Composition for improving intestinal microflora
A technology of intestinal microorganisms and compositions, applied in the directions of drug combination, bacteria used in food preparation, application, etc., can solve the unsatisfactory intake of bifidobacteria proliferation factors, enhance the osmotic pressure of intestinal contents, and production methods complexity, etc.
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Embodiment approach 1
[0056] (experimental design)
[0057] The following human experiments were performed with informed consent according to the Helsinki declaration. The test subjects were 9 healthy Japanese men and women who had regular defecation and usually defecated every day. The male to female ratio of the experimental subjects was 2 males and 7 females. The background of the experimental subjects was as follows: age 27.1±6.8 (mean±standard deviation), BMI 21.6±1.9 (mean±standard deviation). Experimental subjects met with doctors at the beginning and end of the experiment. The progress of this experiment is shown in figure 1 middle.
[0058] The experimental period was 28 days, and the -7th day to the -1st day were set as the "pre-intake stage". During this stage, no ingestion containing 4×10 8 cfu / g or more of Lactobacillus paracasei KW3110 yoghurt (hereinafter referred to as KW yoghurt) as live cells; day 0 to day 6 is set as "100g-intake phase" and ingested every day during this pha...
Embodiment approach 2
[0096] (experimental design)
[0097] The subjects of the experiment were 10 healthy Japanese adult women who had a tendency to be constipated. The background of the experimental subjects was as follows: age 22.90±3.57 (mean±standard deviation), BMI 20.55±2.75 (mean±standard deviation). Experimental subjects met with doctors at the beginning and end of the experiment. The progress of this experiment is shown in image 3 middle. The experimental period is 21 days, and the -7th day to the -1st day are set as the "pre-intake phase", during this period, KW yoghurt is not ingested; the 0th day to the 13th day is set as the "intake phase" , the daily intake of KW yoghurt during this phase is 100g. In this stage, the 0th day to the 6th day are set as the "first week", and the 7th day to the 13th day are set as the "second week". In the experimental stage, the intake of foods that affect the intestinal microbial flora, including yoghurt other than KW yoghurt, lactic acid bacteria...
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