Chewing soft capsule shell, chewing soft capsule drug and prepration method thereof

Abstract

The invention relates to a chewing soft capsule shell, a chewing soft capsule drug and a prepration method thereof. The soft capsule shell consists of the following raw materials: 25-35 wt% of gelatin, 15-25 wt% of glycerol, 35-50 wt% of purified water, 0.1-1 wt% of sodium alginate, 0.1-1 wt% of carrageenan, 0.1-1 wt% of pectin, 1.5-2.5 wt% of sorbitol and 2-5 wt% of polyvinyl alcohol 400. The chewing soft capsule shell further comprises the following components: 0.1-0.3 wt% of sweetener, 0.2-0.4 wt% of acidifier, 0.001-0.01 wt% of spice, 0.001-0.01 wt% of preservative and 0.001-0.01 wt% of pigment. The soft capsule shell prepared by the raw materials has the advantages of small mechanical strength and toughness, and the invention further provides the method for preparing the chewing softcapsule drug.

Description

Technical field

[0001] The invention relates to a soft capsule, specifically a chewable soft capsule skin and capsule medicine thereof, and belongs to the technical field of medicine. Background technique

[0002] As an emerging drug delivery system, soft capsules can effectively ensure good efficacy and stability of the contents due to their unique characteristics of closed soft packaging, and are widely used due to their inherent dose controllability and portability. In recent years, with the aim of improving the ease of taking pharmaceutical preparations, there has been an increasing demand for chewable soft capsules that are easy to take even without water. Therefore, the chewable soft capsule skin was prepared by adding an appropriate amount of glycerol and sorbitol to the raw materials of the soft capsule skin. However, just improving the chewability of chewable soft capsule skins is far from meeting the requirements of users. Therefore, chewable soft capsule products...