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Development of novel indoor acaricide

An acaricide and a new type of technology are applied in the research and development of new indoor acaricides and their preparation fields, which can solve the problems of serious environmental pollution, long-term use, and large toxic and side effects of chemically synthesized acaricides, so as to reduce pollution and use The effect of convenience, reduced cost and difficulty of production

Inactive Publication Date: 2010-01-27
刘志刚
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The present invention aims to overcome the disadvantages of chemically synthesized acaricides, such as large toxic and side effects, long-term use, and serious environmental pollution, and to develop a new type of acaricide that can effectively disinfect house dust mites, dust mites and other dust mites. The acaricide has the characteristics of convenience, speed, high efficiency, low toxicity, and no pollution to the environment. It is refined from traditional Chinese herbal medicines combined with modern extraction and preparation processes.

Method used

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  • Development of novel indoor acaricide
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Examples

Experimental program
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Effect test

Embodiment 1

[0020] The preparation of embodiment 1 clove oil

[0021] Clove, a traditional Chinese medicinal material, was dried at 45°C, crushed, installed with a Soxhlet extractor, heated in a water bath, and petroleum ether (II) was used as a solvent to extract the effective components of clove. The extract was vacuum filtered to remove impurities, adding anhydrous Na 2 SO 4 Dry and remove the solvent with a rotary evaporator to obtain the extract. Embodiment 2 direct contact method test clove oil acaricidal activity

Embodiment 2

[0022] Set a certain highest concentration of clove oil, double-dilution to 8 concentrations in turn, absorb 300μl respectively and evenly absorb on filter paper with a diameter of 5.6cm. Put the culture dish of adult mites into a constant temperature incubator, and observe the killing of mites after 24 hours. Count the number of dead mites (under the dissecting microscope, lightly poke the mite body with a needle 3 times, and the mites do not move their limbs, it can be judged that the mites are dead), calculate the mortality rate, repeat 3 times, and calculate LD 50 .

Embodiment 3

[0023] Embodiment 3 fumigation method tests the acaricidal activity of clove oil

[0024] Put the filter paper with a diameter of 7 cm into the lid of a petri dish with a diameter of 6 cm, absorb 300 μl of extracts of different concentrations and evenly absorb on the filter paper, after the solvent is completely evaporated, place the filter paper in a place where a certain number (60±10) of adult mites on the petri dish and placed in a constant temperature incubator. After 24 hours, observe the killing of mites and calculate LD 50 .

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Abstract

The invention discloses a method for developing a novel indoor acaricide. The novel acaricide uses clove and other Chinese medicinal materials as raw materials, the main active component thereof is eugenic acid, and the novel acaricide is a pure natural chemical substance, has no notable harms to human bodies and other organic bodies, has no potential hazards to the environment too, and can be widely applied to killing, preventing and controlling various dust mites of dermatophagoides pteronyssinus, dermatophagoides farinae and the like in various regions and various indoor environments. The novel acaricide can effectively control the number of the dust mites in the living environments of people, greatly reduce the density of dust mite allergens in the indoor environments, and significantly reduce the disease incidence of dust mite anaphylactic diseases. Besides, the novel acaricide has outstanding effects of preventing and performing adjuvant therapy on various anaphylactic diseases taking the dust mites as the allergens, such as allelgic asthma, rhinitis and the like.

Description

technical field [0001] The invention belongs to the technical field of hygienic insecticides, and in particular relates to the research and development of a novel indoor acaricide and its preparation technology. Background technique [0002] With the continuous improvement of the degree of industrialization worldwide, the incidence of allergic diseases is increasing year by year worldwide. In August 2005, the World Allergy Organization (WAO) announced the results of an epidemiological investigation of allergic diseases in 30 countries on the first World Allergic Disease Day: Among the 1.2 billion total population in these countries, 22% (250 million people) Humans) suffer from immunoglobulin E (IgE)-mediated allergic diseases, such as allergic rhinitis, asthma, conjunctivitis, eczema, food allergy, drug allergy and severe allergic reaction, etc. More than 50 million people in the United States suffer from allergic diseases, 10%-30% of adults and 40% of children suffer from ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N65/00A01N31/08A01P7/02
Inventor 刘志刚吴海强李静
Owner 刘志刚
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