Pharmaceutical composition for treating hepatitis B and preparation method thereof

A technology of hepatitis B and composition, which is applied in the field of pharmaceutical composition for treating hepatitis B and its preparation, which can solve the problems of difficult treatment of chronic hepatitis B and unsatisfactory effect of hepatitis B, and achieve protection of liver cells and removal of tiny Effect of thrombus and accelerated excretion

Inactive Publication Date: 2010-05-05
ZHEJIANG PHARMA COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

New drugs such as Yiganning Granules, Yigan Jieqiao Capsules, Jigucao Pills, and Yigan Powder, which are currently in clinical use, have unsatisfactory effects in treating hepatitis B, and their exact curative effects still need further research and verification.
Especially the treatment of chronic hepatitis B is very difficult, the key is to completely suppress and remove hepatitis B virus; adjust the body's immunity, protect liver cells, block chronicity (hepatic fibrosis), there is no ideal drug so far

Method used

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  • Pharmaceutical composition for treating hepatitis B and preparation method thereof

Examples

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Embodiment 1

[0018] The various methods of making granules of the present invention:

[0019] Weigh each raw material; Ganoderma lucidum polysaccharide 450 grams, Clover 400 grams, Bamboo root seven 400 grams, Bupleurum 150 grams.

[0020] Except Ganoderma lucidum polysaccharide, grind the above drugs into coarse powder, decoct twice in water, the first time for 3 hours, the second time for 2 hours, filter, the filtrate is concentrated into a thick paste, dried, crushed through a 100-mesh sieve, add Ganoderma lucidum polysaccharide, Take out when mixing, moistening, softening, and agglomeration, and make granular granules.

[0021] Similarly, according to the method of Example 1, it can be made into tablets or capsules by adding suitable additives.

[0022] The preparation of the present invention is brownish-yellow granules or gray-black tablets or capsules, with aromatic odor, slightly bitter taste, non-toxic, and is pure Chinese medicine compound granules or tablets or capsules.

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Abstract

The invention discloses a pharmaceutical composition for treating hepatitis B and a preparation method thereof. The pharmaceutical composition is prepared by the following components: ganoderma lucidum polysaccharide, radix tetrastigme, disporopsis fuscopicta, radix bupleuri and the like. The preparation method comprises the following steps: weighing the raw materials according to the formula ratio; grinding the above raw materials into coarse powder except for ganoderma lucidum polysaccharide; decocting with water twice, wherein, the first decocting lasts 3h, and the second decocting lasts 2h, filtering, concentrating the filtrate into thick paste; drying, pulverizing; sieving with a 100 meshes sieve; adding ganoderma lucidum polysaccharide; evenly mixing, moistening, softening, and taking out agglomerated product to obtain medicinal granules. The compound preparation prepared by the method of the invention adopts oral dosage form, has convenient use and good mouth feel, is easy to accept by the patients, and has strong function of inhibiting and removing hepatitis B virus, and the negative conversion ratio of HBsAg can reach over 58% after the patient takes the pharmaceutical composition for 6 months; the compound preparation has low treatment cost and can save over 68% of cost compared with the conventional treatment.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a medicine composition for treating hepatitis B with traditional Chinese medicine as the main component and a preparation method thereof. Background technique [0002] Hepatitis B is a disease with global distribution and great social harm. According to an incomplete survey by the World Health Organization, more than 1 million people die of hepatitis every year in the world. my country is now a high-incidence area of ​​hepatitis, and the infection rate of hepatitis B virus in the national population is 42%-80%, and about 1 / 4 of the carriers of hepatitis B virus eventually develop into liver cirrhosis and primary liver cancer, accounting for about 50% of the world's hepatitis B virus. more than half of the patients. Hepatitis B is a multi-organ involvement, low function performance, complex pathogenesis, long course, easy to relapse, difficult to cure disease. Modern medicine still has ...

Claims

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Application Information

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Patent Type & AuthorityApplications(China)
IPC IPC(8): A61K36/896A61P1/16A61P31/20A61K31/715
Inventor杨雄志喻楚荣
OwnerZHEJIANG PHARMA COLLEGE