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Egg yolk immunoglobulins oral and throat spraying agent and preparation method thereof

A technology of egg yolk immunoglobulin and spray, which is applied in aerosol delivery, respiratory diseases, non-active ingredients of polymer compounds, etc., can solve problems such as serious side effects, increase the difficulty of treatment, and allergic reactions, and achieve long-term Enhanced efficacy and stability, improved compatibility and stability, and high antibody activity

Inactive Publication Date: 2009-11-18
浙报数字文化集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Although the use of antibiotics and anti-inflammatory enzymes has a good effect, there are serious disadvantages. Long-term use will lead to the emergence of drug-resistant strains and cause antibiotics to fail; Great difficulty in treatment; third, antibiotics and anti-inflammatory enzymes will indiscriminately eliminate the beneficial bacteria in the mouth and throat, resulting in "dysbacteria", destroying the micro-ecological balance, and even aggravating the condition; fourth, frequent use of antibiotics and anti-inflammatory enzymes can cause diarrhea, allergic reactions, fungal infections and other side effects
If antibiotics and anti-inflammatory enzymes are used for underage children, the side effects caused by the above-mentioned disadvantages will be more serious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Prepare egg yolk immunoglobulin oral throat spray according to the following formula: a total of 100 parts by weight, wherein:

[0017] Yolk immunoglobulin against respiratory infection 0.01% by weight

[0018] Stabilizer Tween-20 1.0% by weight

[0019] Dispersant poloxamer 1.0% by weight

[0020] Protective agent gelatin 1.0% by weight

[0021] Humectant Glycerin 2.0% by weight

[0022] Deionized water 94.99% by weight

[0023] Take the above formula, operate under room temperature and clean conditions, successively add 10.0 grams of poloxamer and 10.0 grams of gelatin to 949.9 grams of deionized water, stir to disperse them evenly to form the water phase (A); in addition, add 10.0 grams of Tween -20 and 20.0 grams of glycerin are added under stirring conditions, dispersed and mixed evenly to form the oil phase (B). Slowly add the oil phase (B) into the water phase (A) under agitation and mix evenly; then add 0.1 g of anti-respiratory tract infection egg yolk imm...

Embodiment 2

[0025] Same as Example 1, except that 50.0 grams of poloxamer, 20.0 grams of gelatin, 50.0 grams of Tween-20, 50.0 grams of glycerin, 5 grams of anti-respiratory tract infection egg yolk immunoglobulin and 825 grams of deionized water. The prepared spray product has higher biological activity and is more suitable for consumers who have long-term smoking with a strong mouthfeel or significant clinical symptoms.

Embodiment 3

[0027] Same as Example 1, the difference is in order to adjust the taste of the oral and throat spray, so that it has a taste that people can usually adapt to when it is in the mouth, and is more suitable for consumers who have long-term smoking with a strong mouthfeel or significant clinical symptoms. In the above formula Add 1.0 g of aspartame, 5.0 g of natural essence or mint essence. The resulting spray product has a stronger breath freshness.

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PUM

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Abstract

The invention relates to an egg yolk immunoglobulins oral and throat spraying agent and a preparation method thereof. The egg yolk immunoglobulins oral and throat spraying agent comprises the following components according to the weight percent: 0.01-0.5 of egg yolk immunoglobulins, 1.0-5.0 of stabilizing agent, 1.0-5.0 of dispersing agent, 1.0-2.0 of protective agent, 2.0-5.0 of humectants, and the balance of de-ionized water. the preparation method comprises the following steps: the dispersing agent and the protective agent are sequentially added into the de-ionized water under the conditions of room temperature and cleanness, and are uniformly mixed to be water phase (A); the stabilizing agent and the humectants are sequentially added under the mixing condition, and are dispersed and mixed to oil phase (B); the oil phase (B) is slowly added into the water phase (A) under the mixing condition, the oil phase (B) and the water phase (A) are uniformly mixed, then the egg yolk immunoglobulins is added into liquid materials and is uniformly mixed, and the packaging is performed after the detection is qualified. The egg yolk immunoglobulins oral and throat spraying agent is safe, and has special good effect and special long effect.

Description

technical field [0001] The invention relates to a yolk immunoglobulin oral and throat spray and a preparation method thereof, in particular to a safe, specific, high-efficiency and long-acting specific biological agent oral and throat spray for anti-pharyngitis and upper respiratory tract infection Spray and its preparation method. Background technique [0002] At present, the biological agents used for antibacterial and anti-inflammatory include vaccines, antibiotics, anti-inflammatory enzymes and egg yolk immunoglobulin (IgY), etc. The development and application of vaccines, antibiotics, and anti-inflammatory enzyme biological agents has a history of nearly a hundred years. The research on the development and application of yolk immunoglobulin (IgY) is a hot topic emerging in recent years. [0003] The current global prevention and treatment of respiratory infections, pharyngitis and tonsillitis caused by bacteria generally adopt the following methods: [0004] (1) Usi...

Claims

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Application Information

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IPC IPC(8): A61K39/395A61K9/12A61K47/42A61P11/04A61P11/00A61P31/04
Inventor 罗鑫龙李同森高利峰陈健芬
Owner 浙报数字文化集团股份有限公司
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