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Application of methylene blue used as cancer-philic targeting substance and nano medicine containing methylene blue

A nano-drug, methylene blue technology, applied in the direction of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of lack of specificity, normal body damage, tumor killing effect, etc.

Inactive Publication Date: 2010-02-17
王永清
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, anti-cancer drugs are still lack of specificity, they have a killing effect on tumors, but also damage the normal body. The research on anti-cancer targeted drugs is imminent, which is the desire of scientists.

Method used

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  • Application of methylene blue used as cancer-philic targeting substance and nano medicine containing methylene blue
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  • Application of methylene blue used as cancer-philic targeting substance and nano medicine containing methylene blue

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Embodiment Construction

[0013] The invention provides an application of methylene blue as an anti-cancer targeting substance,

[0014] The present invention also provides a nano drug containing methylene blue

[0015] The nano medicine of methylene blue is prepared by including methylene blue.

[0016] When the nano-medicine containing methylene blue is an oral liquid, the content of methylene blue is 0.5-1.2%, 2-10mL / bottle; when the nano-medicine containing methylene blue is an injection, the content of methylene blue is 0.02%-1%. , 200mL / bottle; when the nanomedicine containing methylene blue is a tablet, the methylene blue content is 8-12%, 0.3g / tablet.

[0017] The present invention also provides a method for preparing the above-mentioned nanomedicine containing methylene blue, which is special in that: the method comprises the following steps:

[0018] 1) Feeding: feeding according to the content, concentration and dosage of methylene blue;

[0019] 2) Preparation: prepared under 100-grade p...

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Abstract

The invention relates to an application of methylene blue used as a cancer-philic targeting substance and a nano medicine containing the methylene blue. According to the characteristics of the methylene blue, an anticancer targeting medicine which not only has obvious anticancer targeting property but also has favorable anticancer effect is prepared. Simultaneously, the invention also searches outa special technological method for producing the anticancer targeting medicine according to the characteristics of the anticancer targeting medicine, and the method does not need to be added with aninitiator, can initiate the mutual polymerization of each component by generated shock waves and micro jets and can obtain a product with high purity.

Description

technical field [0001] The invention belongs to the technical field of anti-cancer targeting drug research, specifically, the invention relates to the application of methylene blue as a carcinogenic targeting substance, and the methylene blue anti-cancer targeting nano-medicine, its application and its preparation method. Background technique [0002] "China Cancer Prevention and Control Planning Outline (2004-2010)" clearly pointed out that "Since the 1970s, the incidence and mortality of cancer in my country have been on the rise. Among urban residents, cancer has accounted for the first place in the cause of death, and more than 80% of cancers have reached an advanced stage when they are diagnosed clinically, losing the chance of surgical treatment. Systemic chemotherapy is one of the important means for treating tumors. At present, anticancer drugs still lack specificity. It has a killing effect on tumors, but also damages the normal body. The research on anti-cancer targe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/22A61K45/00A61K31/5415A61P35/00
Inventor 王永清
Owner 王永清
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