifically a preparation method and application of a Chinese medicinal material extract used for preparing anti-asthma drugs. Background technique [0002] Asthma is one of the common chronic diseases in the world. There are about 150 million asthma patients in the world. In the past two decades, the incidence rate in the world has been gradually increasing. It is of great significance to study its treatment. Asthma is a common symptom of respiratory discomfort, can appear in many diseases, and is stubborn and difficult to heal. Its formation has many reasons, and its cause of disease has the difference of exogenous pathogenic factor and internal injury, and pathogenesis has the branch of deficiency and excess of cold and heat, and cold, smoking, drinking etc. all can cause cough and asthma. Western medicine mostly adopts antib...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/45A61P11/06
Inventor 冯毅凡石忠峰孟青韩亮
Owner GUANGDONG PHARMA UNIV
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